Powers appeared in several motion pictures in the early 1960s in secondary roles such as the

thriller Experiment in Terror, If a Man Answers, and McLintock! (1963). She played a schoolgirl
in Tammy Tell Me True (1961) and Bunny, the police chief's daughter, in Palm Springs Weekend (1963).
She appeared in the 1962 hospital melodrama The Interns, and its sequel, The New Interns in 1964. In
1965 she played opposite Tallulah Bankhead in Die! Die! My Darling (originally released in England
as Fanatic).
In 1966 her "tempestuous" good looks led to being cast in the starring role as the passive and demure
April Dancer, in the short-lived NBC television spy thriller series The Girl from U.N.C.L.E., a spinoff of The Man from U.N.C.L.E. Shortly after the series' debut, she was featured on the cover of TV
Guide (December 31, 1966 January 6, 1967). The article mentions her "117-pound frame is kept
supple with 11 minutes of Royal Canadian Air Forceexercises every morning... Unlike her fellow
U.N.C.L.E. agents, the ladylike April is not required to kill the bad guys. Her feminine charms serve as
the bait, while her partner Noel Harrison provides the fireworks". The series lasted for only one season
(29 one-hour episodes), airing from September 16, 1966 to April 11, 1967.