Platelets, also called thrombocytes, are cell fragments produced by the bone marrow that aid in blood clotting. Megakaryocytes in the bone marrow break apart to release between 1,000-3,000 platelets each. Platelets circulate in the bloodstream for around 9-10 days, after which they are removed by the spleen if old or damaged. A normal platelet count is 150,000-450,000 per microliter, with lower counts considered thrombocytopenic and higher counts thrombocytotic. When blood vessels are damaged, platelets secrete enzymes and thromboplastin that trigger coagulation and formation of a fibrin mesh to form clots and prevent excessive blood loss.
Platelets, also called thrombocytes, are cell fragments produced by the bone marrow that aid in blood clotting. Megakaryocytes in the bone marrow break apart to release between 1,000-3,000 platelets each. Platelets circulate in the bloodstream for around 9-10 days, after which they are removed by the spleen if old or damaged. A normal platelet count is 150,000-450,000 per microliter, with lower counts considered thrombocytopenic and higher counts thrombocytotic. When blood vessels are damaged, platelets secrete enzymes and thromboplastin that trigger coagulation and formation of a fibrin mesh to form clots and prevent excessive blood loss.
Platelets, also called thrombocytes, are cell fragments produced by the bone marrow that aid in blood clotting. Megakaryocytes in the bone marrow break apart to release between 1,000-3,000 platelets each. Platelets circulate in the bloodstream for around 9-10 days, after which they are removed by the spleen if old or damaged. A normal platelet count is 150,000-450,000 per microliter, with lower counts considered thrombocytopenic and higher counts thrombocytotic. When blood vessels are damaged, platelets secrete enzymes and thromboplastin that trigger coagulation and formation of a fibrin mesh to form clots and prevent excessive blood loss.
Platelets is called thrombocytes smallest cell in blood
The primary function is to aid in the blood clotting process It is produced from the bone marrow, the large bone marrow is called MEGAKARYOCTES Megakaryoctes are huge cell that break into fragment to form platelets These cell fragment have no nucleus but due contain structures called granules Megakaryoctes can produced anywhere from 1000 to 3000 platelets. Platelets can circulated in blood stream about 9 to 10 days They become old or damaged, they removed from circulation by the spleen. Normal platelets range 150000 to 450000 platelets per micro liter of blood If more 450 000 more - thrombocytosis If less than 150 000 thrombocytopenia
Blood clotting Excessive loss in blood is prevented from the cut blood vessels by the formation of clots. This process is called coagulation
Damaged platelets secrete thromboplastin or throbokinase
Thromokinase is an enzyme that change prothrombine ( present in blood) in the presence of calcium ion Fibrin form thread like structure that form a sticky substances at the damaged portion of the blood vessel This the network does not allowed to pass through and this plasma which lacks the fibrinogen is called serum The mass that is formed at the cut become denser and it is called clot Normal coagulation required vitamin k and it is followed by clot reaction ( tightening of the solution of the clot) and untimely fibrinolysis ( dissolution of the blood) A clotting in an unbroken blood vessel is called thrombosis. Thrombi that move from the site of the origin is called embolus.