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Diabetes Final
Diabetes Final
● During the procedure, the deceased person's body is opened and the organs are
removed for the examination. When the post mortem is done, the organs are
returned and the body is stiched.
● The aim of post mortem is to determine the cause of death. Post mortem provides
various information about when, how and why someone died.
Types of post mortem
● 1. Coroner's post mortem examination:
● A coroner is a judicial officer responsible for the investigation of death in certain
death. They are usually lawyers or doctors with the experience of minimum 5 years.
A death will be referred to the coroner if:
● It is unexpected, such a sudden death
● # It's violent, unnatural or suspicious, such as suicide
● # The result of accident or injury
● # It occurred during or after the hospital procedure
● The main aim of post mortem requested by the coroner is to find out how someone
died and decided whether an inquest is needed. A coroner may decide to hold an
inquest after a post mortem has been completed. Sample of organs may need to be
2. Hospital post mortem examination:
Post mortems are sometime requested by hospital doctors to provide more information
about illness or the cause of death. Sometimes the relative of the deceased request the
hospital for post mortem to find more details about the death.
● Factors affecting post mortem changes
Intrinsic factors
- involving the subject that affect postmortem changes primary include a body mass and
the surface area of the body.
Extrinsic factors
-that affect post mortem changes primary include the clothing and insulation, the
environment of the death scene and storage of body after death.
Classification of post mortem changes
Immediate post mortem changes
It is also known as rapid changes after death. It relate to the cessation of bodily functions
including the respiratory, circulatory and nervous system. The absence of cardiac and
respiratory sounds on auscultation over a period of 5 minutes indicates a sign of death.
Early post mortem changes
The changes in eye occur during the early post mortem period include corneal turbidity
and tache noire formation. The intraocular tension falls to nil in about 2 hours after
death.
Late post mortem changes
The changes that occur in this process are on a microscopic rather than a macroscopic
level. Autolytic changes are most prominent in the pancreas and other organ with high
Post mortem stages of death
Pallor mortis It is the first change that occur in a corpse, that is the paleness in the face
and other parts of the body. It is due to cessation of the capillary circulation. The first
sign is shown within 15 to 30 minutes of the death.
Algor mortis is the post mortem cooling of body temperature until
Livor mortis is also known as post mortem hypostasis or post mortem lividity. It is the
discoloration of the skin that varies from pink to dark purple. It begins to be apparent
about an hour after death.
Rigor mortis is the stiffening of the muscles of the body after death. Occurs 2-6 hours
after death. The rate at which rigor mortis passes off will be rapid in a hot environment
as the onset of the putrefaction is hastened in environment. Cold temperature lengthen
the duration of rigor.
Changes in skin at the time of post mortem
Livor mortis -It is the discoloration of skin
Vibices - These are the pale marks on a dead body that are caused by dermal pressure.
Like from the rope in case of hanging death.
Tardieu spots - These are the dark pinpoint spots on the dead body which are developed
in dependent areas. Like in the case of hanging death, the lags of the hanged person due
to increased gravitational pressure.
Venous pattering - These are the prominent purple discoloration of sub dermal vessels.
Degloving- They are the thermal exposure, immersions or advanced decomposition of
skin and tissues that result in degloving of skin. It is common in hands and feet of the
dead body.
Forensic significance
● Post mortem interval is the time between the death of a person and the time he is
found for post mortem. It is an essential tool in forensic investigation providing an
estimate time of death. It is pivotal in judicial cases and can even either incriminate
or acquit a suspect. Earlier a corpse is found, the more accurate the post mortem
interval estimation is to be.
Type 1 Diabetes Complications
● Age. 45 or older
● Family. A parent, sister, or
brother with diabetes
● Ethnicity. African American,
Alaska Native, Native American,
Asian American, Hispanic or
Latino, or Pacific Islander
American
Type 2 Diabetes Risk Factors
Risk factors related to your health and medical history include:
● Prediabetes
● Heart and blood vessel disease
● High blood pressure, even if it's treated and under control
● Low HDL ("good") cholesterol
Risk factors related to daily
● High triglycerides
habits and lifestyle:
● Being overweight or obese
● Getting little or no exercise
● Gestational diabetes while you were pregnant
● Smoking
● Polycystic ovary syndrome (PCOS)
● Stress
● Depression
● Sleeping too little or too much
Type 2 Diabetes Diagnosis and Tests
● A1c. This test measures average blood glucose levels for the
previous 2 or 3 months.
● Fasting plasma glucose. This test measures how much
glucose is in your plasma.
● Oral glucose tolerance test (OGTT). This checks your blood
glucose before and 2 hours after you drink something sweet to
see how your body handles the sugar.
Type 2 Diabetes Treatment
Managing type 2 diabetes includes a mix of lifestyle changes and medication.
Lifestyle Changes Medications
● Exercise ● Metformin (Fortamet, Glucophage,
● Watch your blood sugar levels. Glumetza, Riomet)
● Weight loss ● Sulfonylureas
● Healthy eating. There’s no specific diet ● Meglitinides
for type 2 diabetes. Focus on: ● Thiazolidinediones
○ Eating fewer calories ● DPP-4 inhibitors
○ Cutting back on refined carbs, ● GLP-1 receptor agonists
especially sweets ● SGLT2 inhibitors
○ Adding veggies and fruits to your ● GIP and GLP-1 receptor agonist
diet ● Insulin
○ Getting more fiber
Type 2 Diabetes Prevention
Adopting a healthy lifestyle can help you lower your risk of
diabetes.
● Lose weight
● Get active/Exercise
● Eat right
● Quit smoking
Type 2 Diabetes Complications
● Skin conditions
● Slow healing
● Hearing impairment
● Sleep apnea
● Dementia
● Heart and blood vessel disease
● Nerve damage (neuropathy) in limbs
● Other nerve damage
● Kidney disease
● Eye damage
Types and Classifications of Diabetes
● More thirst
● Peeing often
● Fatigue
● Blurry vision
Prediabetes Causes and Risk Factors
● Kidney disease
● Blindness
● High blood pressure
● Nerve problems (peripheral neuropathy)
● Loss of a limb (amputation)
Types and Classifications of Diabetes
Gestational Diabetes
This type develops in some women
during their pregnancy. Gestational
diabetes usually goes away after pregnancy.
However, if you have gestational diabetes
you're at higher risk of developing Type 2
diabetes later on in life.
There are two classes of gestational
diabetes. Women with class A1 can manage
it through diet and exercise. Those who
have class A2 need to take insulin or other
medications.
Symptoms of Gestational Diabetes
When you eat, your pancreas releases insulin, a hormone that helps
move a sugar called glucose from your blood to your cells, which use it
for energy.
You can lower your risk before you get pregnant by:
● Eating a healthy diet
● Staying active
● Losing extra weight
Gestational Diabetes Complications to the Baby
● https://www.webmd.com/diabetes/type-1-diabetes
● https://www.nhsinform.scot/illnesses-and-conditions/diabetes/type-1-diabetes#about-type-1-diabetes
● https://www.healthline.com/health/type-2-diabetes#diagnosis
● https://www.webmd.com/diabetes/what-is-prediabetes
● https://www.webmd.com/diabetes/gestational-diabetes
● https://www.mayoclinic.org/diseases-conditions/gestational-diabetes/symptoms-causes/syc-20355339
● https://www.cdc.gov/diabetes/basics/risk-factors.html
● https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/symptoms-causes/syc-20351193