Basic About Tetramethylammonium Hydroxide

Hydroxide
Hydroxide chemical formula OH. It consists of an oxygen and a hydrogen atom held together by
sharing of electron pairs, and carries a negative electric charge.
Products of hydroxide, which are manufactured at Tatvachintan Pharma Chem Pvt. Ltd. are:

Tetramethylammonium hydroxide

Tetraethyletraethylammonium hydroxide

Tetrapropylammonium hydroxide

Tetrabutylammonium hydroxide

Benzyltrimethylammonium hydroxide

Tetramethylammonium hydroxide:
Tetramethylammonium hydroxide (TMAH) is a quaternary ammonium salt, the molecular formula
is N(CH3)4+OH, and is one of the simplest members of this class of organic compounds. This
substance is known in a (relatively) stable solid form only as the pentahydrate. Commercially, the
forms in which TMAH is most commonly encountered are as concentrated solutions in water or
methanol. The solid and solutions are colorless, or yellowish if impure. Although TMAH has
virtually no odor when pure, samples often have a strongly fishy smell from the trimethylamine
which is commonly present as an impurity.

Prepration:

Tetramethylammonium hydroxide is highly toxic chemical. Methanol is flammable and

toxic.

Avoid skin and eye contact with this material.

Known the location of the fire extinguisher, eyewasher, and safty shower before beginning
work.

Eliminate sources of ignition from the potential spill area.

TMAH is very toxic and should not contact your skin. Recent industrial experience indicates

Tatvachintan Pharma Chem Pvt. Ltd.

Basic About Tetramethylammonium Hydroxide

that skin exposure to TMAH solution as dilute as 25%.

Thus skin exposure to >1% TMAH over a few percent of the body must be treated as a life
threating event.

Storage & disposal:

Stability: Stable under ordinary conditions of use and storage. Readily absorbs CO2 from the air.
Incompatibilities: Strong acids and oxidizing agents, attacks many plastics and rubbers. May react
with metallic aluminum and generate hydrogen gas,. Keep away from organic halogens.
Conditions to Avoid: Heat, flames, ignition, source and incompatibles.
Storage: Container should be tightly closed in a well-ventilated area away from acids, oxidizers and
sources of ignition. Store in secondary containment.
Disposal: Collect all tetramethylammonium hydroxide liquid waste in labeled 1 gal. Plastic
container. Don't mix with incompatibles. Don't mix strongly acidic aqueous waste streams.
Tatva chintan is a globally recognized, integrated pharmaceutical company with core competencies
in the development and manufacture of hydroxide chemicals.

Tatvachintan Pharma Chem Pvt. Ltd.