Nerve Lnd|ngs

Nerve Lnd|ngs
Notor Notor
nerve nerve endings endings
Effectors Effectors
e.g e.g motor motor end end
plate plate
Sensory Sensory
nerve nerve endings endings
Receptors Receptors
ClasslflcaLlon of recepLors ClasslflcaLlon of recepLors
@e source of te st|mu|us
a exteroceptors locaLed near Lhe body
surface
b |nteroceptors locaLed ln body vlscera and
blood vessels
c propr|oceptors locaLed ln [olnL capsule
Lendons and muscles
2- The type of the stimuIus:
a- mechanoreceptors: respond to
touch, stretch, vibration and
pressure.
b- thermoreceptors: respond to
temperature changes.
c- nociceptors: respond to pain.
d- receptors of speciaI sense: visual,
auditory, olfactory.
Accordlng Lo te|r structure recepLors can be classlfled
lnLo
!onencapsulated
free nerve
ending
pain
receptors
Thermo
receptors
Plexus of Bounet
Nerkel's disc
Encapsulated
9a|n keceptors ( 9a|n keceptors (noc|ceptors noc|ceptors) )
S|te
Wln Lhe skln Lhey reach up Lo
Lhe granular layer of Lhe
epldermls
WLhe corneal and buccal
mucosa
WLhe connecLlve Llssue of Lhe
Lympanlc membrane
WdenLal pulp
Structure
1hese are free nerve endlngs
LhaL peneLraLe Lhe basemenL
membrane and branch freely
lnbeLween Lhe eplLhellal cells
@ermoreceptors @ermoreceptors
W S|te Structure
1hese are free nerve
endlngs ramlfy aL
dermoepldermal
[uncLlon parallel Lo Lhe
skln surface
9|exus of 9|exus of 8ounet 8ounet
((per|tr|c|a| per|tr|c|a| INL) INL)
$ite & $tructure:
nerve endlngs LhaL
ramlfy around Lhe halr
folllcles
hat is the expected hat is the expected
function! function!
Merke/s Merke/s uisc uisc
erkeI's
ceII
TactiIe
disc
$ite & $tructure:
!resent in the deep
layer of epidermis of the
skin.
t is formed of 2
strucures:
1- tactile disc.
2- Merkel's cell.
unction:
mechanoreceptor
LncapsulaLed recepLors
W S|te
Sk|n |eve|
W S|ze
W Sape
Long|tud|na| ax|s
W Structure
Capsu|e
Core
Nerve
W S|te of entery of nerve
W Course of nerve
W @erm|nat|on of nerve
W Iunct|on
Meissner
!acinian Ruffini Krause
Melssner's Melssner's
corpuscle corpuscle
krause end bulb krause end bulb
eissner's
corpuscIe
Krause end
buIb
$ite
ingers & toes, Iip,
nippIe, eye Iid,
externaI genitaIia
$kin, conjunctiva,
Iip, tongue,
externaI genitaIia
$kin IeveI
ermal papillae ermal papillae
$ize
Moderate The smallest
$hape
Ovoid Spherical
LongitudinaI
axis
!erpendicular to skin
surface
CapsuIe
Well developed Thin
eissner's
corpuscIe
Krause end
buIb
Core
lat, transversely oriented
modified Schwann cells +
collagen fibers
Collagen fibers
$ite of entery of
nerve
Base of corpuscle Any site
Course of nerve
Spiral & gives branches bet
cells
Excessive branches
Termination of
nerve
Ball-like endings
unction
Touch mechanoreceptor
8ufflnl corpuscle 8ufflnl corpuscle
aclnlan aclnlan corpuscle corpuscle
aclnlan corpuscles ln skln vlscera
#uffini
corpuscIe
Pacinian
corpuscIe
$ite Soles & joint capsules ingers, external
genitalia,breast, CT of
pancreas, UB, skeletal m,
ligaments, joints,
periosteum
$kin IeveI eep in dermis eep in dermis &
hypodermis
$ize Small The largest
$hape Elongated Oval or rounded
LongitudinaI axis // to skin surface
#uffini
corpuscIe
Pacinian
corpuscIe
CapsuIe Thin Thin ( relative to its size)
Core Central axial core of
collagen fibers
20-30 concentric layers of flat cells
(schwann cells & fibroblasts) joined by
desmosomes & separated by collagen
fibers & tissue fluid
$ite of entery of
nerve
Side of corpuscle Any site
#uffini
corpuscIe
Pacinian
corpuscIe
Course of nerve Branch directly Run in long axis through granular
core
Termination of
nerve
Expanded end
unction:
proprioceptors
Sensitive to collagen
displacement
eep touch, pressure & vibration
roprlocepLors
for muscle sense
Pacinian
corpuscIe
uscIe
spindIe
GoIgi
Tendon
spindIe
Joint
receptor
Muscle splndle
Muscle splndle
ntrafusal fibers
!uclear bag
!uclear chain
fferent (sensory) endings
#rimary annulospiral
Secondary flower spray
Efferent (motor) fibers Camma fibers
Alpha motor fibers to extrafusal muscle fibers
Extrafusal fibers
capsule
ntrafusaI fibers NucIear bag NucIear chain
Numbers 2-4 4-8
Length Longer Shorter
idth Wider Narrower
id region (not striated not
contractiIe)
Expanded like a bag Not expanded
NucIei Many filling mid region Arranged in the form of a
chain
Afferent nerve endings Annulospiral Annulospiral &flower-spray
Efferent nerve fibers ine myelinated gamma fibers to both contractile
portions ME!
Primary annuIospiraI $econdary fIower-spray
Axon Thick Thinner
$ite On nucIear region of
aII intrafusaI fibers
Near nucIear region of
nucIear chain fibers onIy
#espond to
Amount and rate of strech
Amount of strech
AfferenL (sensory) endlngs
1endon splndle
(Colgl splndle)
Muscle spindle Golgi spindle
Name Stretch receptor Tension receptor
Site Between skeletal m.f. Between collagen f.
Core ntrafusal m. f. Collagen fibers
nnervation Motor& sensory Only sensory
1esL sllde
W Whlch ls Lrue concernlng Lhe Merkel's dlsc
a) CapsulaLed nerve endlng
b) resenL ln Lhe deep layer of epldermls of Lhe
skln
c) paln recepLor
d) Lenslon recepLor
b)
2)
WThis receptor is ...
WThe supporting ceIIs inside
this receptor are.....
3)1he polnLed recepLor
ls
number 1
represenLs
1he marked area by Lhe
red arrow represenLs

1
1hank ?ou