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Exercise physiology in internal diseases:

diabetes

Prof. dr. Dominique Hansen


dr. Charly Keytsman
Prof. dr. Chris Burtin
Many T2DM patients are obese
 Be aware of disurbances related to obesity
Changes in glucose and insulin
unit

Glucose
healthy

Insulin
healthy

Exercise time
Changes in glucose and insulin

Glucose
T2DM
unit

Insulin
T2DM

Treated with metformin

Exercise time
Changes in glucose and insulin

Insulin
T2DM
unit

Treated with sulfonylurea Hypoglycemia


Glucose
T2DM

Exercise time
Changes in glucose and insulin

Insulin
T2DM and T1DM
unit

Treated with insulin Hypoglycemia


Glucose
T2DM

Exercise time
Autonomic neuropathy

 Slowed heart rate recovery


 Predicts poor prognosis

 Disturbed blood pressure responses


 Be aware for exercise hypo/hypertension
Autonomic neuropathy
 Silent myocardial ischemia
 No angina pectoris does not exclude coronary artery
disease, especially in diabetes patients
Diabetic cardiomyopathy

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