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What is the pathogenesis of neck lump?

The body tissue exposed


to trauma and trigger the
immune response
Mast cells and basophil
cells will undergo
granulation .
Secretion of inflammatory
mediators such as
histamine, serotonin,
bradykinin, sitokinin in
the form of I!", I!#,
causes dilation of
arterioles
Increasing of
permeability of $enules
as well as the dilatation
of
intraendothelial%unction
The fluid escape from
the blood $essels into
surrounding tissues,
causing bumps on the
area that exposed to the
trauma.
Trauma
In$asion of bacteria
Macrophages,
neutrophils and T cells
trying to destroy the
infectious agent
The infectious agent
itself attempt to
destroy the cells of the
body, in order to
obtain the nutrients
The lymph nodesha$e
to work more than
usual to produce the
lymphoid cell and filter
the damaged tissue
cell
&nlargement of lymph
nodes
Infection
Metaplasia and
dysplasia occurs in
mature cells
'ell differentiation will
not perform perfectly
(bnormalities in cell
di$ision and
inacti$ation of
programmed cell
suicide mechanism
)ncontrolled cell
proliferation
*ormation of bump
+eoplasma

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