Uploads by Mullan Alzheimer

Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease.

Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier. Bachmeier C, Mullan M, Paris D.

Depletion of CXCR2 inhibits γ-secretase activity and amyloid-β production in a murine model of Alzheimer's disease.

Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier.

Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier.

Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid.

Flavonoids lower Alzheimer's Aβ production via an NFκB dependent mechanism.

Identification of Plasma Biomarkers of TBI Outcome Using Proteomic Approaches in an APOE Mouse Model.

Anatabine lowers Alzheimer's Aβ production in vitro and in vivo

Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease.

Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons.

Institute targets in on Alzheimer's

Sarasota’s Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes

The Roskamp Institute

Roskamp Institute Scientists Discover Genetic and Biological Consequences of Substance Abuse

The Roskamp Institute funded by the Veterans Administration to find cellular mechanism implicated in the Gulf War Illnesses

The Roskamp Institute Battles Drug Abuse

The Traumatic Brain Injury Program at the Roskamp Institute

Roskamp Institute finds one of the genetic causes for Tourettes syndrome

Sarasota’s Roskamp Institute Welcomes U.S. Senator Bill Nelson

Dr. Mullan’s Alzheimer Research Identified Various Genetic Variations

Why work with Alzheimer's disease patients?

Dr. Mullan’s Alzheimer Research Involved Studying Brain Proteins

Family History of Alzheimer's disease - what does it mean?