DRUGS INDICAT ACTION SIDE/AD NURSING PATIENT

ION VERSE CONSIDERA TEACHINGS

EFFECT TION
S

Generic treatment Inhibits RNA Various  Assess lab  PO route: give

Name: of synthesis, skin exams with meals to
ISONIAZID pulmonar decreases eruptions,
before decrease GI
fever,
y tubercle treatment symptoms,
Therapeuti lymphade
tuberculos bacilli to detect absorption is
c class: nop
Anti-TB is. replication athy and resistance. better when taken
drugs vasculitis, on empty
GI  Assess CNS stomach, 1 hour
Dosage: disturbanc
often, before or after
es,
300 mg OD liver hepatic meals.
dysfunctio status and
ns, visual  Instruct patient
peripheral disturbances that compliance
neuropath with dosage
.
y schedules for
and duration is
anemia necessary to gain
and/or benefits
visual .
defect.
These
events
have also
been
reported
in the
absence
ot a
diagnosis
of optic or
retrobulba
r neuritis.
DRUGS INDICAT ACTION SIDE/AD NURSING PATIENT
ION VERSE CONSIDERA TEACHINGS
EFFECT TION
S

Generic Temporar May cause Hemolytic  Assess  Tell patient not to

Name: y relief of analgesia by anemia, patients pain use drug fever
Paracetam pain and inhibiting CNS leukopeni
or that’s higher than
ol a,
discomfor prostaglandin temperature 103.1 F
neutropen
t for synthesis
ia, before  Warn patient that
headache, panyctope high doses and
beginning
fever, nia, unsupervised long
Therapeuti treatment term use can cause
c class: cold, flu, thrombos
liver damage
Anti- minor ytopenia,
 Be alert for
pyretic liver
muscular signs of  tell patient keep
damage,
aches, tract of daily oral
Dosage: jaundice, adverse
overexerti drug intake
hypoglyce reactions.
1 tab 650 on. mia, rash
mg TID
DRUGS INDICAT ACTION SIDE/AD NURSING PATIENT
ION VERSE CONSIDERA TEACHINGS
EFFECT TION
S

Generic treatment Inhibits DNA- CNS:head  Administer  Teach client to take

Name: of dependent ache, on an empty drug in a single daily
Rifampacin pulmonar RNA stomach, 1 hr dose. Take on an
fatigue, before or 2 hr empty stomach, 1 hr
y polymerase, after meals. before or 2 hrs after
drowsines
tuberculos thus meals.
s,
Therapeuti is. impairing RNA behavioral  Administer in  Inform client
c class: synthesis a single daily
changes, to take this drug
Anti-TB dose.
(bactericidal). dizziness, regularly; avoid
agent mental  Consult missing any doses;
pharmacist do not discontinue
confusion,
Dosage: for rifamoin this drug without
generalize consulting the
d suspension
600 mg health care provider.
numbness, for patients
P.O. or
unable to  Tell client to
ataxia.
swallow have periodic
I.V. daily capsules.
CV: sh o medical chechups,
in single
ck. including eye
dose 1  Prepare
EENT:vis examinations and
hour before patient for blood test, to
ual the reddish-
or 2 hours evaluate the drug
after meals. orange effects.
disturbanc coloring of
es, body fluids  Inform client
exudative (urine, sweat, that he may
conjunctiv sputum, experience the
itis. tears, feces, drug’s side effects
saliva); soft (especially the red
GI:epi contact colored secrection)
gastric lenses may
 Instruct client
be
to see his physician
permanently
distress, if he experience
stained;
anorexia, fever, chills, muscle
advise
nausea, patients not
and bone pain,
vomiting, excessive tiredness
to wear them
abdominal or weakness, loss of
during
appetite, N/V,
pain, therapy. yellowing of
diarrhea, eyes/skin, unusual
flatulence,  Warning: bleeding or bruising,
arrange for
 follow-up skin rash or itching.
sore visits for
liver and  Instruct client
mouth and to remove contact
tongue, renal
function lenses as they may
pseudome discolor
tests, CBC,
mbranou
and
s colitis, ophthalmolo
gic
examinations
.

DRUGS INDICAT ACTION SIDE/ADVER NURSING PATIENT

ION SE EFFECTS CONSIDERATI TEACHING
ON S

Generic Ethambuto Ethambutol is  loss of  Assess  Teach client

Name: l eliminates bacteriostatic appetite patient for to take drug
certain against actively infection in a single
Ethambuto  upset (appearance of daily dose.
l bacteria growing TB stomach wounds, sputum, Take on an
that cause bacilli, it works VS, urine and empty
Therapeuti tuberculosi by obstructing  vomitin stool and WBC.) stomach, 1
c class: s (TB). It is the formation g at beginning and hr before or
Anti-TB used with of cell wall.  numbne during therapy. 2 hrs after
agent other Mycolic acids ss and meals.
 Obtain
medicines attach to the tingling in specimens before  Infor
Dosage: to treat 5′-hydroxyl the hands or initiating therapy. m client to
tuberculosi groups of D- fee Take drug as take this
100 mg
P.O. s and to arabinose indicated. drug
 optic
prevent residues of regularly;
neuritis–  Not to be avoid
. you from arabinogalacta blurring of given to children missing any
giving the n and form vision 6 years below doses; do
infection to mycolyl- due to optic not
others. arabinogalacta neuritis discontinue
n- this drug
 Provide
peptidoglycan without
supplemental
complex in the consulting
vitamin A. if not
cell wall. It the health
contraindicated
care
disrupts
provider.
arabinogalacta 
n synthesis by
inhibiting the
enzyme
arabinosyl
transferase.
Disruption of
the
arabinogalacta
n synthesis
inhibits the
formation of
this complex
and leads to
increased
permeability of
the cell wall.).
DRUGS INDICAT ACTION SIDE/ADVER NURSING PATIENT
ION SE EFFECTS CONSIDERATI TEACHING
ON S

Generic Pyrazinami Pyrazinamide is The most  Patients started  Patien

Name: de is a prodrug that common on ts should be
Pyrazinami indicated stops the (approximately pyrazinamide instructed to
for the growth of 1%) side effect should have notify their
de
of baseline serum physicians
initial Mycobacteriu
pyrazinamide uric acid and promptly if
Therapeuti treatment m they
is joint pains liver function
c class: of active tuberculosis.pe (arthralgia), determinations. experience
Anti-TB tubercuIosi rmeability of but this is not Those patients any of the
agent s in adults the cell wall.). usually so with preexisting following:
and severe that Iiver disease or fever, loss of
Dosage: children patients need those at appetite,
to stop taking malaise,
when increased risk
Tablets USP the nausea and
combined for drug related
500 mg pyrazinamide. vomiting,
hepatitis (e.g.,
with other darkened
The arthralgia alcohol abusers)
antitubercu urine,
can be should be
-lous yellowish
distressing to followed
discoloratio
agents. patients, but is closely. n of the skin
(The never harmful.
and eyes,
current  Pyrazinamide pain or
recommen The most should be swelling of
dation of dangerous side discontinued the joints.
effect of and not be
the CDC for
pyrazinamide resumed if signs
drug-
is of hepatocel-
susceptible hepatotoxicity, lular damage or
disease is which is dose hyperuricemia
to use a related accompanied by
six-month an acute gouty
regimen arthritis appear.
for initial
treatment
of active
tuberculosi
s,
consisting
of
isoniazid,
rifampin
and
pyrazinami
de given
for 2
months,
followed
by isoniazid
and
rifampin
for 4
months.