H3PO4

NaOH NaH2PO4
0.025 n

0.025 n

NaH2PO4

NaOH Na2HPO4

7.0

=
=

pKa
7.21
log

antilog (-0.21)

0.6166

ratio of salt and acid

0.6166 n/ L
1.0000n /L

Theoretical number of moles

+

0.6166 n
1.0000 n
1.6166 n

HP O4

H 2 P O 4

+
+

H 2 P O4

2
(HP O4 )

H2O pKa 7.21

0.010 n

7.0 7.21

H 2 P O4

2
(HP O4 )

H2O pKa 2.12

0.015 n

0.010 n

pH

log
log

(salt )
(acid)

H 2 P O4

2
(HP O4 )

Actual number of moles of phosphate buffer

250 mL

1L
=0.250 L
1000 mL

0.1n
0.250 L=0.025 n
L

Actual number of moles of

HP O4

0.6166 n n HP O4
=
1.6166 n
0.025 n

HP O4

= 0.010 n

Actual number of moles of

H 2 P O4

O4
n H2 P
0.025 n
1.0000 n
=
1.6166 n

H 2 P O 4

= 0.015 n

Amount needed if materials available are 15 M H3PO4 and

6 M NaOH
mL of H3PO4 needed
0.025 n

1 L 1000 mL

=1.67 mL H 3 P O4
15 n
1L

mL of 6 M NaOH
0.025 n + 0.010 n = 0.035 n
0.0 3 5 n

1 L 1000 mL

=5.83 mL NaOH
6n
1L