Professional Documents
Culture Documents
Brain Disorders
Teach New Learning Hypoperfusion
Patterns Hypo and Hyper sensitivity to stimuli
Different Learning Patterns
Behavioral Symptoms
Reduce/Eliminate Delayed Language
Symptoms Delayed Social Skills
Stereotypy
Minimize Exposure to Toxins
Make sure your physician only uses
antibiotics when necessary
Avoid pesticides (go organic)
Spread out vaccinations to reduce stress on
immune system
Check for metal toxicity to determine need
for chelation (toxic metal assay, porphyrins)
Treat Underlying Medical Illness
Immune Markers
Check for cell mediated immune activation
(neopterin/biopterin)
Check for Strep Titers
• ASO: Antistreptolysin O
• anti-DNase B: Anti-Deoxyribonuclease B
Immunoglobulin Subsets (Antibodies that respond to
bacteria, viruses, fungus, etc)
Vaccine Titers
Discuss Possible Treatments with your physician:
IVIG, Spironolactone
Treat Underlying Medical Illness
Oxidative Stress Markers (reduced
glutathione: found in every cell…helps
neutralize free radicals)
To identify need for Anti Oxidants
Decreased Methylation/transulfation
(fasting plasma cysteine or methionine)
To identify possible benefit of methyl B12
Treat Underlying Medical Illness
Evaluate and Treat GI Disorders
Nutrition
Diet
Medication (anti-inflammatory, steroids,
anti-fungals)
Reduce Hypoperfusion
HBOT?
Teach New Learning Patterns
Evaluate need for modified sensory input
Visual
Auditory
Tactual
ABA: Applied Behavior Analysis
“30 years of research demonstrated the efficacy of
Applied Behavioral methods in reducing inappropriate
behavior and in increasing communication, learning
and appropriate social behavior”
Surgeon General, 1999
ABA and Biomed working together
Because a healthy child sleeps better, feels better and can learn better!
Why would a behaviorist care
about biomedical interventions?
1990: Andrew was diagnosed with Celiac…
we placed him on a diet and he recovered
within a year!
1992: I began to notice a pattern of children
with extremely high use of antibiotics! This
must be leading to some abnormal flora!
1993: Emily had fungus on her nails…
treated with antifungals, her behavior
changed drastically!
Preliminary Outcome Study:1996
79 children
63 boys 16 girls
Average age at intake: 39.1 months
44 children 35 children
IQ Standard Score
95 High Intensity
90
85
80
75 Low Intensity
70
1 2
Pre-Treatment Post Treatment
High Intensity
90
85
80
75
70
Low Intensity
65
60
1 2
Pre-Treatment Post Treatment
Normal Cognitive Functioning
WPPSI: Pre- & Post-ABA Early Intervention
130
Pre-Test
120
Post-Test
110
100
90
80
Intelligence Quotient
70
60
50
40
30
20
10
0
20 22 27 29 29 30 30 31 31 31 32 34 38
Average Therapy Hours Per Week
Why didn’t we publish this?
1996 Outcome Study Confounding Variable:
• A higher percentage of children in the
high intensity group were receiving
biomedical interventions!
• Was the improvement in IQ and
adaptive skills due to ABA or due to
the medical interventions or a
combination???
THE KEY IS TO IDENTIFY WHAT IS
CAUSING AUTISM IN YOUR CHILD!
TREAT THE UNDERLYING CAUSE…
AND THEN USE ABA TO TEACH
YOUR CHILD ALL THE SKILLS HE
DIDN’T LEARN WHEN HE WAS MOST
AFFECTED!
ALL CHILDREN NEED AND BENEFIT
FROM ABA!
1987: Behavioral Treatment and Normal
Educational and Intellectual Functioning in
Young Autistic Children
Experimental Group: N=19
47%
40 hours/wk
Recovered!
3 yrs
10 hours/wk 10 hours/wk
3 2% UCLA/NPI
yrs Recovered
3 yrs
Control Group 1: N=20 Control Group 2: N=20
Children with Autism DO Recover!
There is NO magic pill
It is hard work and can take a long time
GFCF
350 Diflucan +
Nystatin +
300 Probiotics
250
Frequency
200
150
100
50
0
Feb Mar April May June July Aug Sept Oct Nov Dec Jan Feb
Months
Tantrums Non-Compliance Screaming
200
150
100
50
0
Nov-03 Dec-03 Jan-04 Feb-04 Mar-04 Apr-04 May-04 Jun-04
Months
DR
D.R.: Cumulative Skills
1000
800
600
400
200
0
Nov-03 Dec-03 Jan-04 Feb-04 Mar-04 Apr-04 May-04 Jun-04
Months
DR
D.R.: Stereotypy per month
400
300
200
100
0
Nov Dec Jan Feb Mar April May June
M onths
DR
Diet +
100 Feingold Diet
90 +
80
Rotation diet
70
60
50
40
30
Month
20
10
0
Nov Dec Jan Feb Mar April May June
Months
DR
Emma
Diagnosis: Asperger’s Syndrome
Intake:
Age: 3.4
Deficits: poor eye contact, extensive vocabulary but did not use
language with peers, self-isolated at school, severe tantrums, non
compliance and aggression with family, visual self-stimulatory
behaviors, severe ritualistic behavior, no Theory of Mind
Treatment:
10 months with CARD
Average intensity of 10 hours/week
Lexapro
Pro DHA and CorOmega
Exit:
Age: 4.2
In typical kindergarten with no aide
Initiated conversations with peers, many friends, no tantrums or
aggression, very advanced in academic skills and very popular in
school
Emma: Challenging Behaviors per month
0
April May June July Aug Sept Oct Nov Dec
Months
Tantrums Non-Compliance Ritual SSB
Emma
Emma: New Skills per month
120
New Skills per Month
100
80
60
40
20
0
Mar 04 April 04 May 04 June 04 July 04 Aug 04 Sept 04 Oct 04 Nov 04 Dec 04
Months Emma
A. D.
Diagnosis: Autism
Intake:
Age: 2.11
Deficits: had 3-4 word utterances but no spontaneous language, self-
isolated around peers, no safety awareness, toe walking, licking hands,
had difficulty inhibiting responses and would often touch people’s hair or
clothing.
Treatment:
3 year with CARD
Average intensity of 25 hours/week
Anti-fungals
Chelation
Exit:
Age: 5.11
In typical kindergarten without aide
Initiates, joins, transitions conversations with peers, has many friends,
good understanding of others perspectives, no challenging or self-
stimulatory behaviors present. Normal range on all exit testing (IQ,
language, TOM, EF)
A.D.: Challenging Behaviors per month
ABA +
ABA
Antifungal +
14 Chelation
Frequency per Hour
12
10
0
June
Jan
June
Oct
Feb
March
May
July
Nov
Dec
May
Sept
April
Aug
M onth AD
Elopement Fidgeting Leaning
Running Grabbing Screaming
A.D.: New Skills per month
ABA +
ABA
Antifungal +
New Skills per Month 250 Chelation
200
150
100
50
0
June
Feb
March
June
Oct
Jan
May
Dec
Nov
Sept
April
Aug
July
M onth AD
111-TEM
- 2 year old male
- Completed 80 dives in 14 weeks
- Mother reported tremendous gains in
language and socialization; significant
changes were also noted by examiner
during post-testing.
- Supervisor reported that participant
acquired many skills since starting the
study.
ADOS
Lower scores are better
ADOS
14
12
10
8 Pretest
Total Score
Post-test
Autism Spectrum Cutoff
6 Autism Cutoff
4
Significant improvement on score Commication and
Socialization score on the ADOS; both in autism spectrum
range
2
0
ADOS Com ADOS Soc ADOS Tot
ADOS Area
ABC
Lower is better
Aberrant Behavior Checklist
120
100
80
Irritability/Agitation
Lethargic/Withdrawal
Score by Area
20
0
1
k1
k2
k3
k4
k5
k6
k7
k8
k9
n
k1
k1
k1
k1
k1
BL
BL
io
ee
ee
ee
ee
ee
ee
ee
ee
ee
et
ee
ee
ee
ee
ee
W
pl
W
m
Co
Week
What do we learn from these
Case Studies?
A variety of medical interventions worked
for these children
Each child benefited from a different type
of intervention
Autism is a “Spectrum Disorder”…children
with Autism are very different from each
other!
Will these interventions work for your
child?
We simply don’t know!
Next Steps in the Medical
Treatment of Autism
We need to do studies that show changes
across groups of children
Exp: all children exposed to MB12 improved
This is difficult (if not impossible) because the
children are all different from each other!
Therefore, we need to find PHENOTYPES
of Autism
What type of child does well with MB12?
Which children benefit from chelation?
Who needs a course of HBOT?
What you can do as a parent
Look for biomarkers that indicate what
medical treatment your child needs
Understand the lab results your physician
orders
Try one intervention at a time
Measure the change in behavior with each
intervention
Stick with a plan!
DO ABA! IT WORKS FOR ALL KIDS
What is Applied Behavior Analysis
ABA is based on the principles of
Behavior Behavior
What behavior do we want to change?
Deficits Excesses
Language Self Stimulatory Behs
Play Maladaptive Behs
Social Skills • Tantrums
• Aggression
Theory of Mind
• Noncompliance
Executive Functions
Teaching
Procedures Function-Based Emergency
Treatment Interventions
Evaluation of Tx
Effectiveness
(Data Collection & Analysis)
Generalization &
Maintenance
Shaping Knowledge
Through Individualized Life
Learning Systems
(SKILLS)
What is SKILLS?
E-Learning
Trains “how to” do ABA (the techniques)
SKILLS Index
Every child is different…what do I teach my
child?
Assesses child’s known and unknown skills
through questions directly tied to CARD I
Curricula
CARD I Curricula
Provides “what to” teach
Skill Repertoire Instruction
Discrete Trial Training
Prompting
Shaping
Chaining
Reinforcement
Errorless Learning
Natural Environment Training
Fluency Based Instruction
School
Skills
Executive Social
Cognition
Functions Skills
Motor
Language Play Adaptive
Skills
The CARD Curriculum Language
Safety
Safety Awareness
Community Safety Equipment
Shopping
Restaurant Readiness
Motor Curriculum
Motor
Oral
Oral Motor
2.
3.
4.
Visual Form Constancy
What is added to the first picture to make the second picture?
Motor
1. First Picture Second Picture
to
to
to
Visual Figure-Ground
Discrimination Motor
1.
Deception Senses
Sensory
Beliefs Perspectiv
e Taking
Thinking Desires
Preference
Knowing
s
Social
Social Skills Curriculum Skills
Social Language
Greetings and Salutations
Non-Vocal Social Behavior
Eye Contact Social ID Questions
Non-Vocal
Non-Vocal Imitation Prosody
Body Language
Absurdities Social& Facial Regulating Others
Expressions
Behavior
FiguresGestures
of Speech Conversational Audience
to Regulate Social Interaction
Social Social Interaction
HumorAbsurdities
and Jokes Physical Context
Language
of Conversation
Apologizing
Listening to Conversation
What’s Wrong?
Assertiveness
Initiating Conversation
Compliments
Joining Conversation
Group Cooperation
Maintaining & Negotiation
Conversation
Group Related Skills Social
Gaining Attention
RespondingRelated
in Unison Social Skills Repairing Conversation
Introductions
Group Discussion Interaction
Transitioning Topics of Conversation
Skills Levels of Friendship
Ending Conversation
Sharing & Turn Taking
Social Rules SelfLending
Esteem & Borrowing
Compliance Dealing with Conflict
Social
Following Rules Self Esteem
Positive Self-Statements
Rules
Community Rules Social Context Winning & Losing
Politeness & Manners Social
Responding to SocialConstructive
Cues Criticism
LearningContext
Through Observation
The CARD Curriculum Executive
What is Executive Function? Functions
Process that underlies goal
directed behavior
Goal Directed Behavior Involves…
Visualizing situation
Identifying desired objective
Determining plan to meet
objective
Monitoring progress to goal
Inhibiting distractions
Executive Functions
Curriculum Executive
Inhibition Flexibility/
Functions
Waiting, Set-Shifting
Physical / Motor,
Non-Social,
Vocal,
Inhibition Social,
Flexibility
Planning Pencil / Paper
Social –Cognitive, Attention
Task / Social Situational Social Orienting,
Goal Setting, Previewing, Joint Attention,
Task Initiation, Sustained, Divided, &
Monitoring Progress, Alternating Attention,
Time Management,
Planning
Organizing Materials, EF Determining Saliency,
Attention
Depth of Processing,
Using a Planner, Paraphrasing,
Self-Organization Task Persistence
Meta-Cognition
Meta-
Meta-cognitive Planning,
Cognitive Memory
Self-Evaluation, Meta-memory, Problem
Problem
Planning Memory
Associative,
Self-Monitoring of Attention, Solving Visual, Spatial,
Emotions, Reinforcement Control, Solving
Non-Social, Auditory, Episodic,
Study Skills, & Flexibility Social Working
Children’s Color Trail Test
Stroop Activities
Summary
A good ABA program requires good
assessment to determine exactly what your
child needs to learn!
A good ABA program needs a lot of hours!
Don’t do 5 hours of ABA when 40 hours
are recommended! This is like taking 5 mgs
of a drug that has shown to be effective at
40 mgs! It wont work!
A 4 year progression
Year 1:
Child entering at age 2-3
25 hours per week building to 40 hours
Allocation of Hours
Emphasis on
• Building a relationship with child 40
• Replacing challenging behaviors with 30
functional communication 20
Mands (Requests) 10
Tacts (labels) 0
Year Year Year Year
• Receptive identification (objects, 1 2 3 4
actions, body parts, colors, shapes) Home-based School-based
• Receptive instructions
• Verbal and Non-verbal Imitation
• Identical Matching
• Play Skills (toy play)
• Adaptive Skills (toilet training)
• Fine and Gross Motor
• Dietary restrictions/medical compliance
A 4 year progression
Year 2:
Child age 3-4
40 hours (in home with partial transition to school)
Emphasis on
• Building Expressive Language
Objects, Actions, Attributes, Prepositions, Pronouns Allocation of Hours
Categories, Functions, Occupations, Locations
• Beginning Conversation 40
Intraverbals 30
Reciprocal Statements 20
Asking Questions 10
• Developing Observational Learning 0
I See Year Year Year Year
Sequences 1 2 3 4
Tell me about/Describe Home-based School-based
• Emotion Recognition
• Inferring others desires
• Play Skills (functional pretend, symbolic, imaginary)
• Adaptive Skills (dressing, grooming, feeding)
• Fine and Gross Motor
• Sharing and Turn taking
• Attention (dual and divided)
A 4 year progression
Year 3:
Child age 4-5
40 hours (20 hours at home; 20 hours at school)
Sample Programs
• Advanced Language Concepts
Pragmatic Language
Maintaining Conversation (topic initiation, repair,
maintenance) Allocation of Hours
• Meta and Social Cognition
Identifying and Managing own emotions 40
Understanding other’s Perspectives, Knowledge 30
and Beliefs 20
Inferences 10
• Executive Function 0
Year Year Year Year
Attention Saliency
1 2 3 4
Flexibility with Routines
Home-based School-based
Inhibition and Self Monitoring
Planning
• Social Skills
Levels of Friendship
Recognizing Social Cues
• Problem Solving
• Play Skills (peer play dates)
• Adaptive Skills
• Fine and Gross Motor
A 4 year progression
Year 4:
Child age 5-6
40 hours (10 hours at home; 30
hours in school and fading
services) Allocation of Hours
Emphasis on
40
• Teacher and Parent training 30
• School Skills 20
Listening and Reading 10
comprehension
0
Math and Problem Solving Year Year Year Year
• Advanced Social Skills 1 2 3 4
Detecting Sarcasm Home-based School-based
Understanding Deception
Group Skills
• Continued Self Regulation
Self Esteem and Confidence
Task and Social Planning