Distinct areas in Hypothalamus
Optic chiasm right next to pituitary. CN III, IV, VI.
Posterior pituitary only stores hormones.
PRL will be seen in pituitary adenoma
Lesion at thyroid and TSH gets no response.
Thyrotoxicosis is a type hyperthyroidism
FSH and LH:
Most pituitary hormones have diurnal variation. Spike in early morning: this is why we do 24 hour urine sample.
PCOS = polycystic ovarian syndrome
Hematuria: interferes with 24 hour urine test.
Emesis happens in sympathetic state. Body produces ADH in sympathetic state.
Trying to keep fluid in the system.
DM: different is that one is nephrogenic: lesion at level of KI or neurogenic, lesion is at level of brain.
SIADH: syndrome of inappropriate ADH.
Headaches: anything over 10mm (macro) starts pressing on structure
*Signs and symptoms of a mass lesion, such as headaches, visual field defects are the biggest clue to pituitary tumour.
If 1 hormone: it is at level of gland.
Bilateral hemianopia: loss of vision on outer halves of visual field
Rare for pituitary lesion to only effect ECTH.
\u201cpituitary dwarfism\u201d is from birth
Loss of muscle mass and strength in isolated GH deficiency.
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