Formulas - Part I (MCQ)

The following formulas are provided for your reference. They do not need to be
memorized as they will be provided in the Examination Booklet.




C
A
=
V
0
0
d
k
0.693
=
t 2 / 1




k
0.105
=
t90
) 1 (
kV
R
= C
d
0 kt
e

AUC
FD
or
AUC
absorbed Amount
=
Cl
0 0
t


kV
R
=
C
d
0
ss




BMI = Body weight (kg) / height
2
(m
2
)


HALF-LIFE
t1/2 = half-life
k = rate constant
SINGLE DOSE IV BOLUS
Vd = Volume of distribution
A0 = Initial dose
C0 = Initial plasma concentration
SHELF-LIFE OF A MEDICATION
t90 = time reach 90% potency
k = rate constant
IV INFUSION DOSING
C = plasma concentration at time t
R0 = infusion rate
k = rate constant
Vd = volume of distribution
CLEARANCE/AUC OF A DOSE
Cl = Clearance
F = Bioavailability
D = Dose given
AUC = Area Under the Curve
IV INFUSION STEADY-STATE
Css = Steady state
R0 = Rate of infusion
k = Rate constant
Vd = Volume of distribution