Jupiter in the eight house and lagna is Mesh.

Whether
Jupiter is responsible for joint pain? What will be remedial
part? PART-II

Bhava 8 is a very important house, as it
provides openings (both physical and
psychic) which include:
a) Dramatic moments during the wheel of
birth and death.
b) An opening onto mysteries of the "secret"
or things unseen but awareness of their
presence is there.