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  • 9.01 Study Questions: Class 16 (CNS Development, Continued)

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    This document contains 9 study questions for a class on central nervous system development. The questions cover topics like the two types of neuronal migration in development, the "inside-out pattern" of neocortex migration, the external granular layer of the cerebellum and its development, describing a living growth cone, the two major modes of axon growth and how they differ, what might cause the mode of axon growth to change, how axonal growth can be subdivided into three stages rather than two, how both losing and gaining axonal connections in development can be correct, and developmental pruning of axons as it occurs naturally.

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    This document contains 9 study questions for a class on central nervous system development. The questions cover topics like the two types of neuronal migration in development, the "inside-out pattern" of neocortex migration, the external granular layer of the cerebellum and its development, describing a living growth cone, the two major modes of axon growth and how they differ, what might cause the mode of axon growth to change, how axonal growth can be subdivided into three stages rather than two, how both losing and gaining axonal connections in development can be correct, and developmental pruning of axons as it occurs naturally.

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    10 views1 page

    9.01 Study Questions: Class 16 (CNS Development, Continued)

    Uploaded by

    djoseph_1
    This document contains 9 study questions for a class on central nervous system development. The questions cover topics like the two types of neuronal migration in development, the "inside-out pattern" of neocortex migration, the external granular layer of the cerebellum and its development, describing a living growth cone, the two major modes of axon growth and how they differ, what might cause the mode of axon growth to change, how axonal growth can be subdivided into three stages rather than two, how both losing and gaining axonal connections in development can be correct, and developmental pruning of axons as it occurs naturally.

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    9.

    01 - Neuroscience & Behavior Fall 2003 Massachusetts Institute of Technology Instructor: Professor Gerald Schneider

    9.01 Study Questions


    Class 16 (CNS Development, continued) 1. Contrast two types of neuronal migration. 2. What is meant by the inside-out pattern of migration in developing neocortex? 3. What is the external granular layer of the cerebellum? What happens to it in the course of mammalian development? 4. Describe a living growth cone as seen in tissue culture. The growth cone was named by ________________________. 5. What are the two major modes of axon growth? How are they different in structural appearance? How else do they differ? 6. What do you think might cause the mode of axon growth to change? 7. Some developmental neurobiologists have described axon growth as occurring in three stages. How would you subdivide the sequence of axonal growth to get three stages rather than just two? (Study the figure.) 8. One student argues that growing axons lose many connections during development. Another insists that connections show large increases in development. How are both of them correct? 9. Describe developmental pruning of axons, as it occurs naturally (without any damage being inflicted).

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