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Platelets

Platelets is called thrombocytes smallest cell in blood


The primary function is to aid in the blood clotting process
It is produced from the bone marrow, the large bone marrow is called
MEGAKARYOCTES
Megakaryoctes are huge cell that break into fragment to form platelets
These cell fragment have no nucleus but due contain structures called
granules
Megakaryoctes can produced anywhere from 1000 to 3000 platelets. Platelets
can circulated in blood stream about 9 to 10 days
They become old or damaged, they removed from circulation by the spleen.
Normal platelets range 150000 to 450000 platelets per micro liter of blood
If more 450 000 more - thrombocytosis
If less than 150 000 thrombocytopenia

Blood clotting
Excessive loss in blood is prevented from the cut blood vessels by the formation of
clots. This process is called coagulation

Damaged platelets secrete thromboplastin or throbokinase


Thromokinase is an enzyme that change prothrombine ( present in blood) in
the presence of calcium ion
Fibrin form thread like structure that form a sticky substances at the
damaged portion of the blood vessel
This the network does not allowed to pass through and this plasma which
lacks the fibrinogen is called serum
The mass that is formed at the cut become denser and it is called clot
Normal coagulation required vitamin k and it is followed by clot reaction
( tightening of the solution of the clot) and untimely fibrinolysis ( dissolution
of the blood)
A clotting in an unbroken blood vessel is called thrombosis. Thrombi that
move from the site of the origin is called embolus.

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