Artifen TM Advanced Nutritional Arthritis Formula Is obtained from the Rhizomes of Curcumin Longa by the solvent extraction method. Curcumin contains unique set of sesquiterpenoids called turmerones. Molecular weight : 368.38 Chemical Formula : C21H20O6 Biological action of Curcumin Benifits: The anti-inflammatory actions of turmeric oil and turmerones have been the subject matter of many scientific investigations including biochemical and animal studies. Multiple mechanisms of actions have been proposed which include inhibition of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and platelet aggregation. Turmerones are also reported to have antioxidant activity. Curcumin acts Anti-Inflammatory agent that relieves aches and pains associated with Arthritis. Curcuma Longa Linn. is official in Indian Pharmacopoeia, United State of Pharmacopoeia, British Pharmacopoeia and European Pharmacopoeia, Australian Register of Therapeutic Goods (ARTG), Indian Herba Pharmacopoeia, German Commission E Monographs, Martindale - The extra Pharmacopoeia, Herbs of Commerce - American Herbal Products Association (AHPA), US FDAs GRAS list. H CO OCH 3 3 HO O O OH Boswellia Serrata Extract Glucosamine MSM Boswellia Serrata Extract is concentrated from specially processed resins & gums of the Boswellia Serrata tree. The benefits of Boswellia are deep to the presence of triterepenic acid. - B-Boswellic Acid - Acetyl B-Boswellic Acid - 11 - Keto - B - Boswellic Acid - Acetyl-11-Keto-B-Boswellic Acid Molecular weight 456.7 Molecular formula C30H48O3 Uses: Boswellic Acid are responsible for Anti-Inflammatory activity in Rheumatoid Arthritis, Low Back Pain and Osteoarthritis. Boswellic Acid are known to reduce joint swelling, maintain blood supply to inflamed joints, and reduces mobility by reducing pain and stiffness in the joints. It also improves immunity in general. 3 30 40 3 3 3 3 3 HOOC C H O HO CH H C CH CH CH H Stimulating the biosynthesis of glycosaminoglycans like Chondroitin Sulphate. Enhances the synthesis of hyaluronic acid, the back bone for proteoglycan Donates the sulphur needed for the formation of compounds like glucosamine & chondroitin sulphate Aids in synthesis of aminoacids - methionine & cysteine