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DRUGS
DRUGS
2
A drug is any substance (with the
exception of food and water) which, when
taken into the body, alters the body's
function either physically and/or
psychologically.
Drugs may be legal (e.g. alcohol, caffeine
and tobacco) or illegal (e.g. cannabis,
ecstasy, cocaine and heroin).
Substances used as a medicine or in making
medicines, which affects the body and mind
and have potential for abuse.
It can be harmful.
It can be either NATURAL and
SYTHETIC/ARTIFICIAL.
Natural Drugs
- include natural plant leaves, flowering
tops, resin, hashish, opium and
marijuana.
Synthetic/Artificial Drugs
- are drugs produced by clandestine
laboratories that are controlled by law
because they are used in medical practice.
World Health Organization
1. Book of Judges
Analgesics
are drugs that relieve pain.
There are two main types:
non-narcotic analgesics for mild pain, and
Narcotic analgesics for severe pain.
Antacids
Drugs that relieve indigestion and
heartburn by neutralizing stomach acid.
Antihistamines – those that
control or combat allergic reactions.
Contraceptives – drugs that
prevent the meeting of the egg cell
and sperm cell or prevent the ovary
from releasing egg cells.
Decongestants –those that relieve
congestion of the nasal passages.
Expectorants – those that can ease
the expulsion of mucus and phlegm
from the lungs and the throat.
Laxatives – those that stimulate
defecation and encourage bowel
movement.
Sedatives and Tranquilizer – are those that can
calm and quiet the nerves and relieve anxiety
without causing depression and clouding of the
mind.
DOSE
A dose of drug refers to the amount taken by the
patient at one time. The dose taken becomes
extremely important part of developing drug abuse.
There are many factors taken into consideration
when deciding a dose of drug - including age of the
patient, weight, sex, ethnicity, liver and kidney
function and whether the patient smokes or drinks
alcohol. Other medicines may also affect the drug
dose.
Classification of Drug Dosage
1. Minimal dose
The amount needed to treat or heal that is, the
smallest amount of a drug that will produce a
therapeutic effect.
ORAL
Thisis the safest and most convenient and
economical route whenever possible. There
are however, drugs which cannot be
administered this way because the
digestive juices readily destroy them or
because they irritate the mucous lining of
the gastro –intestinal tract and induce
vomiting.
PARENTAL
parenteral medications are introduced by
injection. All drugs used by this route must
be pure, sterile, pyrogen-free, and in a liquid
state. There are several methods of
parenteral administration, including
subcutaneous, intradermal, intramuscular,
intravenous, and intra thecal or intra spinal.
SUBCUTANEOUS— the drug is
injected just below the skin’s
cutaneous layers. Example: Insulin.
INTRATHECAL OR
INTRASPINAL— The drug is
introduced into the subarachnoid
space of the spinal
column. Example: Procaine
hydrochloride.
INHALATION—Inhalation is a
means of introducing medications
through the respiratory system in the
form of a gas, vapor, or powder.
Inhalation is divided into three major
types: vaporization, gas inhalation, and
nebulization
TOPICAL—Topical drugs are applied to a surface area
of the body. Topically applied drugs serve two
purposes: Local effect: The drug is intended to
relieve itching, burning, or other skin conditions
without being absorbed into the bloodstream.
Systemic effect: The drug is absorbed through the
skin into the bloodstream. Examples of topical
preparations are ointments, creams, lotions, and
shampoos.
Allergy – some drugs cause the release of histamine giving rise to allergic
symptoms such as dermatitis, swelling, fall in blood pressure, suffocation
and death.
Poisonous Property – drugs are chemicals and some of them have the
property of being general protoplasmic poisons.
Side Effects – some drugs are not receptors for one organ but receptors
of other organs as well. The effect in the other organs may constitute a side
effect, which are most of the time is unwanted.
STIMULANTS INDUCE
ALLERTNESS, WAKEFULNESS,
ELEVATED MOOD, INCREASE
SPEECH, MENTAL AND MOTOR
ACTIVITY, RELIEVE FATIGUE OR
BOREDOM AND DECREASE
APPETITE.
IMMEDIATE EFFECTS OF STIMULANTS
Dilated pupil
Increase in blood pressure/heart
rate/breathing rate/body
temperature
Involuntary muscle twitching
Less hunger
Slurred speech
Depressant – These are drug that has the
effect of depressing the central nervous system
causing initial relaxation leading to
drowsiness and sleep.
Used of drowsiness results to impairment of
judgment, hearing, speech and muscle
coordination. The dull the minds, slow
down the body reaction to such extends
those accidental death and suicidal
usually happen.
Hallucinogens are drugs that produce reactions such as
perceptual alterations and changes in the
state of consciousness.
They consist of variety altering drugs, which
distort reality, thinking and perception of
time, sound, space and sensation.
Immediate effects:
Hallucinations/illusions
Faster heartbeat and pulse rate
Bloodshot eye/blurred vision/rem
Forgetfulness/ inability to think
Altered sense of time
Impaired reflexes, coordination and concentration
Food trip and sleepiness(mj)
4.Inhalants –
Although not a drug but these are
household and industrial chemicals whose
volatile vapors or pressurized gases are
concentrated and breathed in via the nose
or mouth and produces intoxication, in a
manner not intended by the manufacturer.
These substances include the following :
LEGAL DEPRESSANTS
Alcohol
The king of all drugs with potential for
abuse.
Alcohol is the most general legal
depressant. There are different types
of alcohol such as beer, wine and
liquor.
BARBITURATES
are drugs used for inducing
sleep in persons plagued
with anxiety, mental stress
and insomnia.
They are also of value in the
treatment of epilepsy and
hypertension.
They are available in
capsules, pills or tablets
and taken orally or injected.
This group of drugs is also known as sedative-
hypnotics. They help in sleep disorders and
reduce anxiety. Barbiturates generate impacts ranging
mild sedation to entire anesthesia. They can be injected
directly into veins and muscles but regularly taken in pill
form. Signs of intoxication comprise respiratory
depression, low blood pressure, exhaustion, fever,
strange excitement, irritability and seizures. The
major risk of intoxication is respiratory depression.
Other impacts of barbiturate overdoes include
drowsiness, slurred speech and loss of inhibitions.
Barbiturates are classified as:
A. Pentobarbital – Yellow
jackets
C. Amobarbital – blue
devils/blue birds
D. Amosbarbital –
rainbow/double trouble
Street name: LILY,
BALA, DOWNERS,
YELLOW JACKETS,
BLUE HEAVENS
TRANQUILIZERS
are dugs that calm and
relax and diminish
anxiety.
They are used in the
treatment of nervous
states in some mental
disorders without
producing sleep.
Household Sprays
Gamma-Hydroxybutyric Acid (Rohypnol)
A tincture of opium in
combination with camphor.
Commonly used as a household
remedy for diarrhea and abdominal
pain.
Paregoric – the name paregoric means “soothing
preparation”
Seconal
A drug commonly used by hospitality
girls. Sudden withdrawal from this drug
is even more dangerous than opiate
withdrawal.
The dependent develops generalized
convulsions and delirium, which are
frequently associated with heart and
respiratory failure
Depressants
Methaqualone
Is a synthetic sedative which has
been widely abused and often
caused serious poisoning. It is a
sedative drug in a smaller dose and a
hypnotic in a bigger dose.
The effect is similar to barbiturates
and action is within 30 minutes after
administration; the effect is for 6 –
10 hours.
Narcotics – it is derived from the Greek work
“narkoticos” meaning sleep.
- term originally applied to all compounds that
produce insensibility to external stimuli through
depression of the central nervous system.
these are generally use as pain killing drugs, it relieves
pain and produce profound sleep or stupor.
Stimulants
Stimulants (uppers)
These are drugs that produce
excitation, alertness and wakefulness,
intense feeling of “highness” and in
some cases, a temporary rise in blood
pressure and respiration.
Stimulants
Amphetamines
A group of synthetic drugs, increasing the
heart rate and raising blood pressure.
Used medically for weight reducing in obesity,
relief or mild depression and treatment of
narcolepsy.
Macaulay Culkin
– Actor –Home Alone
Defect cause by smoking Marijuana
Two Varieties of the Cannabis
Plant
Resin – Producing – (female mj) –
THC is found most abundantly in the
upper leaves, barks and flowers of the
resin – producing plant.