LSM1401
review think and test questions based on the lecture notes.
Tutorial 4
1. List three ways in which sugars are covalently bonded to each other.
Cellulose 1-4 glycosidic
Nucleotide phospodiester bonds
Agarose 1-3 , 1-4 glycosidic linkage
2. What is the difference between ionic and polar interactions?
Exam question may ask to identify the type
3. What is the difference between 3° and 4° structure of protein globular and fibrous proteins?
4. Van der Waals interactions are responsible for the hydrophobic effect, explain how HE plays a role in nucleic acid duplex formation?
- Base stacking and twisting into a helix
5. Write a 20 nucleotide DNA sequence that will fold into a stem-loop structure with the stem 8 base-pairs long.
6. Most stable duplex?
- Perfect complement
- Least mismatch
- GC ratio
- Location @termini will be more stable than at the centre of the duplex.
LSM1401
review think and test questions based on the lecture notes.
Tutorial 4
1. List three ways in which sugars are covalently bonded to each other.
Cellulose 1-4 glycosidic
Nucleotide phospodiester bonds
Agarose 1-3 , 1-4 glycosidic linkage
2. What is the difference between ionic and polar interactions?
Exam question may ask to identify the type
3. What is the difference between 3° and 4° structure of protein globular and fibrous proteins?
4. Van der Waals interactions are responsible for the hydrophobic effect, explain how HE plays a role in nucleic acid duplex formation?
- Base stacking and twisting into a helix
5. Write a 20 nucleotide DNA sequence that will fold into a stem-loop structure with the stem 8 base-pairs long.
6. Most stable duplex?
- Perfect complement
- Least mismatch
- GC ratio
- Location @termini will be more stable than at the centre of the duplex.
LSM1401
review think and test questions based on the lecture notes.
Tutorial 4
1. List three ways in which sugars are covalently bonded to each other.
Cellulose 1-4 glycosidic
Nucleotide phospodiester bonds
Agarose 1-3 , 1-4 glycosidic linkage
2. What is the difference between ionic and polar interactions?
Exam question may ask to identify the type
3. What is the difference between 3° and 4° structure of protein globular and fibrous proteins?
4. Van der Waals interactions are responsible for the hydrophobic effect, explain how HE plays a role in nucleic acid duplex formation?
- Base stacking and twisting into a helix
5. Write a 20 nucleotide DNA sequence that will fold into a stem-loop structure with the stem 8 base-pairs long.
6. Most stable duplex?
- Perfect complement
- Least mismatch
- GC ratio
- Location @termini will be more stable than at the centre of the duplex.