Professional Documents
Culture Documents
study
By
Angela Long, RN and Myriam Diatta, RN
What is Syphilis?
Highly contagious sexually transmitted
disease that first appeared in Europe in late
15th century
Transmitted by the bacterium Treponema
Pallidum
Syphilis infection has 3 stages (primary,
secondary and late stage)
Treatment of Syphilis
In 1947, Penicillin became the main treatment for
syphilis
A single dose of Penicillin G is given intramuscular to
treat the infection if infected for less than a year.
If infected for more than a year or for an unknown
period of time, Penicillin is given weekly for 3 weeks
Doxycycline or Tetracycline is administered to those
allergic to Penicillin
If left untreated, syphilis can cause permanent
health problems such as blindness, dementia or even
death.
Unethical Principles
Conclusion
The Tuskegee experiment was known for one
of the most non-therapeutic study in the
United States
Resulted in a decrease in trust of researchers
from African Americans
Caused hundreds of death, infected wives
and children born with congenital syphilis.
References
Beauchamp, T., & Childress, J. (2013). Principles of Biomedical Ethics (7th ed.). New York:
Oxford University Press.
Center for disease control and Prevention (2013) U.S. Public Health Service Study at
Tuskegee. Retrieved from http://www.cdc.gov/tuskegee/timeline.htm
Karamanou, M., Kyriakis, K., Tsoucalas, G., & Androutsos, G. (2013). Hallmarks in history of
syphilis therapeutics. Le Infezioni in Medicina, 4(1), 317-319. Retrieved from
www.pubmed.com
Mays, V. M. (2012, November 1). The legacy of the us public health service study of untreated
syphilis in african american men at Tuskegee on affordable care act and health care reform
years after president Clintons apology. Ethics Behavior, 22(6), 411-418.
http://dx.doi.org/10.1080/10508422.2012.730808
Protection of human subjects and informed consent. (2014). Retrieved from
http://www.fda.gov/science research
Rancher, W., & Wolf, L. (2013, December). Redressing past wrongs: changing the common
rule to increase minority voices in research. American Journal of Public Health, 2136-2140.
http://dx.doi.org/10.2105%fajph.2013.301356
Syphilis CDC fact sheet. (2014). Retrieved from http://www.cdc.gov/std
Tampa, M., Sarbu, I., Matei, C., Benea, V., & Georgescu, S. (2014, March 15). Brief history of
syphilis. Journal of Medicine and Life, 7(1), 4-10. Retrieved from www.ncbi.nlm.nih.gov
The Tuskegge timeline. (2014). Retrieved from www.cdc.gov/tuskegee/timeline.htm
Varmus, H., & Snatcher, D. (2014, October 2). Ethical complexities of conducting research in
developing countries. The New England Journal of Medicine, 337-348.
http://dx.doi.org/10.1056/NELM201410023371411