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92 PDF
Dr Emmeline Heffernan
Research Support:
JDRF Canadian Clinical Trial Network (CCTN)
Postdoctoral Fellowship in Clinical Translation in T1D
Background
CGM provides 288 glucose levels per day,
updated every 5 minutes,
displayed in real time.
But ACTING on information is required
CGM data interpretation can be difficult3
CGM use decreases over time & A1C rises1,4
Pediatric studies: demonstrate need to use CGM at least
6/7 days for improvement in A1C1,2
1JDRF
5Wong
CGM
Arrows
Interpretation of Arrows
CGM
Trend
Arrows
CGM Trend
Arrows
Add 1 units
(3.0ISF=3.0 3 = 1)
Subtract 1 units
(3.0ISF=3.0 3 = 1)
40g CHO
Total Bolus = 5.28 units
BG 8 mmol/L
(144mg/dl)
0.88 units for 2 arrows up
CGM shows
80 g CHO
Bolus wizard: 10.4 units
BG 18 mmol/L Add 20% for
(324mg/dl)
2.08 units for 2 arrows up
CGM shows
Total Bolus = 12.48 units
Population characteristics
Age (yrs)
Gender
Race
Simultaneous
CGM
20
20
40
Mean
12.4
12.03
12.07
SD
3.41
3.26
3.29
Male
13 (65%)
10 (50%)
23 (57.5%)
Female
7 (35%)
10 (50%)
17 (42.5%)
White
19 (95%)
15 (75%)
34 (85%)
Other
1 (5%)
5 (25%)
6 (15%)
4.5
3.9
4.2
Mean
7.94%
8.1%
7.87%
SD
1.06%
0.92%
0.98%
Diabetes
duration (yrs)
HbA1c
CGM start
Number
of uses
per
week
0.93
0.8
0.6
1.02
0.73
0.4
0.2
0
6 weeks
CGM start
3 months
6 months
Conclusion
TAAT uptake was high (87.5%) & sustained over 6
months following CGM initiation (73%)
Frequency of use was variable; subjects used TAAT to
avoid low & high sugars; most frequently used in
evenings
Acknowledgements
I would like to thank JDRF and the Canadian Clinical
Trials Network
I am particularly grateful to JDRF-UK and the Gillespie
Family for their special support, in honour of Ruth
Gillespie.