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  • Abstract Arse P 2008

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    Toon Man
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    An automatic method for change detection between scalar images diffusionweighted, with application to the followup of Multiple Sclerosis lesion evolution. The method relies on the generalized likelihood ratio test, while accounting for the nonstationarity of noise that corrupts these images. Validation has been conducted by simulating lesion appearances in real data.

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    Abstract Arse p 2008

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    An automatic method for change detection between scalar images diffusionweighted, with application to the followup of Multiple Sclerosis lesion evolution. The method relies on the generalized likelihood ratio test, while accounting for the nonstationarity of noise that corrupts these images. Validation has been conducted by simulating lesion appearances in real data.

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    7 views1 page

    Abstract Arse P 2008

    Uploaded by

    Toon Man
    An automatic method for change detection between scalar images diffusionweighted, with application to the followup of Multiple Sclerosis lesion evolution. The method relies on the generalized likelihood ratio test, while accounting for the nonstationarity of noise that corrupts these images. Validation has been conducted by simulating lesion appearances in real data.

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    ANAUTOMATICCHANGEDETECTIONMETHOD

    INDIFFUSIONWEIGHTEDIMAGES:
    APPLICATIONTOMULTIPLESCLEROSIS.
    BOISGONTIERHerva,b,NOBLETVincenta,HEITZFabricea,
    RUMBACHLucienb,c,CATTINFranoisedandARMSPACHJeanPaulb

    LaboratoiredesSciencesdel'Image,del'InformatiqueetdelaTldtection,LSIIT,
    UMRCNRSULP7005,BdSbastienBrant,BP10413,F67412IllkirchCedex,France.
    b
    Laboratoired'ImageriedeNeurosciencesCognitives,LINCIPB,Facultdemdecine,
    UMRCNRSULP7191,4RueKirschleger,F67085StrasbourgCedex,France
    c
    ServicedeNeurologie,dServicedeRadiologie,CHUMinjoz,F25030BesanonCedex,France
    boisgontier@lsiit.ustrasbg.fr
    a

    Abstract
    Magnetic Resonance Imaging (MRI) plays an important role in Multiple Sclerosis (MS) diagnosis and for
    monitoringtheevolutionofthediseaseovertime[1].TheadventofnewquantitativeMRItechniquesandthe
    constantimprovementinspatialresolutionyieldanincreasingamountof3Dimagedata,whoseinterpretationisa
    tediousanderrorpronetask.TheautomaticanalysisofsubtlechangesbetweenMRIscansisanimportanttoolfor
    assessing disease evolution over time. Methods have already been proposed to detect changes in serial
    conventionalMRI[2].However,fewworksaddresschangedetectionindiffusionweightedimaging,whichisa
    promisingtechniqueformonitoringneurodegenerativediseases.Weproposeanautomaticmethodforchange
    detectionbetweenscalarimagesdiffusionweighted,withapplicationtothefollowupofmultiplesclerosislesion
    evolution.Themethodreliesonthegeneralizedlikelihoodratiotest[3],whileaccountingforthenonstationarity
    ofnoisethatcorruptstheseimages.Validationhasbeenconductedbysimulatinglesionappearancesinrealdata.
    Theresultsshowthataccountingforthenonstationarityofnoiseallowstosignificantlyreducethenumberoffalse
    detections.Furtherworkwillalsoconsiderchangedetectiondirectlyontensorimages. Suchautomaticmethods
    forchangedetectionindiffusionweightedimagingmayprovideanobjectivewayforcharacterizingtheevolution
    ofMSlesions,inparticularforthoselocatedinthenormalappearingwhitematter,andausefultoolforstudying
    MSconsequencesonanatomicalandfunctionalbrainconnectivity.

    References
    [1]Y.Ge,Multiplesclerosis:TheroleofMRimaging,AmericanJournalofNeuroradiology,vol.27,no.6,pp.
    11651176,JuneJuly2006.
    [2]M.Bosc,F.Heitz,J.P.Armspach,I.Namer,D.Gounot,andL.Rumbach.Automaticchangedetectionin
    multimodalserialMRI:applicationtomultiplesclerosislesionevolution.NeuroImage,20(2):643656,July2003.
    [3]S.M.Kay,Fundamentalsofstatisticalsignalprocessing:detectiontheory,PrenticeHall,Inc.,UpperSaddle
    River,NJ,USA,1998.

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