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NAME: Mrs. M
NATIONALITY: Filipino
Endometrial adenocarsinoma
HEALTH HISTORY
Two months prior to admission, patient had another episode consult to the OB
Gyne when curettage done revealed Endometrial Adenocarsinoma referred hence
admitted for TAHBSO with BLND
A Myoma is a solid tumor made of fibrous tissue, hence it is often called a 'fibroid'
tumor. Myomas vary in size and number, are most often slow-growing and usually cause no
symptoms. Myomas that do not produce symptoms do not need to be treated. Approximately
25% of myomas will cause symptoms and need medical treatment.
Myomas may grow as a single nodule or in clusters and may range in size from 1 mm to
more than 20 cm in diameter. Myomas are the most frequently diagnosed tumor of the female
pelvis and the most common reason for a woman to have a hysterectomy. Although they are
often referred to as tumors, they are not cancerous.
The cause of myomas has not actually been determined, but most myomas develop in
women during their reproductive years. Myomas do not develop before the body begins
producing estrogen. Myomas tend to grow very quickly during pregnancy when the body is
producing extra estrogen. Once menopause has begun, myomas generally stop growing and can
begin to shrink due to the loss of estrogen.
Until recently, hysterectomy was the preferred option for treating symptomatic fibroids.
Now, however, there are a number of uterine fibroid treatments including the noninvasive,
outpatientMR guided Focused Ultrasound myoma treatment.
Clinical Manifestation
• TAHBSO
• Hysterectomy
• Myomecomy
Anatomy and Physiology
Ovaries
The two ovaries are small organs suspended in the pelvic cavity by ligaments. The
suspensory ligament extends from each ovary to the lateral body wall, and the ovarian ligament
attaches the ovary to the superior margin of the uterus. In addition, the ovaries are attached to the
posterior surface of the broad ligament by folds of the peritoneum called the mesovarium. The
ovarian arteries, veins, and nerves transverse the suspensory ligament and enter the ovary
through the mesovarium.
A layer of visceral peritoneum covers the surface of the ovary. The outer part of the
ovary is made up of dense connective tissue and contains the ovarian follicles. Each of the
ovarian follicles contains an oocyte, the female sex cell. Loose connective tissue makes up the
inner part of the ovary, where blood vessels, lymphatic vessels, and nerves are located.
Uterine Tubes
A uterine tube, fallopian tube, or oviduct (named after the italian anatomist, Gabriele
Fallopio) is associated with each ovary. The uterine tubes extend from the area of the ovaries to
the uterus. The open directly into the peritoneal cavity near each ovary and receive an oocyte.
The opening of each uterine tube is surrounded by long, thin processes called fimbriae.
The fimbriae nearly surround the surface of the ovary. As a result, as soon as the oocyte
is ovulated, it comes into contact with the surface of the fimbriae. Cilia on the fimbriae surface
sweep the oocyte into the uterine tube. Fertilization usually occurs in the part of the uterine tube
near the ovary known as the ampulla.
Uterus
The uterus is as big as the size of a medium-sized pear. It is oriented in the pelvic cavity
with the larger, rounded portion directed superiorly. The part of the uterus superior to the
entrance of the fallopian tubes is called the fundus. The main part of the uterus is called the body,
and the narrower part is termed the cervix and is directed inferiorly. Internally, the uterine cavity
in the fundus and uterine body continues through the cervix as the cervical canal, which opens
into the vagina. The cervical canal is lined by mucous glands.
The Uterine wall is composed of three layers: a serous layer or perimetrium of the uterus,
consists of smooth muscle is quite thick and accounts for the bulk of the uterine wall. The inner
most layer of the uterus is called the endometrium. The endometrium consists of simple
columnar epithelium tissues with an underlying connective tissue layer. Simple tubular glands,
called enometrial glands, are formed by folds of the endometrium. The superficial part os the
endometrium is sloughed off during menstruation.
The uterus is supported by the broad ligament and the round ligament. In addition to
these ligaments that support the uterus, much support is provided inferiourly to the uterus by
skeletal muscles of the pelvic floor. If ligaments that suppor the uterus or the muscles of the
pelvic floor are weakened such as in childbirth, the uterus can extend inferiorly into the vagina, a
condition termed as a prolapsed uterus. Severe cases require surgical correction.
Vagina
The vagina is the female organ of copulation and functions to receive the penis during
intercourse. It also allows menstrual flow and childbirth. The vagina extends from the uterus to
outside the body. The superior portion of the vagina is attached to the sides of the cervix so that a
part of the cervix extends into the vagina.
The wall of the vagina consists of an outer muscular layer and an inner mucous layer.
The muscular layer is smooth muscle and contains many elastic fibers. Thus the vagina can
increase in size to accommodate the penis during intercourse, and it can stretch greatly during
childbirth. The mucous membrane is moist stratified squamous epitheliam that forms a protective
surface layer. Lubricating fluid passes through the vaginal epithelium into the vagina.
In young females, the vaginal opening is covered by a thin mucous membrane known as the
hymen. The hymen can completely close the vaginal oriface in which case it must be removed to
allow menstrual flow. More commonly, the hymen is perforated by one or several holes. The
openings of the hymen are usually greatly enlarged during the first sexual intercourse. The
hymen can also be perforated during a variety of activities including strenuous exercise. The
condition of the hymen is therefore not a reliable indicator of virginity.
The clitoris consists of a shaft and a distal glans. Like the glans penis, the clitoris is well
supplied with sensory receptors, and it is made up of erectile tissue. An additional erectile tissue
is located on either side of the vaginal opening.
On each side of the vestibule, between the vaginal opening and the labia minora, are openings of
the greater vestibular glands. These glands produce a lubricating fluid that helps maintin the
moistness of the vestibule.
Lateral to the labia minor are two prominent rounded folds of skin called the labia
majora. The two labia majora unite anteriorly at the elevation of tissue over thepubic symphysis
calle dthe mons pubis. The lateral surfaces of the labia majora and the surface of the mons pubis
are covered with coarse hair. The medial surfaces of the labia minora are covered with numerous
sebaceous and sweat glands. The space between the labia minor is called the pudendal cleft.
Most of the time, the labia minora are in contact with each other across the midline , closing the
pudendal cleft and covering the deeper structures within the vestibule.
The region between the vagina and the anus is the clinical perineum. The skin and muscle
of this region can tear during childbirth. To preven such tearing, an incision called an episiotomy
is sometimes made in the clinical perineum. Traditionally, this clean, straight incision is thought
to result in less injury, and less trouble in healing, and less pain. However, many studies indicate
that there is less injury and pain when no episiotomy is performed.
PATHOPHYSIOLOGY
Precipitating Factors:
-High fat diet
Predisposing -Obesity
Factors: -Anxiety/Stress
-Age -Oral Contraceptives or
Etiology:
-Gender Unknow
-Heredity -Hormone replacement
-Early therapy
Menarche -Luteal Insufficiency
Estrogen Dominance or
increase in Estrogen -Coffee/ Caffeine intake
production
Proliferation of
cells in uterus* S/sx:
-Swelling of breasts
-Depression
-Loss of sex Drive
Overgrowth the -Dysmenorrhea
endometrial lining
Myoma:
Development of
uterine fibroid
Interference in the
vascular supply
Degeneration of
the interior part of S/sx:
-hypermenorrhea
fibroid -Abnormal bleeding
PHYSICAL ASSESSMENT
BODY PARTS TECHNIQUE FINDINGS INTERPRET
ATION
HEAD
• Hair Inspection Black in color Normal
No lice
Normal
11GORDON
• Fingernails BEFORE
Inspection DURING
Clean and ANALYSI INTERPRETATION
Normal
PATTERN properly cut S
1.Health Health is PalpationI am not Slightly poorHealth is Due Theto patient
present is not
Perception important, capillary
knowledgeable refill
a condition
knowledgeable
because this is about my disease condition about her condition
the only one that all I know is that of but she is willing to
I have to function this operation will physical, undergo all the
• Shoulder as well to giveInspection
my help me symmetrical
to live and
mental Normal
procedures for her
family comfort longer pale in color.
and betterment
and away from social Due to present
illness. A good well condition
• Heart health canAuscultation
take 90 bpm being and Normal
me away from the
illness because absence
• Palpation
Thorax and hospitalization
lungs is No tendernessof Normal
expensive to No wheezingdisease
avoid for itAuscultation
I keep sound Normal
myself health.
2.Nutritional He eats 3 times a He eat 3 times a Hepersen The pts.
Metabolic Pattern day, having snack day with snack sitivy to Nutritional
in the afternoon in the afternoon aquatic metabolic
• Abdomen Inspection and has
with his family.
Flat, Symmetrical
a food foods
Duepatterns
to present
in
He has food slightly
allergies to fish. pale in condition
general is all good
allergies to fish, He is in soft color
diet because she eats
as of his food diet Normoactive
and he drink 3-4 the minimum
consists ofAuscultation
meat sound
glasses of water req’ts of food that
more than 3 in a day,No tenderness
vitamin Normal
is essential to
Palpation B complexResonant
times in a week as survival
and vegetables ordered. Normal
sometimes. He
drink 7-8 glasses Normal
of water in a day
and sometimes
soft drinks.
Percussion
LOWER Inspection Symmetrical Normal
EXTREMITIES
3.Elimination Pattern He voids 6 times He voids Pale in color Before:6
5 times There are no
in a day and in a day and in During:5 Duesignificant
to present
yellowish inPalpation
color normal color no alteration on her
condition
have no foul odor. foul odor. He elimination
His bowel bowel 1 times a pattern
movement 2 day in normal
• Legs times in a day,
Inspection color andslightly pale. Due to present
normal in color. consistent. condition
10.Copping stress He spends his time to his family and internali Pt. M uses
Management relatives to coping up from stressed. zation internalization as
her overall stress
mgtter
11.Values belief He is active member of Pentecost and She Religious in nature
pattern they go to church every Sunday. keeps
praying
to god
even
she’s not
attendin
g
Sunday
mass
Course in the Ward
12/06/10
Doctor’s order Rationale
Please admit under Dr. Melchor dela For regal purposes
Cruz secure consent for admission and
management
Monitor BP, TPR for 4o For baseine data
Clear liquid then NPO In preparation for operation
Diagnostic: For baseline data
fbs
IVF D5LRS 1Lx8o on call medication To maintain electrolytes
Cefazolin 1 gram IV ANST
For TAHBSO with BLND on Nov7, Removal of the anomaly
2010
Secure consent For regal purposes
12/06/2010
8:50PM
anesthesia note preparation of the operation
Blood Chemistry
Diagnostic Indications or Normal Analysis and
Results
Procedure Purpose Values interpretation
Glucose ; RBS To measure the 101 <140 Normal count.
amount of mg/dl It means the
glucose in the amount of
blood right at glucose in the
the time of blood is
sample sufficient for
collection energy
production and
also not
excessive to
cause
hyperglycemia.
Indicated
insulin
(pancreatic)
function is
functioning to
its optimum.
Creatinine To evaluate 0.8 0.4-1.4 Normal. It
kidney mg/dl means toxic
function. substances in
the body are
maintained in
normal amount
and signifies
the kidneys are
functioning
normally with
accordance to
its filtration
and excretion
of toxic
substances.
Result also
indicate
normal pH of
blood is
maintained.
ENDOMETRIAL ADENOCARCINOMA
Drug Study
Side Effect/
Generic Name
Classification Indication Action Adverse Nursing Consideration
(Brand Name)
Reaction
Brand Name: urinary tract First generation • Assess patient for infection (vital
Ancef Therapeutic: infections cephalosporin Seizures (high signs; appearance of surgical site,
Anti-infectives anti-infective doses), diarrhea, urine; WBC) at beginning and
Generic Name: drug that inhibits during therapy.
Cefazolin cell-wall nausea, • Before initiating therapy, obtain a
Sodium synthesis, history to determine previous use of
Pharmacologic: promoting vomiting, and reactions to penicillins or
osmotic cephalosphorins. Persons with a
First generation cramps,
instability; negative history of penicillin
cephalosphorins usually Rashes, urticaria sensitivity may still have an allergic
bactericidal. response.
Allergic • Obtain specimens for culture and
sensitivity before initiating therapy.
reactions • Observe patient for signs and
including symptoms of anaphylaxis (rash,
pruritis, laryngeal edema,
Anaphylaxis and wheezing). Discontinue drug and
notify physician or other health care
Serum sickness, professional immediately if these
superinfection problems occur. Keep epinephrine,
an antihistamine, and resuscitation
equipment close by in case of
anaphylactic reaction.
Brand Name: 10 mg / amp Opioid Itching, burning,
Nubain Narcotic agonist- PRN analgesics. Binds urticaria,
antagonist with opiate Nausea,
Generic Name: analgesic Receptors in the vomiting,
Nalbuphine CNS, altering cramps,
Hydrochloride perception of dyspepsia, bitter
and emotional taste, dry mouth
response to pain.