Professional Documents
Culture Documents
Guillainbarresyndrome 200729103710
Guillainbarresyndrome 200729103710
SYNDROME
DEFINITION
• Guillain Barre syndrome is a rare disorder in
which body's immune system attacks nerves and
causes damage to the peripheral nerves.
• The nerve injury often causes muscle weakness,
cause paralysis and sensitivity problems, including
pain, tingling or numbness.
The demyelinating
form
of Guillain-Barre
syndrome destroys the
covering
protectiv
the peripheral
of nerves
e(myelin sheath),
preventing nerves
the transmitting signals
from
to the brain.
Types
Once thought to be a single disorder, Guillain-Barre
syndrome is now known to occur in several forms. The
main types are:
– Acute Inflammatory Demyelinating
Polyradiculoneuropathy (AIDP) The most common sign
of AIDP is muscle weakness that starts in the lower part of
your body and spreads upward.
– Miller Fisher Syndrome (MFS), in which paralysis starts in
the eyes. MFS is also associated with unsteady gait.
– Acute Motor Axonal Neuropathy (AMAN) and Acute
Motor-sensory Axonal Neuropathy (AMSAN)
ETIOLOG
• Y
Bacterial infection
• Viral infection
• Protozoan infection
• Surgeries
• Blood Transfusion
• Transplantation
• Anesthesia
• Preceding heat stroke
• Preceding vaccination – Swine flu
PATHOPHYSIOLOGY
Infection with organism contain amino acid that mimic peripheral
nerve myelin