Basic knowledge of the treatments used in the management of breast cancer Knowledge of the basic concepts of cell proliferation,

, differentiation and cell death Knowledge of the basic concepts of the pathology of cancers: classification, epidemiology, aetiology, spread and clinical effects of tumours Knowledge of the genetic basis of cancer including: sporadic and inherited cancers, predisposition to cancers, chromosomal abnormalities, somatic mutations, oncogenes, tumours suppressor genes, replication error repair genes and dna repair genes Knowledge of the methods used to test for the presence of HER2 (immunocytochemistry) Knowledge of the structure and function of the breast Describe the lymphatic drainage of the breast and upper limb Basic knowledge of the role of depression, helplessness, hopelessness and despair in chronic lifethreatening disease Knowledge of the concept of illness beliefs (illness representation) Knowledge of the basic concepts of the pathology of cancers: classification, epidemiology, aetiology, spread and clinical effects of tumours