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  • Amino Acids

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    Amino acids are organic compounds that have a central carbon atom bonded to an amino group, a carboxyl group, a hydrogen atom, and a variable side chain. They are the building blocks of proteins. Some key properties include that they can be grouped based on their start letters or abundance in proteins. Their isoelectric point is determined by taking the average pH between their zwitterionic and deionized forms. Some amino acids have permanent modifications found in specific proteins, while others have reversible modifications. Cysteine can form disulfide bonds between two cysteine residues.

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    Amino acids are organic compounds that have a central carbon atom bonded to an amino group, a carboxyl group, a hydrogen atom, and a variable side chain. They are the building blocks of proteins. Some key properties include that they can be grouped based on their start letters or abundance in proteins. Their isoelectric point is determined by taking the average pH between their zwitterionic and deionized forms. Some amino acids have permanent modifications found in specific proteins, while others have reversible modifications. Cysteine can form disulfide bonds between two cysteine residues.

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    6 views11 pages

    Amino Acids

    Uploaded by

    ayeshasaleem107112
    Amino acids are organic compounds that have a central carbon atom bonded to an amino group, a carboxyl group, a hydrogen atom, and a variable side chain. They are the building blocks of proteins. Some key properties include that they can be grouped based on their start letters or abundance in proteins. Their isoelectric point is determined by taking the average pH between their zwitterionic and deionized forms. Some amino acids have permanent modifications found in specific proteins, while others have reversible modifications. Cysteine can form disulfide bonds between two cysteine residues.

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    of 11

    Amino Acids

    COOH
    COO-
    Core Structure
    NH23+ C H

    • A central carbon (The α Carbon)


    • Amino group (-NH2) R
    At Physiological pH
    • Carboxyl group (-COOH)
    • A Hydrogen (-H)
    • A variable group (-R)
    Amino Acids- Groups
    Amino Acids- Groups
    Amino Acids- Groups
    Some Useful Properties

    CHIMSV- Amino Acids with unique start letters


    AGLPT- Amino Acids most abundantly found in proteins
    RFYW- Amino Acids given symbols on the basis of phonetics
    DNEQ – Assigned letters found within or suggested by their names
    K- given to lysine because this is closest to L in alphabets
    Amino Acid- Titration

    pI = Taking average between pH at Zwitterionic form


    pI = And
    pI = pH at completely deionized form
    Amino Acid- Titration
    Unconventional Amino Acids
    Permanent Modifications
    1

    2 3

    4 5

    6 1- Found in all plant cell wall proteins


    1 & 2- Found in collagen
    3- Found in prothrombin
    4- Found in myosin
    5- Found in antioxidant proteins
    6- Found in elastin protein
    Unconventional Amino Acids
    Reversible Modifications
    Special Case of Cysteine

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