Professional Documents
Culture Documents
Pharmacokinetics:
Absorption: Rapidly absorbed (75%) from the GI tract. Food decreases
absorption.Distribution: Widely distributed but does not cross the blood brain
barrier. Crosses the placenta, small amounts enter breast milk.Metabolism and
Excretion: 50% metabolized by the liver. 50% excreted unchanged by the
kidneys.
Pharmacodynamics:
Instruct patient to take captopril exactly as directed. Missed dose should be taken
as soon as remembered but not if almost time for next dose.
Do not double doses.
Instruct patient not to discontinue captopril therapy unless directed by health care
provider.
Encourage patient to comply with additional interventions for hypertension.
Instruct patient and family on proper technique of blood pressure monitoring.
Advice them to check blood pressure at least weekly and to report any significant
changes.
Caution patient to avoid foods containing high levels of sodium or potassium.
Advice patient that any changes in taste sensation will reverse itself within 8-12
weeks.
Instruct patient to change position slowly to minimize occurrence of orthostatic
hypotension.
Advice patient that exercising in hot weather may increase hypotensive effect.
Instruct patient to consult with a health care provider before taking any over the
counter medications or cold remedies.
Advice patient of ingesting excessive amount of tea, coffee or cola.
Advice patient to avoid driving or other activities that require alertness until
response to therapy is known.
Instruct patient to notify health care provider if rash, sore throat, fever, irregular
heart beat, chest pain, swelling of face, eyes, lips or tongue and difficulty of
breathing occurs.
Emphasize importance of follow up examinations for monitoring purposes.
Nursing Diagnosis: