Professional Documents
Culture Documents
27-62
1
(fecal impaction)
(diverticular disease) (volvulus)2
(autonomic hyperreflexia (AH) or
dysreflexia)1 reflex vasoconstriction
(level of spinal cord injury)
(tachycardia or bradycardia)
(diaphoresis)
( T6 )
Lynch3
467 3
79
1) (fecal incontinence
score)
complete cord lesion incomplete cord lesion
2)
62 8
3)
15 61
9
20-584,5
(complete lesion)3
(C-level injury)
(multisystem trauma)
(motor neurons)
1. Supranuclear (supraconal) lesion
conus medullaris/sacral level (S2-S4)
80
, - 2557
(upper
motor neuron; UMN)
T5
(intercostal muscle)
6
(hyperreflexic bowel) (tone)
7 (external
anal sphincter; EAS)
(UMN)
2. Infranuclear lesion
conus medullaris (S2-S4)
(lower motor neuron; LMN)
(areflexic bowel)
(tone) (rectum)
(rectal compliance)
(tone)
parasympathetic
(resting anal tone)
valsava maneuver
reflex-mediated defecation
81
1. (effects on
colorectal motility and transport)
1.1 (colonic transit
time)
Krogh8
supraconal conal/quada equina lesions
gastrointestinal Transit Time (GITT)
(ascending, transverse, descending and rectosigmoid colon) (colonic transit time; CTT) conal
quada equina transit time rectosigmoid colon
1
() GITT
CTT
conal/quada equina transit time
, - 2557
83
2. (defecation)
(anorectal manometry)11
37 rectal compliance
incomplete injury rectal sensation complete
injury
3 (non-pharmacological) (pharmacological)
(surgery)
1. (non-pharmacological)
1.1
transit time
12,13
1.2 (digital rectal stimulation)
5 1 2
14
1.3 (abdominal massage)
gastrointestinal transit time
(cecum)
15 15
1.4 (irrigation technique)
peristeen anal irrigation rectal cath84
, - 2557
eter
16,17
1.5 Functional electrical and magnetic stimulation of skeletal muscles
(complete injury)
T10 electrode
external oblique rectus abdominis
25-40 Hz 6 6 25
colonic transit time ascending, transverse descending
colon rectosigmoid colon18
2. (pharmacological)
prokinetic drugs
cisapride, prucalopride neostigmine
(suppositories)
2.1 Prokinetic drugs
Cisapride
randomized, controlled trial (RCT)19-21 cisapride
colonic transit time
Prucalopride highly selective serotonin receptor agonist RCTl22 stool frequency
stool consistency gastrointestinal transit time
1 mg
85
2 mg
( 50
)
Neostigmine RCT23 3
(normal saline) neostigmine
neostigmine glycoporrate (selective anticholinergic
agent)
(mean time to evacuation) (placebo) glycoporrate
2.2 (suppositories)
glycerine
bisacodyl
HVB (hydrogenated vegetable oil-based bisacodyl)
PEG (polyethylene glycol-based bisacodyl)
PEG base 24,25
3. (surgery)
70
3
3.1 (implantation of electrical stimulant
systems)
(sacral anterior root stimulation)
86
, - 2557
S2, S3 S4
0.5 3 15
(bladder muscle)
(urethral sphincter) (anal sphincter) motor
nerve motor, sensory autonomic system26
27,28
3.2 (colostomy)
29,30
1 The Malone Antegrade Continence Enema and the Enema Continence (MACE)
87
3.3 The Malone Antegrade Continence Enema and the Enema Continence (MACE)
appendiostomy (
1) catheter
31
1. Ebert E. Gastrointestinal Involvement in Spinal Cord Injury: a Clinical perspective. J Gastrointestin Liver Dis. 2012;21:75-82.
2. Lynch AC, Frizelle FA. Colorectal motility and defecation after spinal cord injury
in humans. Prog Brain Res. 2006;152:335-43.
3. Lynch AC, Wong C, Anthony A, Dobbs BR, Frizelle FA. Bowel dysfunction
following spinal cord injury: a description of bowel function in a spinal cordinjured population and comparison with age and gender matched controls.
Spinal Cord. 2000;38:717-23.
4. Ng C, Prott G, Rutkowski S, Li Y, Hansen R, Kellow J, et al. Gastrointestinal
symptoms in spinal cord injury: relationships with level of injury and psychologic factors. Dis Colon Rectum. 2005;48:1562-8.
5. DeLooze D, Van Laere M, De Muynck M, Beke R, Elewaut A. Constipation and
other chronic gastrointestinal problems in spinal cord injury patients. Spinal
Cord. 1998;36:63-6.
6. MacDonagh R, Sun WM, Thomas DG, Smallwood R, Read NW. Anorectal function in patients with complete supraconal spinal cord lesions. Gut. 1992;33:15328.
7. Krogh K, Mosdal C, Gregersen H, Laurberg S. Rectal wall properties in patients
with acute and chronic spinal cord lesions. Dis Colon Rectum. 2002;45:641-9.
88
, - 2557
89
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
90
29. Rosito O, Nino-Murcia M, Wolfe VA, Kiratli BJ, Perkash I. The effects of colostomy on the quality of life in patients with spinal cord injury: a retrospective
analysis. J Spinal Cord Med. 2002;25:174-83.
30. Munck J, Simoens Ch, Thill V, Smets D, Debergh N, Fievet F, et al. Intestinal
stoma in patients with spinal cord injury: a restrospective study of 23 patients.
Hepatogastroenterology. 2008;55:2125-9.
31. Christensen P, Kvitzau B, Krogh K, Buntzen S, Laurberg S. Neurologic colorectal
dysfunction use of new antegrade and retrograde wash-out method. Spinal
Cord. 2000;38:255-61.
91