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LIPID PROFILE

By Micheal and Christian

Whats Lipid Profile?

Quantitative analysis of the lipid


metabolism markers in the blood

It includes levels of total cholesterol, LDL,


HDL,VLDL, Triglycerides and others

Most of the factors included are considered


as risk factors, HDL is a protective factor

How is it performed?

A blood sample is taken through


venipuncture

Blood is usually obtained for the median


cubital vein

It will be analyzed in the lab to determine


the quantities of all factors we are
interested in

Patient should fast 9-12 hrs before

When to get one?

The risk of developing coronary heart


disease is the major cause for ordering a
lipid profile

If the results are normal, it is recommended


every five years starting age 20

However if the patient has diabetes, CVD, or


Hypertension then it is performed more
regularly under a doctors surveillance.

Normal Values

LDL : <130mg/dl (lower is better)

VLDL : 2-30 mg/dl

HDL : >40-60 mg/dl (higher is better)

Total Cholesterol : <200 mg/dl

Triglyceride : 10-150 mg/dl (lower is better)

High Cholesterol, LDL, VLDL,


Triglycerides

Can be inherited, but preventable and


treatable

High correlation with heart disease


according to the Framingham Studies

Very dangerous, especially in patients with


hypertension, CVD, or diabetes

Causes
Obesity
Diabetes
Hypothyrodism
Kidney Disease
Lots of alcohol
Smoking and sedentary lifestyle
Some medications : estrogen, birth control
pills, diuretic

HDL

Good cholesterol

Small new subtype with apo-cIII might


increase CVD risks

Anti-thrombotic, anti-inflammatory , antisclerotic

We should higher our HDL

How to boost HDL

Do not smoke

Exercise

Choose healthy fats

Lose weight

Do not drink alot

HDL friendly foods

Fresh Nuts

Fish in general

Olive oil

Avocado and other healthy fats

Oatmeal and fibers

Our Patient

Cholesterol : 310 mg/dl (high > 200)

LDL 241mg/dl

HDL : 37 mg/dl (normal)

Triglycerides : 150 mg/dl (Upper boundary


at 150)

(high >130)

Our Patient

Therefore one could easily infer that with all


the elevated lipid profile indicators, she is at
high risk of developing CVDs

This risk factor combined with others which


the patient has (smoking, obesity) should
be of the doctors interest

She needs management of her risk factors

References

http://
www.nlm.nih.gov/medlineplus/ency/article/
003491.htm

http://
www.sparkpeople.com/resource/slideshow.
asp?show=50

http://
www.mayoclinic.com/health/hdl-cholesterol
/CL00030

THANK YOU

Micheal and Christian

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