Attacking the sources of aging, not just the

signs and symptoms.

WHAT S ageLOC?
SSTERS? OR MOTHER/DAUGHTER?
ageLOC HELPS EXPLAN.
Why Some People Look Years Younger
Than They Really Are.
EVOLUTON OF AGELOC:
HUMAN GENOME
Mapping of the human genome
2003 discovery after 20 years of research: 20,000 25,000 genes form
the human genome
Twenty Labs with hundreds of scientists (United States, the United
Kingdom, France, Germany, Japan and China)
$3 billion
WHAT DOES THS
TELL US ABOUT AGNG?
.......tgactgccaatttgccaataccaattattgggggaatatgcccaatatatgcccgag
accagtattatgactgccaatttgccaataccaattttggcgactggaatatgcccaatatatgcccgagacc
agtattatgactgccaatttgccaataccaattttggacgaatatgcccaatatatgcccgagaccagtattat
gactgccaatttgccaataccaattttgggtgaatatgcccaatatatgcccgagaccagtattatgactgcc
aatttgccaataccaattattgggggaatatgcccaatatatgcccgagaccagtattatgactgccaatttg
ccaataccaattttggcgactggaatatgcccaatatatgcccgagaccagtattatgactgccaatttgcca
ataccaattttggacgaattatatgcccgagaccagtattatgactgccaatttgccaataccaattttggacg
aatatgcccaatatatgcccgagaccagtattatgactgccaatttgccaataccaattttgggtgaatatgc
ccaatatatgcccgagaccagtattatgactgccaatttgccaataccaattattgggggaatatgcccaat
atatgcccgagaccagtattatgactgccaatttgccaataccaattttggcgactggaatatgcccaatata
tgcccgagaccagtattatgactgccaatttgccaataccaattttggacgaatatgcccaatatatgcccga
gaccagtattatgactgccaatttgccaataccaattttgggtgaatatgcccaatatatgcccgagaccagt
attatgactgccaatttgccaataccaattattgggggaatatgcccaatatatgcccgagaccagtattatg
actgccaatttgccaataccaattttggcgactggaatatgcccaatatatgcccgagaccagtattatgact
gccaatttgccaataccaattttggacgaatatgcccaatatatgcccgagaccagtattatgactgccaattt
gccaataccaattttgggtgaatatgcccaatatatgcccgagaccagtattatgactgccaatttgccaata
ccaattattgggggaatatgcccaatatatgcccgagaccagtattatgactgccaatttgccaataccaatt
ttggcgac........3 billion base pairs....
NU SKN'S AGNG EXPERTSE
LFEGEN PARTNERSHP
Dr. Richard Weindruch
Professor of Medicine
University of Wisconsin
Dr. Tom Prolla
Professor of Genetics
University of Wisconsin
STANFORD COLLABORATON
Stanford University
Two Dermatology Professors
Howard Chang, MD, PHD
Anne Chang, MD
Professor of Genetics
Stuart Kim, PhD
Published over 300
scientific papers, and
their insights have
changed the way aging
is viewed
Published over 300
scientific papers, and
their insights have
changed the way aging
is viewed
Anti-Aging experts
NU SKN SCENCE
1. Gene activity in skin
2. How did we discover YGCs?
3. How do YGCs influence skin?
4. 'Resetting' YGCs
OUR SPACE IN THE GENE WORLD:
DEFINING YOUTH GENE CLUSTERS
GENE ACTVTY N SKN
DNA Microarray Gene Map
Over 20000 Genes
DNA
Microarray
Heat Map
4 YGCS DENTFED
TMP1
COL7A1
AQP3
L1B
PPARG
TNFA
POMC
L1B
L6
SOD2
MT2A
TXNRD1
Pigment
20+
GENES
Cell
Turnover
35+
GENES
Hydration
20+
GENES
Skin
Structure
60+
GENES
Texture,
Smoothness
Radiance
Pore Size
Hydration
Discoloration
Skin Tone
Signs of Aging
Fine Lines &
Wrinkles
Youthful Skin
Structure
Youth Gene CIusters
Pigment
Hydration
Cellular
Turnover
ageLOC
Science
Skin
Structure
YGCs LNKED TO SGNS OF AGNG
ageLOC RESET
YGCs
DOWN
UP
T'S ABOUT BALANCE
Genes preserving youthfulness Genes accelerating aging
Down reguIation Up reguIation
GENE 1
GENE 2
GENE 3
GENE 4
GENE 5
GENE 6
GENE 1
GENE 2
GENE 3
GENE 4
GENE 5
GENE 6
REBALANCNG YGCs
Youth Gene
Cluster
Youth Gene
Cluster
FNDNGS PUBLSHED DEC 2009
DOWNLOAD SCENTFC POSTER
PUBLSHED DEC. 2009
FNDNGS PATENTED
The ageLOC science or the
ingredients in the ageLOC products
are protected by 14 patents that have
been approved or are in stages of the
review process with Patent and
Trademarks Offices in multiple
countries
ageLOC SCENCE
KEY MESSAGE PONTS
1. ageLOC science targets the ultimate sources
of aging
2. ageLOC science identifies Youth Gene
Clusters
3. ageLOC science resets Youth Gene Clusters
to more youthful patterns of activity
LOOKNG AHEAD
THE FUTURE: PHARMANEX AGELOC
Exclusive anti-aging research
and product innovation
coming Fall 2010!
Attack 84:7.08 of aging
internally
Extend ageLOC technology
to include nutrition
1. Attacks aging at its source genes
2. Youth gene cIusters identified in skin and linked to
clinical skin attributes
3. Resets YGCs restores skin
4. Findings published and protected by 14 patents and
patent applications around the world
5. Nu Skin's future products will address aging
incorporating key insights from experts
A TRULY TRANSFORMATONAL
EXPERENCE
Gentle Cleanse & Tone
Radiant Day
Transforming Night
Future Serum
ageLOC
GENTLE CLEANSE & TONE
Prepares the skin to
receive advanced
anti-aging ingredients
and ageLOC
Delivers the first
infusion of ageLOC
to the skin
Most advanced product in
Nu Skin history
Maximum concentration of
ageLOC
ageLOC & other Anti-
aging ingredients proven
to 2prove skn n 8
ways
ageLOC
FUTURE SERUM
ageLOC
RADANT DAY SPF 22
nfused with ageLOC and other
advanced anti-aging ingredients
proven to:
ncrease radiance, reduce
discoloration through
melanin inhibition
ncrease cell turnover by
85%
Reduce fine lines, wrinkles
& pores
Dramatically smooth and
soften skin
ageLOC
TRANSFORMNG NGHT
nfused with ageLOC and other advanced
anti-aging ingredients proven to:
Work with skin's natural nighttime repair
and renewal processes, strengthening
natural barriers
ncrease youthful cell turnover by 85%
Reduce look of fine lines, wrinkles &
pores
Dramatically smooth and soften skin
100%
BEST RESULTS
of the subjects started
showing improvements in
two or more signs of aging
in onIy 7 days based on
clinical assessments.
12-week clinical study
Consumer Perception
& Blinded Clinical
Graders
mprovement in 8
different signs of aging
The best results we've
ever seen at Nu Skin
Consumer Perception
THE PROOF
Consumer Perception
80%
THE PROOF
The Anti-Aging
Master
Simple Powerful!
GALVANC SPA

FACAL GELS
CONFRM: New genomic
research confirms that ageLOC
Facial Gels reset Youth Gene
Clusters in addition to slowing
arNOX enzyme.
PRE-TREAT GEL
Product Benefits
Pre-Treat Gel with the ageLOC
Face Conductor helps remove skin
impurities and let your pores
'breathe'.
Key Ingredients
Marigold extract, sea kelp and vanilla
extract soothe and condition the
skin.
Cocoyl Glutamatepurifies the skin.
TREATMENT GEL
Product Benefits
Treatment Gel with the ageLOC Edition
Galvanic Spa Face Conductor
revives and invigorates your skin.
Key Ingredients
ageLOCa patent-pending ingredient
technology that targets Youth Gene
Clusters, the ultimate sources of aging.
Argininean amino acid which helps
the skin to recover from stress
Magnesiuma necessary component
that promotes cellular energy
HOW DOES T WORK?
HOW DOES T WORK?
AGELOC EDTON GALVANC SPA
Delivers up to 5X's more
ageLOC ingredients to
the skin than the original
Galvanic Spa System .
Larger, brighter display
ntuitive usability
Enhanced ergonomics
Redesigned circuit board
provides optimized
current flow.
AGELOC EDTON GALVANC SPA
LASTNG BENEFTS
Nu Skin's patent pending
discovery, based on carefully
controlled research, reveals
that treatment with a galvanic
instrument may enhance the
delivery of key ingredients for
up to 24 hours. This includes
active ingredients contained in
subsequently applied
treatment products.
NEW ageLOC GALVANC SPA TOTE
GO MOBLE!