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GEN BIO1 Q1 Week3
GEN BIO1 Q1 Week3
• Stem cells
• Fat cells (adipocytes)
• Skin cells (epithelial cells)
• Endothelial cells responsible for
angiogenesis
• Cancer cells
Guide Questions:
• G1:What is the role of
chromosomes in cell division?
• Chromosomes make it possible
to separate DNA precisely
during cell division.
• G2: What are some of the
difficulties a cell faces as it
increases in size?
• the larger a cell becomes, the
more demands the cell places
on its DNA
• larger cell is less efficient in
moving nutrients and waste
materials across the cell
membrane
• G3: How do cells undergo
growth and repair? Give an
example of a scenario
• G4: Describe what happens
during checkpoints
• Cell go through a series of
events known as cell cycle as
they grow and divide
• During cell cycle, a cell
grows, prepares for division,
and divides to form two
daughter cells
EVALUATION
(1/8 sheet)
Mitosis
Trait Survey
Organism Haploid Diploid
Amoeba N=25
Chimpanzee N=24
Earthworm N=18
Fern 2N=1010
Hamster N=22
Human 2N=46
Onion 2N=16
Guide Questions:
• 1. Calculate: What are the
haploid numbers for fern and
onion plants?
• 2. In the table, which
organisms’ diploid numbers
are closest to that of a
human?
• 3. Why is diploid number
always even?
• 4. Which organism’s haploid
and diploid numbers do you
find the most surprising?
Why?
Meiosis
Guide Questions
• How many sets of genes are
found in most adult
organisms?
• Diploid (2N=6)
• Haploid (N=3)
• What events occur during
each phases of meiosis?
Meiosis I Meiosis II
• Prophase I • Prophase II
• Metaphase I • Metaphase II
• Anaphase I • Anaphase II
• Telophase I • Telophase II
– Cytokinesis I – Cytokinesis II
Meiosis I
Prophase I
• Each replicated chromosomes
pairs with corresponding
homologous chromosomes
• This pairing forms a structure
called tetrad
• create tetrads (XX) by pairing
homologous chromosomes
(crossing over)
Metaphase I
• Paired homologous
chromosomes (tetrads ) line up
along the metaphase plate
• It is when independent
assortment takes place
Anaphase I
• Homologous chromosomes
move to opposite ends of the
cell
• Spindle fibers pull each
homologous chromosome pair
toward opposite ends of the
cell
Telophase I
• Equal number of chromosomes
is observed in each of the
nuclei
• Nuclear membrane forms
around each cluster of
chromosomes
Cytokinesis I
• Divide the cell membrane so
that its result will be two
daughter cells
• These daughter cells are now
haploid (n), wherein the
number of chromosomes has
been halved
Meiosis II
Prophase II
• Each of the two cells should
contain the chromosomes made
up of sister chromatids
• Chromosomes must consists
of two chromatids
Metaphase II
• Align the chromosomes along
the middle of each cells
Anaphase II
• Separation of the sister
chromatids
• Movement of one sister
chromatid from each
chromosome to opposite sides
of the cell
Telophase II
• At this stage, there will be four
nuclei , with two single
chromatids in each of the cells
Cytokinesis II
• Division of the cell membrane
so that it will produce four
daughter cells
Mitosis vs Meiosis
Comparing Mitosis and Meiosis
Meiosis
Process DNA Synapsis Cross Homolo- Sister Number
Synthesis of over gous chroma- and
homolog chromo- tids line genetic
ous
somes up at composi
chromo-
somes
line up the -tion of
at the meta- daughter
meta- phase cells
phase plate
plate
Mitosis S phase Does not Does not Does not Metaphase Two
of occur in occur in occur in diploid
interphase mitosis Mitosis mitosis cells at
the end
of
mitosis