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Marisa Yoder MSN, RN
Sepsis Champion
St. Lukes Meridian ICU
Surviving Sepsis Guidelines Updates
2021
“For adults with septic shock, we suggest using capillary refill time to guide resuscitation
as an adjunct to other measures of perfusion”.
“For adults with septic shock on norepinephrine with inadequate mean arterial pressure
levels, we suggest adding vasopressin instead of escalating the dose of norepinephrine”.
”For adults with septic shock, we suggest invasive monitoring of arterial blood pressure
over noninvasive monitoring, as soon as practical and if resources are available”.
”For adults with septic shock, we suggest starting vasopressors peripherally to restore
mean arterial pressure rather than delaying initiation until central venous access is
secured”.
“For adults with sepsis-induced hypoxemic respiratory failure, we suggest the use of
high-flow nasal oxygen over noninvasive ventilation”.
“For adults with sepsis or septic shock, we suggest against using IV vitamin C”.
“For adults with sepsis or septic shock, we recommend that the principles of palliative
care (which may include palliative care consultation based on clinician judgement) be
integrated into the treatment plan, when appropriate, to address patient and family
symptoms and suffering”.
Skin mottling is defined as a patchy
skin discoloration.
Mottling reflects a reduction in skin
blood flow.
It is a sign of cutaneous hypoperfusion
What Causes that typically manifests around the
knees.
Mottling in Recent studies revealed a significant
relationship between mottling
Sepsis? extension and visceral organ vascular
tone.
Therefore, mottling may reflect
intestinal organ perfusion. (Storz &
Seidlitz, 2020).
Knee Mottling Score