Cellular division

Regenerate damaged tissues

Mitosis
Division of chromosomes into 2 nuclei
Cytokinesis
Division of cytoplasm into 2 cells
Genome
In bacteria, it has only 1 circular dna molecule, still considered a genome
In Eukaryotics, it has chromosomes of linear dna molecule depending on
the species, the make up of dna molecule = genome
Chromosomes
Packaged dna molecules
Clicker 1 question
True
Dna = manual book
Tells the cell how to behave
Ex, the liver cell would open up a chapter on how to be a liver cell, etc.
Cellular organization
Dna is double stranded
Wraps around histones in order to form nucleosomes
Balls wrapped with dna strands
Balls wrapped with dna strands (nucleosomes) wraps around1 itself = coiled
coil chromatin bundle
Clicker 2
B.
Clicker 3
B
Chromosome is just a term for the MOST packaged DNA
DNA has to be accessible for genes to be transcribed and for the cells to
function properly
Importance of chromosomes
Need chromosomes, condensed dna in order to be organized and easier to
maneuver, less messy, strands wont get messy and tangled
Microtubules = roads to move shit in cells
Mitotic phase split into mitosis & cytokinesis
Mitotis
Prophase, prometaphase, metaphase, anaphase, telophase,
Cytokinesis
Overlaps with telophase
Interphase is alternated with the mitotic phase in the cell cycle. What is the
interphase?
Genome = total dna containing an organisms complete set of genes
Chromosome = 1 unit of double stranded dna, 1 set contains the genome
Diploid = 2 sets of chromosomes. Maternal & paternal
Chromosomes condensed in G2 phased, in prep for cell division,
Clicker 4
D, no need to duplicate chromosomes if they arent going to divide

 Neurons Cant do anything with condensed dna material

Plant cells dont have centrioles
Youtube video mitosis
Cell cycle must be tightly regulated
Ensure an organisms function
Cell type & turnover chat in lecture slide
Molecular control system = regulates eukaryotic cell cycle
Experiment in lecture slide
There is something in the cytoplasm that controls the cells phase
Clicker 5
A
Cell signaling
Signaling molecule is a growth factor?

Lecture Part II