Lampiran 1

SURAT HASIL DETERMINASI ASAM JAWA

29

30

Lampiran 2
Tanaman Asam Jawa

Gambar 1.Pohon asam jawa

Gambar 2.Buah dan Daun asam jawa

31

Gambar 3.Daging buah asam jawa kering

Gambar 4. Simplisia daun dan buah asam jawa

32

Lampiran 3
Ekstrak

Gambar 5. Ekstrak buah asam jawa

Gambar 6. Ekstrak daun asam jawa

33

Lampiran 4
Plestimometer

Gambar 7
Plestimometer

Gambar 8
Penyuntikan telapak kaki tikus karagenan 1%

34

Gambar 9
Pencelupan telapak kaki tikus

35

Lampiran 5
Tabel 1. Hasil uji statistik Karagenan
Kriteria uji :
Jika nilai signifikansi 0,05 maka Ho diterima
Jika nilai signifikansi <0,05 maka Ho ditolak

Karagenan 0,1 mL

Sum of Squares

Df

Mean Square

Between Groups

.000

.000

Within Groups

.002

19

.000

Total

.002

20

Karagenan 0,2 mL

Sum of Squares

df

Mean Square

Between Groups

.004

.004

Within Groups

.003

19

.000

Total

.007

20

Sig.
.443

F
27.045

.514

Sig.
.000

36

Lampiran 6
Tabel 2. HASIL UJI T-STUDENT

Kriteria uji :
Jika nilai signifikansi 0,05 maka Ho diterima
Jika nilai signifikansi <0,05 maka Ho ditolak

Paired Differences
Kontrol
Mean
Pair 1

T0 - T3

-.044167

Std.

Std.

95% Confidence Interval

Deviatio

Error

of the Difference

Mean

.005845

Lower
.

-.050301

df

Sig. (2-tailed)

Upper
-.038032

-18.508

.000

00238
6

Pembanding natrium
diklofenak
0,45mg/kgBB
Pair 1

T0 - T3

Pembanding natrium
diklofenak
0,9mg/kgBB
Pair 1

T0 - T3

Paired Differences
95% Confidence Interval
Std.
of the Difference
Error
Mean
Lower
Upper
t
.005481 -.047423
-.019243 -6.081

Std.
Deviatio
Mean
n
-.033333 .013426

Paired Differences
95% Confidence Interval
Std.
Std.
of the Difference
t
Deviatio Error
Mean
n
Mean
Lower
Upper
-.021667 .009832 .004014 -.031985
-.011349 -5.398

df

df

Sig. (2-tailed)
5
.002

Sig. (2-tailed)
5

.003

37

Paired Differences
Uji Buah asam jawa
Mean
Pair 1

T0 - T3

-.033333

Std.
Deviation

Std.
Error
Mean

.012111 .004944

-.046043

-.020624 -6.742

Paired Differences
Uji Daun asam
jawa
Mean
Pair 1

T0 - T3

-.028333

Std.
Deviation

Std.
Error
Mean

.012111 .004944

Mean
Pair 1 T0 - T3

-.029167

Std.
Deviation

Std.
Error
Mean

.013571 .005540

Sig. (2-tailed)

df

.001

Sig. (2-tailed)

95% Confidence Interval

of the Difference
Lower
Upper
-.041043

-.015624 -5.731

Paired Differences
Uji Kombinasi asam
jawa

df

95% Confidence Interval

of the Difference
Lower
Upper

df

.002

Sig. (2-tailed)

95% Confidence Interval

of the Difference
Lower
Upper
-.043408

-.014925 -5.264

.003

38

Lampiran 7
Tabel 3. Hasil Uji Statistik ANOVA

Kriteria uji :
Jika nilai signifikansi 0,05 maka Ho diterima
Jika nilai signifikansi <0,05 maka Ho ditolak
Sum of Squares
T0

T1

T2

T3

T4

T5

df

Mean Square

Between Groups

.000

.000

Within Groups

.001

35

.000

Total

.001

41

Between Groups

.003

.000

Within Groups

.002

35

.000

Total

.005

41

Between Groups

.006

.001

Within Groups

.002

34

.000

Total

.008

40

Between Groups

.007

.001

Within Groups
Total

.003

35

.000

.010

41

Between Groups

.008

.001

Within Groups
Total

.003

35

.000

.012

41

Between Groups

.009

.001

Within Groups
Total

.005

35

.000

.014

41

.004

.001

.003

35

.000

.007

41

.002

.000

.002

35

.000

.004

41

T24 Between Groups

Within Groups
Total
T30 Between Groups
Within Groups
Total

Sig.

.192

.977

9.266

.000

16.718

.000

12.867

.000

14.530

.000

10.213

.000

8.313

.000

5.806

.000

39

T0

kontrol positif

kontrol negatif

pembanding 25 mg

pembanding 50 mg

uji buah

uji daun

uji kombinasi

(J) Kelompok

Mean
Difference
(I-J)
kontrol negatif
.000000
Pembanding 25 mg
.000000
pembanding 50 mg
.000000
uji buah
-.001667
uji daun
-.001667
uji kombinasi
-.000833
kontrol positif
.000000
pembanding 25 mg
.000000
pembanding 50 mg
.000000
uji buah
-.001667
uji daun
-.001667
uji kombinasi
-.000833
kontrol positif
.000000
kontrol negatif
.000000
pembanding 50 mg
.000000
uji buah
-.001667
uji daun
-.001667
uji kombinasi
-.000833
kontrol positif
.000000
kontrol negatif
.000000
pembanding 25 mg
.000000
uji buah
-.001667
uji daun
-.001667
uji kombinasi
-.000833
kontrol positif
.001667
kontrol negatif
.001667
pembanding 25 mg
.001667
pembanding 50 mg
.001667
uji daun
.000000
uji kombinasi
.000833
kontrol positif
.001667
kontrol negatif
.001667
pembanding 25 mg
.001667
pembanding 50 mg
.001667
uji buah
.000000
uji kombinasi
.000833
kontrol positif
.000833
kontrol negatif
.000833
pembanding 25 mg
.000833
pembanding 50 mg
.000833
uji buah
-.000833
uji daun
-.000833
Lampiran 8

95% Confidence Interval

Std.
Error
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559
.002559

Tabel 4. Hasil Uji Statistik lanjutan L

Sig. Lower Bound

1.000
-.00519
1.000
-.00519
1.000
-.00519
.519
-.00686
.519
-.00686
.747
-.00603
1.000
-.00519
1.000
-.00519
1.000
-.00519
.519
-.00686
.519
-.00686
.747
-.00603
1.000
-.00519
1.000
-.00519
1.000
-.00519
.519
-.00686
.519
-.00686
.747
-.00603
1.000
-.00519
1.000
-.00519
1.000
-.00519
.519
-.00686
.519
-.00686
.747
-.00603
.519
-.00353
.519
-.00353
.519
-.00353
.519
-.00353
1.000
-.00519
.747
-.00436
.519
-.00353
.519
-.00353
.519
-.00353
.519
-.00353
1.000
-.00519
.747
-.00436
.747
-.00436
.747
-.00436
.747
-.00436
.747
-.00436
.747
-.00603
.747
-.00603

Upper Bound
.00519
.00519
.00519
.00353
.00353
.00436
.00519
.00519
.00519
.00353
.00353
.00436
.00519
.00519
.00519
.00353
.00353
.00436
.00519
.00519
.00519
.00353
.00353
.00436
.00686
.00686
.00686
.00686
.00519
.00603
.00686
.00686
.00686
.00686
.00519
.00603
.00603
.00603
.00603
.00603
.00436
.00436

40

T1

kontrol positif

kontrol negatif

pembanding Na 25
mg

pembanding Na 50
mg

uji buah

uji daun

(J) Kelompok

kontrol negatif
pembanding 25 mg
pembanding 50 mg
uji buah
uji daun
uji kombinasi
kontrol positif
pembanding 25 mg
pembanding 50 mg
uji buah
uji daun
uji kombinasi
kontrol positif
kontrol negatif
pembanding 50 mg
uji buah
uji daun
uji kombinasi
kontrol positif
kontrol negatif
pembanding 25 mg
uji buah
uji daun
uji kombinasi
kontrol positif
kontrol negatif
pembanding 25 mg
pembanding 50 mg
uji daun
uji kombinasi
kontrol positif
kontrol negatif
pembanding 25 mg
pembanding 50 mg
uji buah
uji kombinasi

Mean
Difference
(I-J)
Std. Error
*
.028333
.004126
.008333
.004126
*
.015000
.004126
.005833
.004126
.010000*
.004126
*
.010000
.004126
-.028333*
.004126
-.020000*
.004126
-.013333*
.004126
-.022500*
.004126
-.018333*
.004126
-.018333*
.004126
-.008333
.004126
.020000*
.004126
.006667
.004126
-.002500
.004126
.001667
.004126
.001667
.004126
-.015000*
.004126
.013333*
.004126
-.006667
.004126
-.009167*
.004126
-.005000
.004126
-.005000
.004126
-.005833
.004126
.022500*
.004126
.002500
.004126
.009167*
.004126
.004167
.004126
.004167
.004126
-.010000*
.004126
.018333*
.004126
-.001667
.004126
.005000
.004126
-.004167
.004126
.000000
.004126

kontrol positif
-.010000*
kontrol negatif
.018333*
pembanding 25 mg
-.001667
pembanding 50 mg
.005000
uji buah
-.004167
uji daun
.000000
*. The mean difference is significant at the 0.05 level.
uji kombinasi

.004126
.004126
.004126
.004126
.004126
.004126

95% Confidence Interval

Sig. Lower Bound Upper Bound
.000
.01996
.03671
.051
-.00004
.01671
.001
.00662
.02338
.166
-.00254
.01421
.021
.00162
.01838
.021
.00162
.01838
.000
-.03671
-.01996
.000
-.02838
-.01162
.003
-.02171
-.00496
.000
-.03088
-.01412
.000
-.02671
-.00996
.000
-.02671
-.00996
.051
-.01671
.00004
.000
.01162
.02838
.115
-.00171
.01504
.548
-.01088
.00588
.689
-.00671
.01004
.689
-.00671
.01004
.001
-.02338
-.00662
.003
.00496
.02171
.115
-.01504
.00171
.033
-.01754
-.00079
.234
-.01338
.00338
.234
-.01338
.00338
.166
-.01421
.00254
.000
.01412
.03088
.548
-.00588
.01088
.033
.00079
.01754
.319
-.00421
.01254
.319
-.00421
.01254
.021
-.01838
-.00162
.000
.00996
.02671
.689
-.01004
.00671
.234
-.00338
.01338
.319
-.01254
.00421
1.000
-.00838
.00838

.021
.000
.689
.234
.319
1.000

-.01838
.00996
-.01004
-.00338
-.01254
-.00838

-.00162
.02671
.00671
.01338
.00421
.00838

41

T2

(J) kelompok

Mean
Difference (I-J) Std. Error
kontrol positif
kontrol negatif
.040333*
.004620
*
pembanding na 25 mg
.011000
.004620
pembanding na 50 mg
.022000*
.004620
uji daun
.009000
.004620
uji buah
.008667
.004620
uji kombinasi
.013167*
.004620
kontrol negatif kontrol positif
-.040333*
.004620
*
pembanding na 25 mg
-.029333
.004405
pembanding na 50 mg
-.018333*
.004405
uji daun
-.031333*
.004405
uji buah
-.031667*
.004405
uji kombinasi
-.027167*
.004405
pembanding Na kontrol positif
-.011000*
.004620
25 mg
kontrol negatif
.029333*
.004405
pembanding na 50 mg
.011000*
.004405
uji daun
-.002000
.004405
uji buah
-.002333
.004405
uji kombinasi
.002167
.004405
pembanding Na kontrol positif
-.022000*
.004620
50 mg
kontrol negatif
.018333*
.004405
pembanding na 25 mg
-.011000*
.004405
uji daun
-.013000*
.004405
uji buah
-.013333*
.004405
uji kombinasi
-.008833
.004405
uji daun
kontrol positif
-.009000
.004620
kontrol negatif
.031333*
.004405
pembanding na 25 mg
.002000
.004405
pembanding na 50 mg
.013000*
.004405
uji buah
-.000333
.004405
uji kombinasi
.004167
.004405
uji buah
kontrol positif
-.008667
.004620
*
kontrol negatif
.031667
.004405
pembanding na 25 mg
.002333
.004405
pembanding na 50 mg
.013333*
.004405
uji daun
.000333
.004405
uji kombinasi
.004500
.004405
uji kombinasi
kontrol positif
-.013167*
.004620
*
kontrol negatif
.027167
.004405
pembanding na 25 mg
-.002167
.004405
pembanding na 50 mg
.008833
.004405
uji daun
-.004167
.004405
uji buah
-.004500
.004405
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB

Sig.
.000
.023
.000
.060
.069
.007
.000
.000
.000
.000
.000
.000
.023
.000
.018
.653
.600
.626
.000
.000
.018
.006
.005
.053
.060
.000
.653
.006
.940
.351
.069
.000
.600
.005
.940
.314
.007
.000
.626
.053
.351
.314

95% Confidence Interval

Lower Bound Upper Bound
.03094
.04972
.00161
.02039
.01261
.03139
-.00039
.01839
-.00072
.01806
.00378
.02256
-.04972
-.03094
-.03829
-.02038
-.02729
-.00938
-.04029
-.02238
-.04062
-.02271
-.03612
-.01821
-.02039
-.00161
.02038
.03829
.00205
.01995
-.01095
.00695
-.01129
.00662
-.00679
.01112
-.03139
-.01261
.00938
.02729
-.01995
-.00205
-.02195
-.00405
-.02229
-.00438
-.01779
.00012
-.01839
.00039
.02238
.04029
-.00695
.01095
.00405
.02195
-.00929
.00862
-.00479
.01312
-.01806
.00072
.02271
.04062
-.00662
.01129
.00438
.02229
-.00862
.00929
-.00445
.01345
-.02256
-.00378
.01821
.03612
-.01112
.00679
-.00012
.01779
-.01312
.00479
-.01345
.00445

42

T3

(J) kelompok

kontrol positif

kontrol negative

pembanding Na 25
mg

pembanding Na 50
mg

uji Daun

uji buah

uji kombinasi

Mean
Difference (IJ)

kontrol negatif
pembanding Na 25 mg
pembanding Na 50 mg
uji Daun
uji buah
uji kombinasi
kontrol positif
pembanding Na 25 mg
pembanding Na 50 mg
uji Daun
uji buah
uji kombinasi
kontrol positif
kontrol negatif
pembanding Na 50 mg
uji Daun
uji buah
uji kombinasi
kontrol positif
kontrol negatif
pembanding Na 25 mg
uji Daun
uji buah
uji kombinasi
kontrol positif
kontrol negatif
pembanding Na 25 mg
pembanding Na 50 mg
uji buah
uji kombinasi
kontrol positif
kontrol negatif
pembanding Na 25 mg
pembanding Na 50 mg
uji Daun
uji kombinasi
kontrol positif
kontrol negatif
pembanding Na 25 mg
pembanding Na 50 mg
uji Daun
uji buah

Std. Error

.044167*
.011167*
.022500*
.017667*
.009167
.014167*
-.044167*
-.033000*
-.021667*
-.026500*
-.035000*
-.030000*
-.011167*
.033000*
.011333*
.006500
-.002000
.003000
-.022500*
.021667*
-.011333*
-.004833
-.013333*
-.008333
-.017667*
.026500*
-.006500
.004833
-.008500
-.003500
-.009167
.035000*
.002000
.013333*
.008500
.005000
-.014167*
.030000*
-.003000
.008333
.003500
-.005000

Sig.

.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484

95% Confidence Interval

Lower
Upper
Bound
Bound
.000
.03303
.05530
.049
.00003
.02230
.000
.01137
.03363
.003
.00653
.02880
.104
-.00197
.02030
.014
.00303
.02530
.000
-.05530
-.03303
.000
-.04413
-.02187
.000
-.03280
-.01053
.000
-.03763
-.01537
.000
-.04613
-.02387
.000
-.04113
-.01887
.049
-.02230
-.00003
.000
.02187
.04413
.046
.00020
.02247
.244
-.00463
.01763
.718
-.01313
.00913
.588
-.00813
.01413
.000
-.03363
-.01137
.000
.01053
.03280
.046
-.02247
-.00020
.384
-.01597
.00630
.020
-.02447
-.00220
.138
-.01947
.00280
.003
-.02880
-.00653
.000
.01537
.03763
.244
-.01763
.00463
.384
-.00630
.01597
.130
-.01963
.00263
.528
-.01463
.00763
.104
-.02030
.00197
.000
.02387
.04613
.718
-.00913
.01313
.020
.00220
.02447
.130
-.00263
.01963
.368
-.00613
.01613
.014
-.02530
-.00303
.000
.01887
.04113
.588
-.01413
.00813
.138
-.00280
.01947
.528
-.00763
.01463
.368
-.01613
.00613

43

T3

(J) kelompok

Mean
Difference (IJ)

Std. Error

kontrol negatif
.044167*
pembanding Na 25 mg
.011167*
pembanding Na 50 mg
.022500*
uji Daun
.017667*
uji buah
.009167
uji kombinasi
.014167*
kontrol negative
kontrol positif
-.044167*
pembanding Na 25 mg
-.033000*
pembanding Na 50 mg
-.021667*
uji Daun
-.026500*
uji buah
-.035000*
uji kombinasi
-.030000*
pembanding Na 25 kontrol positif
-.011167*
mg
kontrol negatif
.033000*
pembanding Na 50 mg
.011333*
uji Daun
.006500
uji buah
-.002000
uji kombinasi
.003000
pembanding Na 50 kontrol positif
-.022500*
mg
kontrol negatif
.021667*
pembanding Na 25 mg
-.011333*
uji Daun
-.004833
uji buah
-.013333*
uji kombinasi
-.008333
uji Daun
kontrol positif
-.017667*
kontrol negatif
.026500*
pembanding Na 25 mg
-.006500
pembanding Na 50 mg
.004833
uji buah
-.008500
uji kombinasi
-.003500
uji buah
kontrol positif
-.009167
kontrol negatif
.035000*
pembanding Na 25 mg
.002000
pembanding Na 50 mg
.013333*
uji Daun
.008500
uji kombinasi
.005000
uji kombinasi
kontrol positif
-.014167*
kontrol negatif
.030000*
pembanding Na 25 mg
-.003000
pembanding Na 50 mg
.008333
uji Daun
.003500
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB
kontrol positif

Sig.

.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484
.005484

95% Confidence Interval

Lower
Upper
Bound
Bound
.000
.03303
.05530
.049
.00003
.02230
.000
.01137
.03363
.003
.00653
.02880
.104
-.00197
.02030
.014
.00303
.02530
.000
-.05530
-.03303
.000
-.04413
-.02187
.000
-.03280
-.01053
.000
-.03763
-.01537
.000
-.04613
-.02387
.000
-.04113
-.01887
.049
-.02230
-.00003
.000
.02187
.04413
.046
.00020
.02247
.244
-.00463
.01763
.718
-.01313
.00913
.588
-.00813
.01413
.000
-.03363
-.01137
.000
.01053
.03280
.046
-.02247
-.00020
.384
-.01597
.00630
.020
-.02447
-.00220
.138
-.01947
.00280
.003
-.02880
-.00653
.000
.01537
.03763
.244
-.01763
.00463
.384
-.00630
.01597
.130
-.01963
.00263
.528
-.01463
.00763
.104
-.02030
.00197
.000
.02387
.04613
.718
-.00913
.01313
.020
.00220
.02447
.130
-.00263
.01963
.368
-.00613
.01613
.014
-.02530
-.00303
.000
.01887
.04113
.588
-.01413
.00813
.138
-.00280
.01947
.528
-.00763
.01463

44

T4

(J) kelompok

Mean
Difference
(I-J)
Std. Error
*
kontrol positif
kontrol negatif
.050000
.005638
pembanding Na 25 mg
.015833*
.005638
pembanding Na 50 mg
.026667*
.005638
*
uji Daun
.024333
.005638
uji buah
.015000*
.005638
*
uji kombinasi
.020000
.005638
kontrol negatif
kontrol positif
-.050000*
.005638
pembanding Na 25 mg
-.034167*
.005638
pembanding Na 50 mg
-.023333*
.005638
uji Daun
-.025667*
.005638
uji buah
-.035000*
.005638
uji kombinasi
-.030000*
.005638
pembanding Na 25 mg kontrol positif
-.015833*
.005638
*
kontrol negatif
.034167
.005638
pembanding Na 50 mg
.010833
.005638
uji Daun
.008500
.005638
uji buah
-.000833
.005638
uji kombinasi
.004167
.005638
pembanding Na 50 mg kontrol positif
-.026667*
.005638
kontrol negatif
.023333*
.005638
pembanding Na 25 mg
-.010833
.005638
uji Daun
-.002333
.005638
uji buah
-.011667*
.005638
uji kombinasi
-.006667
.005638
uji Daun
kontrol positif
-.024333*
.005638
kontrol negatif
.025667*
.005638
pembanding Na 25 mg
-.008500
.005638
pembanding Na 50 mg
.002333
.005638
uji buah
-.009333
.005638
uji kombinasi
-.004333
.005638
uji buah
kontrol positif
-.015000*
.005638
kontrol negatif
.035000*
.005638
pembanding Na 25 mg
.000833
.005638
pembanding Na 50 mg
.011667*
.005638
uji Daun
.009333
.005638
uji kombinasi
.005000
.005638
uji kombinasi
kontrol positif
-.020000*
.005638
*
kontrol negatif
.030000
.005638
pembanding Na 25 mg
-.004167
.005638
pembanding Na 50 mg
.006667
.005638
uji Daun
.004333
.005638
uji buah
-.005000
.005638
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25 mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB

95% Confidence Interval

Sig. Lower Bound Upper Bound
.000
.03855
.06145
.008
.00439
.02728
.000
.01522
.03811
.000
.01289
.03578
.012
.00355
.02645
.001
.00855
.03145
.000
-.06145
-.03855
.000
-.04561
-.02272
.000
-.03478
-.01189
.000
-.03711
-.01422
.000
-.04645
-.02355
.000
-.04145
-.01855
.008
-.02728
-.00439
.000
.02272
.04561
.063
-.00061
.02228
.141
-.00295
.01995
.883
-.01228
.01061
.465
-.00728
.01561
.000
-.03811
-.01522
.000
.01189
.03478
.063
-.02228
.00061
.681
-.01378
.00911
.046
-.02311
-.00022
.245
-.01811
.00478
.000
-.03578
-.01289
.000
.01422
.03711
.141
-.01995
.00295
.681
-.00911
.01378
.107
-.02078
.00211
.447
-.01578
.00711
.012
-.02645
-.00355
.000
.02355
.04645
.883
-.01061
.01228
.046
.00022
.02311
.107
-.00211
.02078
.381
-.00645
.01645
.001
-.03145
-.00855
.000
.01855
.04145
.465
-.01561
.00728
.245
-.00478
.01811
.447
-.00711
.01578
.381
-.01645
.00645

45

T5

(J) kelompok

Mean
Difference
(I-J)
Std. Error
*
kontrol positif
kontrol negatif
.050833
.006850
pembanding Na 25 mg
.020000*
.006850
pembanding Na 50 mg
.031167*
.006850
*
uji Daun
.023333
.006850
uji buah
.015333*
.006850
*
uji kombinasi
.024167
.006850
kontrol negatif
kontrol positif
-.050833*
.006850
pembanding Na 25 mg
-.030833*
.006850
pembanding Na 50 mg
-.019667*
.006850
uji Daun
-.027500*
.006850
uji buah
-.035500*
.006850
uji kombinasi
-.026667*
.006850
pembanding Na 25 kontrol positif
-.020000*
.006850
*
mg
kontrol negatif
.030833
.006850
pembanding Na 50 mg
.011167
.006850
uji Daun
.003333
.006850
uji buah
-.004667
.006850
uji kombinasi
.004167
.006850
pembanding Na 50 kontrol positif
-.031167*
.006850
mg
kontrol negatif
.019667*
.006850
pembanding Na 25 mg
-.011167
.006850
uji Daun
-.007833
.006850
uji buah
-.015833*
.006850
uji kombinasi
-.007000
.006850
uji Daun
kontrol positif
-.023333*
.006850
kontrol negatif
.027500*
.006850
pembanding Na 25 mg
-.003333
.006850
pembanding Na 50 mg
.007833
.006850
uji buah
-.008000
.006850
uji kombinasi
.000833
.006850
uji buah
kontrol positif
-.015333*
.006850
kontrol negatif
.035500*
.006850
pembanding Na 25 mg
.004667
.006850
pembanding Na 50 mg
.015833*
.006850
uji Daun
.008000
.006850
uji kombinasi
.008833
.006850
uji kombinasi
kontrol positif
-.024167*
.006850
*
kontrol negatif
.026667
.006850
pembanding Na 25 mg
-.004167
.006850
pembanding Na 50 mg
.007000
.006850
uji Daun
-.000833
.006850
uji buah
-.008833
.006850
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25 mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB

95% Confidence Interval

Sig. Lower Bound Upper Bound
.000
.03693
.06474
.006
.00609
.03391
.000
.01726
.04507
.002
.00943
.03724
.032
.00143
.02924
.001
.01026
.03807
.000
-.06474
-.03693
.000
-.04474
-.01693
.007
-.03357
-.00576
.000
-.04141
-.01359
.000
-.04941
-.02159
.000
-.04057
-.01276
.006
-.03391
-.00609
.000
.01693
.04474
.112
-.00274
.02507
.630
-.01057
.01724
.500
-.01857
.00924
.547
-.00974
.01807
.000
-.04507
-.01726
.007
.00576
.03357
.112
-.02507
.00274
.261
-.02174
.00607
.027
-.02974
-.00193
.314
-.02091
.00691
.002
-.03724
-.00943
.000
.01359
.04141
.630
-.01724
.01057
.261
-.00607
.02174
.251
-.02191
.00591
.904
-.01307
.01474
.032
-.02924
-.00143
.000
.02159
.04941
.500
-.00924
.01857
.027
.00193
.02974
.251
-.00591
.02191
.206
-.00507
.02274
.001
-.03807
-.01026
.000
.01276
.04057
.547
-.01807
.00974
.314
-.00691
.02091
.904
-.01474
.01307
.206
-.02274
.00507

46

T24

(J) kelompok

Mean
Difference
(I-J)
kontrol positif
kontrol negatif
.033333*
pembanding Na 25 mg
.009167
pembanding Na 50 mg
.016667*
uji Daun
.018000*
uji buah
.009167
uji kombinasi
.014167*
kontrol negatif
kontrol positif
-.033333*
pembanding Na 25 mg
-.024167*
pembanding Na 50 mg
-.016667*
uji Daun
-.015333*
uji buah
-.024167*
uji kombinasi
-.019167*
pembanding Na 0,45 kontrol positif
-.009167
mg/kgBB
kontrol negatif
.024167*
pembanding Na 50 mg
.007500
uji Daun
.008833
uji buah
.000000
uji kombinasi
.005000
pembanding Na 0,9
kontrol positif
-.016667*
mg/kgBB
kontrol negatif
.016667*
pembanding Na 25 mg
-.007500
uji Daun
.001333
uji buah
-.007500
uji kombinasi
-.002500
uji Daun
kontrol positif
-.018000*
kontrol negatif
.015333*
pembanding Na 25 mg
-.008833
pembanding Na 50 mg
-.001333
uji buah
-.008833
uji kombinasi
-.003833
uji buah
kontrol positif
-.009167
kontrol negatif
.024167*
pembanding Na 25 mg
.000000
pembanding Na 50 mg
.007500
uji Daun
.008833
uji kombinasi
.005000
uji kombinasi
kontrol positif
-.014167*
kontrol negatif
.019167*
pembanding Na 25 mg
-.005000
pembanding Na 50 mg
.002500
uji Daun
.003833
uji buah
-.005000
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB

95% Confidence Interval

Std.
Error
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061
.005061

Sig.
.000
.079
.002
.001
.079
.008
.000
.000
.002
.005
.000
.001
.079
.000
.147
.090
1.000
.330
.002
.002
.147
.794
.147
.624
.001
.005
.090
.794
.090
.454
.079
.000
1.000
.147
.090
.330
.008
.001
.330
.624
.454
.330

Lower Bound
Upper Bound
.02306
.04361
-.00111
.01944
.00639
.02694
.00773
.02827
-.00111
.01944
.00389
.02444
-.04361
-.02306
-.03444
-.01389
-.02694
-.00639
-.02561
-.00506
-.03444
-.01389
-.02944
-.00889
-.01944
.00111
.01389
.03444
-.00277
.01777
-.00144
.01911
-.01027
.01027
-.00527
.01527
-.02694
-.00639
.00639
.02694
-.01777
.00277
-.00894
.01161
-.01777
.00277
-.01277
.00777
-.02827
-.00773
.00506
.02561
-.01911
.00144
-.01161
.00894
-.01911
.00144
-.01411
.00644
-.01944
.00111
.01389
.03444
-.01027
.01027
-.00277
.01777
-.00144
.01911
-.00527
.01527
-.02444
-.00389
.00889
.02944
-.01527
.00527
-.00777
.01277
-.00644
.01411
-.01527
.00527

47

T30

(J) kelompok

Mean
Difference
(I-J)
Std. Error
*
kontrol positif
kontrol negatif
.025833
.004521
pembanding Na 25 mg
.011667*
.004521
pembanding Na 50 mg
.015000*
.004521
*
uji Daun
.012833
.004521
uji buah
.014167*
.004521
*
uji kombinasi
.017500
.004521
kontrol negatif
kontrol positif
-.025833*
.004521
pembanding Na 25 mg
-.014167*
.004521
pembanding Na 50 mg
-.010833*
.004521
uji Daun
-.013000*
.004521
uji buah
-.011667*
.004521
uji kombinasi
-.008333
.004521
pembanding Na 25 mg kontrol positif
-.011667*
.004521
*
kontrol negatif
.014167
.004521
pembanding Na 50 mg
.003333
.004521
uji Daun
.001167
.004521
uji buah
.002500
.004521
uji kombinasi
.005833
.004521
pembanding Na 50 mg kontrol positif
-.015000*
.004521
kontrol negatif
.010833*
.004521
pembanding Na 25 mg
-.003333
.004521
uji Daun
-.002167
.004521
uji buah
-.000833
.004521
uji kombinasi
.002500
.004521
uji Daun
kontrol positif
-.012833*
.004521
kontrol negatif
.013000*
.004521
pembanding Na 25 mg
-.001167
.004521
pembanding Na 50 mg
.002167
.004521
uji buah
.001333
.004521
uji kombinasi
.004667
.004521
uji buah
kontrol positif
-.014167*
.004521
kontrol negatif
.011667*
.004521
pembanding Na 25 mg
-.002500
.004521
pembanding Na 50 mg
.000833
.004521
uji Daun
-.001333
.004521
uji kombinasi
.003333
.004521
uji kombinasi
kontrol positif
-.017500*
.004521
kontrol negatif
.008333
.004521
pembanding Na 25 mg
-.005833
.004521
pembanding Na 50 mg
-.002500
.004521
uji Daun
-.004667
.004521
uji buah
-.003333
.004521
*. The mean difference is significant at the 0.05 level.
- Pembanding natriuu diklofenak 25 mg = 2,25mg/kgBB
- Pembanding natrium diklofenak 50 mg = 4,5mg/kgBB

95% Confidence Interval

Sig. Lower Bound Upper Bound
.000
.01666
.03501
.014
.00249
.02084
.002
.00582
.02418
.007
.00366
.02201
.003
.00499
.02334
.000
.00832
.02668
.000
-.03501
-.01666
.003
-.02334
-.00499
.022
-.02001
-.00166
.007
-.02218
-.00382
.014
-.02084
-.00249
.074
-.01751
.00084
.014
-.02084
-.00249
.003
.00499
.02334
.466
-.00584
.01251
.798
-.00801
.01034
.584
-.00668
.01168
.205
-.00334
.01501
.002
-.02418
-.00582
.022
.00166
.02001
.466
-.01251
.00584
.635
-.01134
.00701
.855
-.01001
.00834
.584
-.00668
.01168
.007
-.02201
-.00366
.007
.00382
.02218
.798
-.01034
.00801
.635
-.00701
.01134
.770
-.00784
.01051
.309
-.00451
.01384
.003
-.02334
-.00499
.014
.00249
.02084
.584
-.01168
.00668
.855
-.00834
.01001
.770
-.01051
.00784
.466
-.00584
.01251
.000
-.02668
-.00832
.074
-.00084
.01751
.205
-.01501
.00334
.584
-.01168
.00668
.309
-.01384
.00451
.466
-.01251
.00584

48

Lampiran 9
PENGUJIAN AKTIVITAS ANTIINFLAMASI

T0

T1

T2

T3

49

T4

T5

T24

T30

Gambar 10. 8 volume uji aktivitas antiinflamasi pada telapak kaki tikus