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BIPOLAR DISORDER

CONTEXT
Signs/symptoms and time of onset: Cause: Bipolar I disorder:

Bipolar II disorder:

PHARMACEUTICALS

MOOD STABILIZERS MOOD STABILIZERS ANTIPSYCHOTICS ANTIDEPRESSANTS


Eg: Lithium Eg: Valproate - Second –generation antipsychotics used - Always administered with a mood stabilizer
Therapeutic use: Therapeutic use: - (see Schizophrenia Map) - Why?

Therapeutic use:

- See Depression Map

Mechanism of action: Mechanism of action:


- Not clear! - See lithium
- Acts directly on CNS Five SGAs used:

Pharmacokinetics: Adverse effects: Patient education in managing bipolar disorder:

Adverse effects:

Lithium vs valproate:
Why and when each is used…

Drug interactions:

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