Group Drug

Volume (ml)
before treatment
Volume (ml) after treatment
30 minutes 60 minutes
I
Control 66 6 11
HCT 33 3 11
Furosemide 90 5 21
II
Control 45 5 8
HCT 45 5 8
Spironolactone 60 5 22
III
Control 22 5 20
Furosemide 11 5 5
Spironolactone 8 7 21
IV
HCT 5 6 13
Furosemide 35 11 26
Spironolactone 28 5 13


















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30 minutes 60 minutes 90 minutes 120 minutes
Control Mean
HCT Mean
Furosemide Mean
Spironolactone Mean
Rabbit Drug
Volume (ml)
before treatment
Volume (ml) after treatment
30 minutes 60 minutes
I
Weight:
-
(Just water)
66 ml 6 ml 11 ml
II
Weight: 2,5 kg
HCT

Rabbit dosage:
1

5,825 mg
33 ml 3 ml 11 ml
III
Weight: 3 kg
Furosemide
Rabbit dosage:
2

11,1 mg
90 ml 5 ml 21 ml
1
HCT: 50 mg (human)
Rabbit: 0,07 x 50 mg = 3,5 mg/1,5 kg
Rabbit dosage: 2,33 mg/kg
Rabbit dosage in experiment: rabbit dose/kg x weight = 2,33 mg/kg x 2,5 kg = 5,825 mg
2
Furosemide: 80 mg (human)
Rabbit: 0,07 x 80 mg = 5,6 mg/1,5 kg
Rabbit dosage: 3,7 mg/kg
Rabbit dosage in experiment: rabbit dose/kg x weight = 3,7 mg/kg x 3 kg = 11,1 mg

Time: 13.55
Time: 13.46
Time: 13.49
Time: 14.25
Time: 14.16
Time: 14.19
Time: 14.55
Time: 14.46
Time: 14.49
0
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25
30 minutes 60 minutes 90 minutes 120 minutes
Rabbit 1 (Control)
Rabbit 2 (HCT)
Rabbit 3 (Furosemide)