FC Path(SA) Anat Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain
Reg No 1955/000003/08

Part I Examination for the Fellowship of the
College of Pathologists of South Africa - Anatomical

27 March 2012

1 Paper only (3 hours)

All questions are to be answered. Each question to be answered in a separate book (or books if more than one
is required for the answer)

1 a) Discuss the aetiopathogenesis and pathology of infective endocarditis. (12)
b) Discuss the pathogenesis of Burkitt lymphoma. (8)
c) Write short notes on genomic imprinting. (5)
[25]

2 Discuss
a) The pathogenesis of type I hypersensitivity. (13)
b) Papillary carcinoma of the thyroid gland under the following headings
i) Histopathological features, including of variant forms. (7)
ii) Molecular pathogenesis. (5)
[25]

3 a) Discuss the differential diagnosis of the various types of
granulomatous inflammation seen in the appendix. (13)
b) Describe the macroscopic and microscopic appearance of
i) Pulmonary lymphangitis carcinomatosa. (5)
ii) Pulmonary silicosis. (7)
[25]

4 a) Discuss the pathophysiology of septic shock. (13)
b) Write short notes on
i) Transcription factors. (6)
ii) Cancer cachexia. (6)
[25]