Phoebe Dawn Guevarra BSN-IV GENERIC NAME Meropenem BRAND NAME Merrem CLASSIFICATI ON Antiinfective; carbapenem antibiotic INDICATION

Prescribed for bacterial infections like skin and skin structure infections, bacterial meningitis, serious nosocomial infections like septicaemia, febrile neutropenia, intraabdominal and pelvic infections. The medication inhibits cell wall synthesis in bacteria, and thereby leading to cell death. CONTRA INDICATION Contraindicated with hypersensitivity to carbapenem antibiotics ADVERSE RXN allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); seizures; severe or watery diarrhea; a skin rash; unusual tiredness or weakness; or unusual bleeding or bruising; nausea or vomiting; diarrhea or constipation; headache; or soreness, redness, or mild swelling at the injection site NURSING CONSIDERATION Assessment & Drug Effects Lab tests: Perform C&S tests prior to therapy. Monitor periodically liver and kidney function. Determine history of hypersensitivity reactions to other beta-lactams, cephalosporins, penicillins, or other drugs. Discontinue drug and immediately report S&S of hypersensitivity (see Appendix F). Report S&S of superinfection or pseudomembranous colitis (see Appendix F). Monitor for seizures especially in older adults and those with renal insufficiency. Patient & Family Education Learn S&S of

hypersensitivity, superinfection, and pseudomembranous colitis; report any of these to physician promptly. Do not breast feed while using this drug.