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Lecture 4
Muscle and Nerve Tissue
2015
Objectives
Describe general features of muscle tissue
Understand location, structure, function
Muscle Tissue
There are three types of muscle
comprising ~50% of the body tissue
mass:
i. Skeletal Muscle
ii. Cardiac Muscle
iii.Smooth Muscle
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i.
Skeletal Muscle
There are about 650 named skeletal muscles in
the body
Stapedius
knee: flexor).
Sartorius
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www.dbtechno.com
Control
Voluntary
ii Cardiac Muscle
Striated. Branched.
Single central nucleus.
Fibres join end-to-end through intercalated discs.
Desmosome
Gap junction
GJ
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Type
Cardiac
Location
Heart
Structure
Striated; branched;
single central nucleus;
intercalated discs
Control
Involuntary
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Location
In the walls of hollow
internal structures
e.g. blood vessels,
intestines, skin
Control
Involuntary
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Nervous Tissue
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4. Nervous Tissue
Nervous tissue is the essential component of the nervous system.
The nervous system has two main subdivisions:
Central nervous system (CNS): brain and spinal cord
Peripheral nervous system (PNS): all nervous tissue outside CNS
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Neurons
Have a cell body into which short, branched dendrites convey nerve
impulses (action potentials) and from which a longer, single axon
conducts nerve impulses to another neuron or tissue.
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Multipolar Neurons
Have 2 or more dendrites
and a single axon.
Most common neurons in
CNS
All motor neurons (control
skeletal muscle) are in
this class
Some of longest (spinal
cord to toe muscles)
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Bipolar Neurons
Two distinct processes
1 dendritic processes (can
branch at tip but not at cell
body)
And 1 axon
Unipolar Neuron
The dendrites and axon
are continuous
Cell body off to one side
Whole thing from where
dendrites converge called
axon
Most sensory nerves are
unipolar
Very long (1m) like motor
nerves CNS-toe tip.
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Anaxonic neuron
Rare and function
poorly understood
Anatomy cannot
distinguish dendrites
from axons
Found in brain and
special sense organs
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Neuroglia
Found in both CNS and PNS.
Make up about half the volume of the CNS (glue).
Smaller than neurons but more numerous (5-50x)
Do not propagate action potentials, but can communicate.
Can divide within the mature nervous system
Functions
Physical structure of nervous tissue
Repair framework of nervous tissue
Undertake phagocytosis
Nutrient supply to Neurons
Regulate interstitial fluid in neural tissue.
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Classification of Neuroglia
1. CNS Neuroglia
i.
Astrocytes:
a. Star-shaped; largest; most
numerous. Syncytium network.
b. Support (have microfilaments)
and repair (scar).
c. Communicate with neurons via
gliotransmitters e.g. glutamate
d. Maintain environment around
neuron by eg regulating ions.
e. Maintain blood-brain barrier via
endothelium. Wrap around vessels
and influence their permeability
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ii. Oligodendrocytes:
Form insulating multilayered
myelin sheath ( protein lipid
layer) around CNS axons. Can
myelinate more than one
neuron cells axon. Accelerate
the action potential.
iii. Microglia:
Phagocytic (resident
macrophages) - protection
Oligodendrocyte
Inactive microglia
http://drgominak.com
Active microglia
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Blausen.com staff
Martin Hasselblatt
Ependymal cells
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ii.
Schwann cells: form insulating myelin sheath around axons or can just
support and surround several non-myelinated axons. (Note: One schwann
cell per axon for myelination but more axons/cell if just support).
Satellite cells: surround neuron cell bodies. Support and fluid exchange
(equiv. to astrocytes in CNS).
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Myelinating Schwann
Non-Myelinating Schwann
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