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Toxic Goitre Case

Mrs. Prema, a 35-year-old female, presents with a 6-year history of neck swelling and symptoms of hyperthyroidism, including breathlessness, palpitations, weight loss, and heat intolerance. She has been on carbimazole for 3 years and is diagnosed with toxic multi-nodular goitre without malignancy. The recommended treatment is total thyroidectomy with thyroxine replacement.
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0% found this document useful (0 votes)
30 views22 pages

Toxic Goitre Case

Mrs. Prema, a 35-year-old female, presents with a 6-year history of neck swelling and symptoms of hyperthyroidism, including breathlessness, palpitations, weight loss, and heat intolerance. She has been on carbimazole for 3 years and is diagnosed with toxic multi-nodular goitre without malignancy. The recommended treatment is total thyroidectomy with thyroxine replacement.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd

Case presentation

Venkatesh G
Thanga Rajeshwari K
Mrs Prema 35 year old female from Tharuvai who is a
homemaker came with chief complaints of
Swelling in front of neck for past 6 years
History of presenting illness
• The patient was apparently normal 6 years back suddenly
she noticed a swelling in front of neck which was insidious in
onset , slowly progressed to present size
• 3 years later the patient started developing,
• History of palpitation.
• History of breathlessness during exertion
• History of heat intolerance and excessive sweating
• History of loss of weight inspite of good appetite
• No History of tremors, irritability and sleep disturbance
• No history of double vision
• No history of difficulty in swallowing and hoarsenesss of
voice
• No history of cough with hemoptysis, bony pain
• She went to Tenkasi GH and started on medication for
hyperthyroidism
• Now the patient was referred to TVMCH for further
treatment
Past history
• The patient had no similar complaints in the past
• The patient is not a known case of diabetes mellitus,
hypertension, tuberculosis,bronchial asthma and epilepsy.
• No history of previous radiation exposure
• No history of previous thyroid surgery
Personal history
• The patient consumes mixed diet.
• She is not an alcoholic or smoker
• Regular bowel and bladder habits
• Normal sleep pattern

Menstrual history
• Patient attained menarche at 13 yrs .
• Regular 3/30 days cycle with moderate flow not associated with
pain and passage of clots
Treatment history
• Patient on Tab. Carbimazole for past 3 yrs
• Takes tablet regularly and on monthly follow-up in Tenkasi
GH

Family history

• No history of thyroid disorders among family members


present.
Summary
A 35 years old female Mrs Prema came with complaints of
swelling in front of the neck for past 6 years with history of
breathlessness on exertion, palpitation , weight loss, heat
intolerance 3 years back and started on tablet carbimazole.
General examination
• The patient is conscious , oriented,
• Moderately built and nourished
• No pallor/cyanosis/icterus/clubbing/pedal
edema/generalized lymphadenopathy
• No tremors present
• No eye signs
• Skin and oral cavity normal
Vitals
• Pulse rate: 75/min, regular rhythm, normal volume, no
specific character, no vessel wall thickening, no radio femoral
delay, felt equally on all peripheries
• Blood pressure: 120/80 mm Hg measured at right arm in
sitting position
• Respiratory rate: 18/min
• Temperature: 98.4 F
Local examination
Inspection
After getting consent from the patient ,the patient is exposed
upto nipples with neck extended examined in sitting position
with myself standing infront of the patient
• A butterfly shaped swelling of size 10*7cm in front of the neck
in thyroid region
• Extending superiorly 8cm below the mandible , inferiorly 4cm
above suprasternal notch, laterally upto anterior border of
sternocleidomastoid muscle on both sides
• The surface appears nodular with well defined margin
• Skin over the swelling normal, no scars, sinuses and dilated
veins.
• The swelling moves up with deglutition ,lower border of
swelling visible.
• Trachea appears to be in midline
Palpation
• Inspectory findings are confirmed
• No warmth or tenderness over the swelling
• A nodule of size 3*2 cm on right lobe and a nodule of size
2*2 cm on isthumus is palpable Surface nodular firm in
consistency, plane deep to deep fascia
• Lower border is palpable on deglutition
• Carotid pulsation felt equally on both sides
• Trachea is in midline , Kocher’s test negative
• No thrill felt
• No palpable cervical lymph node

Auscultation
• No bruit heard over the swelling
Examination of other system
• CVS: S1 S2 heard, no murmur
• RS: normal vesicular breath sounds heard
• Abdomen: soft, non tender, no organomegaly
• CNS: no focal neurological deficit
Diagnosis
A case of toxic multi nodular goitre with no features
suggestive of malignancy
Investigations
Routine investigations
• Complete blood count
• Coagulation profile
• Blood grouping and typing
• Urine- albumin, sugar, deposit
• Chest X ray
• ECG
• X ray neck AP / lateral view
• Sleeping pulse rate
• USG neck
• Thyroid function test
• USG guided FNAC
• Radio iodine uptake study
• Thyroid antibodies
• Indirect laryngoscopy
Treatment
Total thyroidectomy with thyroxine replacement
Thank you

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