FINAL MOMENT PRE EXAM

25




PRESENTED BY
DR_WAEL MOHAMMED
< FOR U > GLORY MOM
G^OO^D LUCK
DATE OF PUPLISHING: 24-9-2015
2

HEMATOLOGY
Give 4 Causes Of Microcytic
Anaemia
Iron deficiency anaemia1
Thalassemia2
Sideroblastic anaemia3
Led posioning4
Give Specific Indication Of
Surgery In
Hereditary
Spherocytosis

Splenectomy For Rx of 1
anaemia
Cholecystoectomy For 2
Gallstone
Simple C/P Of ITP, Aplastic
Anaemia&ALL
ITP
Healthy
No splenomegaly
Aplastic a
Serious ill
No splenomegaly
ALL
Serious ill
Splenomegaly
Give 5 Causes Of Macrocytic
Anaemia
B12 deficiency1
Folate deficiency2
Hypothyrodism3
Liver dz4
Alcoholism5
Skin Sign In Dx Anaemia
JaundiceHemolysis
PetechiaeALL
Vitiligo Pernicious
Cafe au laitFanconi
KoilonychiaIDA
ClubbingIBD

In Iron Deficiency Anaemia

Hb
PCV
MCV
MCH
Ferritin
S.Iron
RCW
TIBC
Transferrin
Thrombocytosis
Microcytic
Hypochromic
What Is Most Sensitive Test To
Dx Iron Deficiency Anaemia
Low serum ferritin
Symptoms Linked ToIronDeficiency Anemia
Depression
Angina
DysphagiaEsophageal Webs
Plummer-Vinson syndrome
Restless legs syndrome
Indications for IV iron:
intolerant to oral
absolute non compliance
high iron requirement
GI malabsorption
Iron posioning May Lead
To
Haematemesis
Radiopaque pills on x-ray
LaterIntestinal stricture
Give 3 Indication Of Bone
Marrow Transplantation
Thalassemia1

ALL2

Aplastic anaemia3

B.Thalassaemia major
Autos.Recessive
Synthesis of B.globin
Hypochromic+Microcytic
S.Iron
Need:
HB.vaccin
Desferrioxamin
Folate
In B-Thalassemia major
Serum iron
Serum ferrtin
Hb F
Hb A2
MCH
MCHC
Iron binding capacity
Anisocytosis + poikilocytosis
Hormonal disturbance in
Thalassemia
Blood transfussionIron
overload
Hypogonadism1
Hypothyroidism2
DM3
Growth hormone Growth4
Substant GiveBenifit In
Thalassemia Major
Vitamin C Iron excretion in 1
urin by deferoxamin
Folic acid2
Tea Iron absorption3
Indication Of Splenectomy In
B.Thalssemia Major
Or Frequent Blood 1
Transfusion
Hypersplenism2
Mechanical DiscomfortVery 3
Larg Splen

Steps For Prevention Of

Complications Of SCA
Vaccination
Preventive antibiotics
Blood transfusion
Hydroxyurea
Bone marrow transplant

Major presentation of VasoOcclusive Cresis In SCA

Painful crisis1
Priapism2
Stroke3
Acute chest syndrome4

Give 5 Bad prognostic

Feature of ALL
Male1
Age <1 or > 10y2
WBC >50,0003
CNS +Testes involve4
Philadelphia chromosome5

What Is Role Of
Hydroxyurea In SCA

HbF1
SCA Complications2
Frequency of painful 3
crises
Blood transfusion4

Give 4Immunological dz
Causes
Lymphadenopathy
SLE1
Felty's syndrome2
Still's disease3
:Drugs4
Hydantoin
Hydralazine
Allopurinol

Give 3 Conditions In Which

Increase Risk Of
Leukemia
Down syndrome1
Bloom syndrome2
Ataxia-telangiectasia3

Causes Of Abdominal Pain In

SCA
Seqestration cresis
Gall stone
Mesentric thrombosis
Peritonitis
Pancreatitis
UTI
Referr pain
Advice To Patient With
S.C.A
Avoid dehydration1
Avoid infection2
Avoid tight clothing3
Avoid cold4
Avoid ice cold food5
Vaccination6
4 Types OfCresis In
SCA
Vaso-occlusive crisis1
Aplastic crisis2
Sequestration crisis3
Haemolytic crisis4
What Is Vaccinatuon Need
In
SCA
Haemophilus influenzae
vaccine
Pneumococcal conjugate
vaccine
Pneumococcal
polysaccharide vaccine

Give 10 Non Malignant Causes

Of
Lymphocytosis

EBV
CMV
Varicella
HIV
TB
Pertussis
Syphilis
Brucellosis
Typhoid
Toxoplasmosis
Give 2Chemotherapy Drugs
CausesCardiomyopathy
As Side Effect
Cyclophosamide1
Doxorubicine2
Causes of Massive
splenomegly
Myelofibrosis
Chronic Myeloid Leukemia
Malaria
Kala-Azar leishmania
Give 3 Causes OfCombs Test
+VeHaemolytic Anaemia
Autoimmune haemolytic 1
anaemia
Rh isoimmunization2
Incompatable blood 3
transfussion

LeukemiaVersus
Aplastic Anaemia
Leukemia
Pancytopnia
Hepatosplenomegaly
Aplastic anaemia
Pancytopnia
No hepatosplenomegaly
InHodgkin's dz
Past-History May be
EpsteinBarr virus infection
+Ve
ReedSternberg cells
characteristic histopathologic
finding
What Is Means By
B symptoms
Fever1

Night sweats2

Weight loss3

Seen in Hodgkin's lymphoma

: Important in
Prognosis
Staging of dz
What is feature of
Hypersplenism
Pancytopenia
Spleenomegaly
Presented with
Anaemia
Infection
Bleeding

Give 5Qualitative
Platelet Dysfunction
Von Willbrand dz1
Bernard-Soulier syndrome2
Glanzmann syndrome3
Uremia4
Liver dz5

Why G6PD assay may

Falsely normal in acute
haemolysis
Haemolysis of old RBC
Secondary to Reticulocytosis
Contain normal enzyme

Thrombosis and
thrombocytopenia
DIC
TTP
Antiphospholipid
syndrome APS
HIT
Malignancy
Name Most Common
Hereditary Coagulation dz

Von Willebrand dz

Types 1 & 2 Autosomal

dominant traits
Type 3 Autosomal
recessive

Give 3 Causes OfAnaemia

WithNo
Hepatosplenomegaly
Aplastic anaemia1

Chronic renal failure2

Blood loss3

Give 2 Conditions Other

Than ITP Cause
Prolonged
Bleeding time
Von Willebrand dz1
Haemollytic uraemic 2
syndrome
What Is Haematological
Changes in SLE
Haemolytic anaemia1
Coomb Test +Ve
Leukopenia2
Lymphopenia3
Thrombocytopenia4

What Is Uses Of
Erythropoietin
To Rx anaemia in
Chronic kidney disease
Cancer on chemotherapy
HIV on Rx
Uses of venesection :_polycythemia rubra vera
_ as end treatment of acute
pulmonary edema
_haemocrhromatosis
Cause Of Splenectomy
Cong. spherocytosis
Ch ITP
Trauma
SpleenTumor
Spleen abscess
Splenic artery Rupture
pregnant
SCA
Thalassemia
Give 4 dz Need
Peumococcal vaccine
Asplenic patient1

Patient with renal disease2

Patient with CSF leak3

Immunocompromised patient4

Give 7 DDx OfCausesOf

Eosinophilia
Asthma1
Drug allergy2
Parasite inf3
Polyarteritis nodosa4
Hodgkin dz5
Addison's dz6
SLE7
Asplenia
Absence of normal spleen
function
Cause:
Congenital
:Splenectomy
ITP
Spherocytosis
Thalassemia
:Autosplenectomy
SCA
Give 7 Causes Of
Low ESR
SCA
Leukemia
Congestive hear failure
Hyperviscosity
Hypofibrinogenemia
Low plasma protein
Polycythemia
Give Side-Effect Of Heparin
Heparin-induced 1
thrombocytopenia
Aminotransferase2
Hyperkalemia3
Alopecia4
OsteoporosisChronic use5

CARDIOLOGY
Give 5 Causes OfSinus
Bradycardia
Inferior MI1

Hypothyrodism2

Hypothermia3

Athletes4

ICP5

Adams-Stokes dz
Disorder of rhythm
Bradycardia
Syncope
With or without convulsions
Third-degree heart block on
ECG during attack
Give 5 Causes OfSinus
Tachycardia
Anemia1

Exercise2

Fever3

Anxiety4

Thyrotoxicosis5

Give 5 Causes OfLong PR

Interval
First degree heart block1

Acute rheumatic fever2

carditis
Hypokalemia3

Lyme disease4

Drugs5

ECG showing flattened P

waves; prolonged PR ;
widened QRS; and tall,
peaked T waves
characteristic of
hyperkalemia.
About P WaveIn The
ECG
P-Pulmonale
Peaked p wave in lead II
CausesRight atrial
enlargment
:Seen in
Chronic asthma
COPD

Managment of myocardial
infarction:
1 rest
2 oxygen 65%
3 crushed aspirn 300 mg
4 gtn angised sublingual
>>>ECG<<<
5 morphin iv 5 mg
6 plasil iv10 mg
7 fibrinolytic 100 mg
8 beta blocker
9 plavix
10 heparin 5000 iu
11 tahor
12 zantac
Inv : cardic enzym
Cbc
Random blood suger
Aptt
Dressler syndromePost.MI
syndrome
Delayed immune-mediated
Fever
Chest pain pleuritic
Pericarditis Pericardial
friction rub
WBC

St elevation of pericarditis
smile face smile
emoticon concave
St elevation of mi sad
face frown emoticon convex


nsaid ...
Variant Angina =
Prinzmetal's Angina
From coronary Vasospasm
Avoid Beta-blockers
Treat with dihydropyridine
CCB (i.e. nifedipine)

What Is Means
By Heart failure :
Heart can't pump enough blood
to meet the body needs

Right-side heart failure

Heart can't pump enough blood
to the lungs to pick up oxygen
What Is Mean By Cardiac
Cirrhosis

Chronic right sided heart failure

Leads toLiver
congestionLead to
Liver cirrhosis
How to differentite between
cardic asthma and nocturnal
bronchial asthma both occur at
sleep and both main symptoms
is cough by history :
First ask pt when the symptoms
develop after sleep:
If develop early after sleep it
cardic asthma due to increase
venous return to heart that lead
to lung congestion in pt with
heart failure
But if symptoms develop late at
night near 3_4 am it mean
nocturnal bronchial asthma is
due to decrease corticosteroid
due to diurnal variation
2nd Q is what you do to relife
symptoms :
Cardic asthmj relife by sitting
and taking air while nocturnal
asthma only by bronchodilator
Also by type of cough dry in
broncial asthma and wet frothy
in cardic asthma

Major Criteria Of Rhumatic

Fever
Polyarthritis1
CarditisSerious2
Subcutaneous nodule3
Erythema marginatum4
Sydenham's chorea Late5
Minor Criteria Of
Rhumatic Fever
Fever38.238.9 C1
Arthralgia2
ESR3
CRP4
WBC5
ECGPR interval6
Previous rheumatic fever7
Complications Of Rhumatic
Fever
Damage heart valves1
Commonly
MS
AS
HF2
Endocarditis3
Pericarditis4
Arrhythmias5
Sydenham Chorea
Seen 1-6mo after Rheumatic
Fever
Early signPoor handwriting
Purposeless involuntary
Movement
by stress
by sleep

Pathology OfBacterial
Endocarditis:
Portal of entery for bacteria1
EgTooth extraction
Abnormal Heart or valve2

Site OfEdema
: Early edema seen in
Priorbit + Legs
: Late edema seen in
Sacral + Genital

Vascular lesions seen in

Infective endocarditis
Stroke1
Splinter hg2
Janeway lesion3
Gangren of finger4
kidney & Splenic infarction5

Common Cause Of Pitting

Edema
Systemic dz1
Heart dz
Liver dz
Kidneys dz
Local dz2
Varicose veins
Thrombophlebitis

Single Best Investigation Test

For Detection Of Vegetation &
Abscess In Infective
Endocarditis

Transesophageal
Echocardiography
Name the Heart disease
Causes
Fingers Clubbing] [
Congenital cyanotic heart dz1
Subacute bacterial 2
endocarditis
Atrial myxoma3

Give 3 Histological Bodies In

Diagnosis Of dz

Aschoff bodies
Rhumatic fever
Negri bodies
Rabies
Lewy bodies
Parkinson's disease
Give 3 Cardiovascular causes Of
Haemoptysis
Congestive Heart Failure1
Severe Mitral stenosis2
Arteriovenous malformation3
Define Cyanosis :
Abnormal blue discoloration of
the skin & mucous membranes
Caused by in deoxygenated
Haemoglobin level to > 5 g/dL

Give 3 DDX OfNon-pitting

Edema
Lymphedema1
Pretibial myxedema2
)Sever Hypothyrodism(
Lipoedema3
Info :
Drugs cause lower limb edema
1.CCB
2.beta blocker
3.NSAID
Give 4 Signs Of
Cor Pulmonale

JVP1
Lt parasternal heave 2
Hepatomegaly 3
Bilateral leg edema 4
-all type of shock lead to low
volume pulse except septic
shock coz it cause vasodilation.
-high jvp without pulse >>>
superior vena cava obstruction
-syncope due to 3rd degree
heart block called adam stock
attack due to sever bradycardia
lead to low perfusion to brain

Give 2BruitsOccurs In
Patient With
Hypertension
Enlarged thyroid Bruits in
carotid arteries
Renal artery stenosis
Abdominal bruits
Antihypertensive Drugs Use
In Pregnancy
Labetolol
Methyldopa
Hydralazine
Nifedipine
ACE inhibitorReceptor
BlockerContraindicate
Best Rx For Hypertension
In DM Patient
ACE inhibeter
-toxic goiter : BP & heart
rate both increase
>>>nurogenic shock: both
decrease
> hypovolemic shock and
other shock : Bp=dec
HR=INCREASE
>Increase ICP : Bp=increase
hr= decrease
What is Indications of
Diuretics
Oedema1
Hypertension2
SIADS3
Nephrogenic diabetes 4
inspidus
Idiopathic hypercalciuria5

Give 2 Syndrome May

Associated With
Mitral Valve Prolapse
Marfan syndrome1
Ehler Danlos syndrome2

Give OneVitamin Deficiency

CauseHeart Failur
Vitamin B1Thiamine
Called Wet beriberi

Common Symptome Of
Aortic StenosisTraid of :

What Is AverageWeight Of
Human Heart

gm 300
Athletic reach 500 gm

1 Anginal chest pain

2 Dyspnea By activity
3 Fainting
Dont Forget The Notching Of
Ribs Is Sign Of Coarctation
Of Aorta & Due To
Collateral circulation
Type of Apex beat
TappingMS
TrustingAR
ForcefulAS
Impalpable
Emphysema
Pneumothorax
Dextrocardia
Obesity
Pericard effusion
D/D of emergency cases give to
them low molecular wt heparin
:
1_ unstable angina
2_ myocardial infarction
3_pulmonary embolism
4_DKA

What is uses of
Spironolactone
Resistant hypertension
Nephrotic syndrome
Congestive HF
Liver cirrhosis
Conn disease

Selenium Deficiency
Assiociated With:
Cardiomyopathy
What is most common
primary tumor seen in
Heart of
Adult
Myxoma

Kussmaul sign
ParadoxicalJVP on
inspiration
Seen in
Constrictive pericarditis
Restrictive cardiomyopathy
Tamponade
Pulm. embolism
Name Cardiac Causes Of
Ascitis Other Than
Heart Failure
Constrictive pericarditis
Beck's triad
Pathognomonic
for Cardiac Tamponade
Triad 1Bp 2Distended neck
veins 3Distant muffled heart
sounds
Jugular venous distention is
present in many patients with
cardiac tamponade, but may be
absent in those with severe
hypovolemia.
In patients with an idiopathic
pericardial effusion that has not
resolved by 3 months,
pericardiocentesis should be
performed.

ENDOCRINE
Fasting blood sugur
versus Random blood
sugar
Fasting After not eaten
anything for at least 8
hours
Random At any time of
the day
3 Main Types OfDM

Type 1 DM No enough 1
insulin
Type 2 DM Insulin 2
resistance
Gestational DM 3
Recover After birth of baby
What IsClassic
Symptoms Of
Type1DM
Polyuria
Polydipsia
Polyphagia
Unexplained weight loss

Give 8 Complications Of
DM
DKA
Infections
Nonketotic hyperosmolar
coma
CVS dz
Stroke
Ch.Renal Failure
Foot ulcer
Retinopathy
Why Infection In DM

Immune dysfunction
Micro- &macro-angiopathies+
neuropathy
Urin antibacterial activity
GIT & urinary dysmotility
What Is Main Symptom/Signs
OfDiabetes Insipidus

Traid Of
Polyuria1

Polydipsia2

Dehydration3

Range Value Of HbA1C

+Ve Test To Dx DM

FPG 7.0 mmol/l126 1

Normal 4% 5.6%
mg/dl
At risk of DM5.7% 6.4% OGTT Plasma glucose 11.1 2
> DM6.5% or
mmol/l (200 mg/dl) 2h after 75
g Oral glucose
Give 4 Infection
HbA1C 6.5%3
Common In
Why Patient WithDM
DM
Presented With
Mucormycosis1
Malignant otitis externa2
Diarrhea

Emphysematous 3
Autonomic nuropathy1
pyelonephritis
Infections2
Genital candidiasis4
Associated with Celiac dz3
Chronic pancreatitis4
Insulin Uses

What Is The Physiologic Stresses

Trigger DKA

Infection1
Truma2
MI3
Stroke4
Pancreatitis5
DrugsExample6
Corticosteroid
4 Causes Of Fall Potassium During
Rx Of DKA:
Insulin therapy
Correct of acidosis
Ongoing urinary loss
Dilutional effect of rehydration
Give 4 causes of
Ketonuria
DKA1
Hyperemesis gravidarum2
Fasting3
Exercise4
Indication Of Surgery For Rx Of
DM
Pancreas transplantType 1DM1
Kidney transplantEnd stage 2
renal dz
Weight loss surgeryRx3
Obesity
Give 5 Endocrine Causes Of
DM
Cushing syndrome1
Hyperthyroidism2
Acromegaly3
Pheochromocytoma4
Glucagonoma5
Give to Infections may Cause
DM
Cytomegalovirus infection1
Coxsackievirus B2

Rx of DM1
Type1&someType 2
With glucose for Rx Of 2
Hyperkalemia
Rx of hyperglycemia 3
induce by StressSurgury
& infection
What IsGlucagon
Peptide hormone
Produced by alpha cells of
Pancreas
Glucose in blood
Act opposite insulin
Give 4 Uses For
Metformin 1Type 2
DM 2Polycystic ovary
syndrome 3Gestational
diabetes 4Non-alcoholic
fatty liver dz
2 important MCQ about
conn's syndrom :
_ not cause edema even
with salt and water
retention
_ cause diastolic HTN not
systolic HTN
Give 2 Conditions
Presented With
Hypertension
Pluse Hypokalemia
Cushing syndrome1
Conn syndrome2
Give 3Endocrine
Causes Of
Carpal Tunnel
Syndrome
DM1
Acromegaly2
Hypothyrodism3

Blood Test Of
Hypothyroidism
T3 & T41

TSH2

Cholesterol3

LDH4

Lipoprotein5

S.Sodium 6

Antithyroid Peroxidase 7

autoimmune
Hyperthyroidism
Complications
Arrhythmia
Heart failure
Hypertension
Opthalmopathy
Osteoporosis
Thyrotoxic crisis
PR+Temp+delirium
What Is The BestInitial Test
For Dx OfHyper &
Hypothyrodism
TSH
Name TheEndocrain dz
Cause
Clubbing Of Fingers
Graves' disease Thyroid
acropachy
Therapeutic interventions for
thyroid storm are a
combination of antithyroid
drugs, iodine solution,
corticosteroids, -blockers.
>: The most common cause of
drug-induced thyrotoxicosis is
amiodarone
Give 3Endocraine dz
Causes Constipation
Hypothyrodism1

Hyperparathyrodism2

Diabetes inspidus3

10

GigantismVersus
Acromegaly
:Both Growth hormon
Gigantism Befor close of
epiphyseal growth plate
Acromegaly After close plate
Give 7 Feature In Acromegaly
Mandible overgrowth1
Deep thick voice2
Macroglossia3
Carpal tunnel syn4
BP5
Cardiomegaly6
Type 2 DM7
Give 3Blood InvestigationHelp
For Diagnosis Of
Cushing syndrome

Hypokalemia1
Hypernatremia2
Metabolic alkalosis3
MonitoringSide EffectOf Long
Use OfSteroidIn Child By
Clinical Examine
Bp
TempInfection
Wt
Hight
EyeCataract +Glaucoma
What Is 3 Major Stress
Hormons

Adrenaline1
Norepinephrine2
Cortisol3
Pheochromocytoma
Catecholamine by tumor of
adrenal gland in chromaffin cell
Headaches Common symptom
Sweating
S.Glucose
HR
BP
Pheochromocytomas 7 Hs
HypertensionHeadache
HypermetabolismHyperhidrosis
HyperglycemiaHypokalemia
Hypotension [with anesthesia]

Give 2 Most Important

Clinical Signs Of
Addison disease
Blood pressure + 1

Orthostatic hypotension
Skin hyperpigmentation 2

Dont Forget One Of

Presentation Of Addison
dz Is
Cravings For Salt Or Salty
Food
6 Blood Test In
Addison dz
Eosinophilia +
Lymphocytosis
Hyponatremia
Hypoglycemia
Hyperkalemia
Hypercalcemia
Metabolic acidosis
Give 1 Endocraine
disease Cause Small
HeartOn
CXR

Addison disease

Give 4 Indication For

Desmopresin (ADH)
Diabetes Inspidus1
Hemophilia2
Nacturnal Enuresis3
4Esophageal Varicess

9 Pituitary Hormone
Growth hormone1
TSH2
ACTH3
Prolactin4
Luteinizing hormone5
FSH6
Melanocyte stimulating 7
H
ADH8
9Oxytocin

Cause Of SIADH
CNS1
Meningitis
Encephalitis
Truma
Multipe sclerosis
Pulmonary2
Infection
Asthma
Lung cancers
Drugs eg Oxytocin3
3 Important Feature In
SIADH
:Traid
Antidiuretic hormone1
Fluid retention 2
HypervolemiaEdema
Dilutional hyponatremia3
Give 6 Conditions Associated
With SIADH
CNS infection
Cerebral edema
Brain tumor
Head truma
Lung dz
Positive pressure ventilation
Give 4 Causes Of
Increase ADH Level
Truma1

Pain2

Dehydration3

Hemorrhge4

Hypernatremia: causes6 D's:

Diuretics
Dehydration
Diabetes insipidus
Docs (iatrogenic)
Diarrhea
Disease: kidney, sickle cell,
ALL Endocraine dieases lead to
ammorrhea Excep t
hypothyrodism = menorrhagia
Enas Enas

11

What Is Main Symptom/Signs

OfDiabetes Insipidus
Traid Of
Polyuria1

Polydipsia2

Dehydration3

8 Complication Of Hypercalcemia
Dehydration1
BP2
Peptic ulcer3
Depression4
Renal stone5
Nephrocalcinosis6
Pancreatitis7
Fracture8
Milk-alkali syndrome
High blood calcium
Linked to
Taking in too much calcium To
prevent osteoporosis
Taking antacid contain Calcium
7 Hypoparathyroidism
Complications
Tetany1
Arrythemia2
Short stature3
Mental retardation4
Seizures5
Cataracts6
Dental malformation7
6Hypoparathyrodism
Test
Serum Ca1
S.phosphatase2
or normal alkalin phosphate3
1,25Hydroxycholcalcifrol4
Normal S.Mg5
PTH6
Trousseaus sign
Ve before other gross +
manifestations of hypocalcemia
Tetany
More sensitive fromChvostek sign

 hoarseness of
voice carpal tunnel
syndrom:
Hypothyroidism +
acromegally

hyperglycemia
(

)
ca po4

:
( 3ry hyperparathyroidism
+ acromegaly + CRF )..
Fatma Elmarghani

proximal ms weakness :
Thyrotoxicosis + cushing
syndrom + hyperaldosterolism
+ phoechromocytoma +
adrenal insufficiency +
acromegally + hypopitutarism

Adrenal Gland Hormon

Cortex
:Zona glomerulosa1
Aldosterone
:Fasciculata2
Cortisol
:Reticularis3
Androgen
Medulla2
Caticholamine

hypothyroidism

osteoporosis :
Thyrotoxicosis +
hyperparathyroidism +cushing
syndrom )

: hyperprolactinemia
Hypothyroidism + cushing
syndrom + acromegally

hypertension
( hypothyroidism
hypertension )
hypo
hypotension hypoglycemia
hypoadrenalism hypopitutarism ..
Fatma Elmarghani

Fatma Elmarghani

RESPIRATORY
Give 3 Signs Of
Sever Asthma
Cyanosis1
Tripod sitting position2
Inability to speak3

Give Infections Causes Of

Bronchiectasis
Whooping cough1
Measles2
TB3

2 Indication For Repated

CXR In Patient
With Asthma

No response to Rx1

Exclude Pneumothorax
Fever2

Exclude Pneumonia

InheritedCause Of
Bronchiectasis
Cystic fibrosis1
Kartagner dz2
Alpha 1-antitrypsin def3
Polycystic kidney dz4
Immunodeficiency5

Indications of Steroid in
TB
CNS TB1
Pericardial TB2
Adrenal TB3

What IsDrugsShould Be
Avoid InAsthma
Asprin
B.blocker
ACE inhibitors

What Is Means ByKartagener

syndrome
Autosomal recessive dz
Traid
Sinusitis1
Bronchiectasis2
Dextrocardia/situs inversus3

What Is Mean ByMeigs'

Syndrome
Triad of
Ascites1
Pleural effusion2
Benign ovarian tumor3

12

Give 3 Important Adverse Effect

Of
Inhaler Corticosteroid
Oral candidiasis1
Dysphonia2
Hoarse voice3

Respiratory Failure (RF)

: Type 1 RF
O2 tension
Co2 tension Normal or
: Type 2 RF
O2 tesion
Co2 tension
Respiratory Failure Type1
Cause
RestrictivePneumonia
ObstructiveAsthma
VascularPulm.embolism
C/F
Dyspnea
Cyanosis
Shallow breath
Causes Of Respiratory
Failure Type 2
COPD
Impair movement of chest
Narcotic poisoning
CVA
All causes of respiratory

Give 4CreteriaTo
DxCystic Fibrosis
Recurrent chest infection 1

2Chronic diarrhea
Ve Family history+3

Ve Sweat test+4

Give 2Bacterial Causes Of

Pneumonia In
Cystic Fibrosis

Staph.auerus1
Pseudomonas aeruginosa2
Respiratory problems in
Cystic fibrosis
Sinusitis1
Nasal polyp2
Pneumonia3
Bronchiectasis4
Hemoptysis5
Pulmonary hypertension6
2 Breath sound
Vesicular
Inspiratory phase>Expiratory
phas
No gap between 2 phas
Bronchial
Inspirat ph=Expirat ph
Gap between 2phas

Give 3 Cause Of
Emphysema
Tobacco smoke1
Air pollution2
Alpha-1-antitrypsin deficiency3
Give 2 Most Important
Presentation Of
Alpha 1-Antitrypsin
Deficiency
Emphysema1
Liver cirrhosis & liver failure2
About Terms In
Respiratory dz
Pink puffers Emphysema
Blue bloaters Chronic
bronchitis
Pneumococcal vaccination and
annual influenza vaccination
are recommended for all
patients with COPD.
Weight loss, muscle wasting,
and weakness are common in
severe COPD as a result of
deconditioning and
malnutrition.

What Is Initial Rx Of
TB
drugs - 4
Isoniazid1

Rifampin2

Pyrazinamide3

EitherEthambutol or 4

Streptomycin

6 Risk Factor For Nasal Polyp

Chronic sinus infection1
Asthma2
Hay fever3
Cystic fibrosis4
Churg-Strauss syndrome5
Aspirin allergy6

Important Feature In
Pneumothorax
Acute pleuritic chest pain
Dyspnea Not improved with
O2
JVP
Tracheal deviation
-Ve breath sounds

AntituberculosisDrugs
Side Effect
INH Peripheral
neuropathy
Rifampicin Flue like
illness
Ethambutol Optic neuritis

What is the Classic signs of

Pulmonary embolism in
ECG
S1Q3T3
Large S waveLead I
large Q waveLead III
Inverted T waveLead III

Causes Of Pneumothorax
Chest truma
Ruptur air bullae
COPD
Cystic fibrosis
Mech ventilater
TB
Marfan's
EhlersDanlos
Endometriosis

13

Main Classification Of
Pneumonia
Pathological1

Lobar
Interstitial
Bronchopneumonia
Causative agent2

Bacterial
Viral
Mycoplasma
Give 2 Bactreria Causes Of
Pneumatocele
Staph aureus
Klebsiella pneumonia
Give 7 Complication of
Mycoplasma Pneumonia
Jaundice
Myocarditis
Haemolytic anaemia
Platelet
DIC
Stevens-Johnson sy
Meningitis
Give 2 example of
Atypical Pneumonia
Mycoplasma pneumonia1
Chlamydia pneumonia2

Give 4CausesOfKussmals
Breathing
DKA1
Chronic renal failure2
Lactic acidosis3
Salicylate posioning4

Give 3 DDx OfPulmonary

Shadow In
CXR OfAIDS
Pateint

TB1

Pneumocystic carinii2

Kaposis sarcoma3

Name 6 Lung dz causes

clubbing of fingers
Lung cancer
Interstitial lung dz
Cystic fibriosis
Bronchioectasis
Lung abscess
Empyema
Treachea position Normal:
Slightly deviated to Rt
Pulmonary atelectasis:
Deviated to same side
Pneumothorax: Deviated to
oppsite side

What Is Means By
water-lily sign
Pathognomonic x-ray sign for
hydatid cyst infections
Classically seen in plain film
chest x-ray
Give 3 Common Causes Of
Nocturnal cough
Post-nasal drip1

Asthma2

Gastroesophageal reflux 3

]disease [GERD
Give 6Diseases Associated
With Pneumothorax
Give 3 Causes Of
COPD1
Cheyne_stokes Breathing
TB2
Sever cardiac failure1

Cystic fibrosis3
Nurological disorder Pontine 2

Bullae on lung4
haemorrhge
Sarcoidosis5
Narcotic drugs poisoning3

Marfan's syndrome6

CNS
What Is Most Common
MicroorganismAssociated
WithGuillain-Barre
syndrome(GBS)
Campylobacter

What Is Classical
Meningeal Signs
Nuchal rigidity1
Kernig's sign2
Brudzinski's sign3

4 Feature In GuillainBarr
syndrome
Ascending symmetrical
paralysis
SensationChange
or - Ve Tendon reflex
Breathing muscle paralysis

Give 2 Benifit Of Steroids

In Meningitis
Hearing loss1

Rates of death in TB 2

Meningitis

14

Give 5 Important Point In Rx

Meningitis
Antibiotics1
SteroidHIb2
Intravenous fluid3
Treatment of complication4
Surgury if need5
Give 2 Risk Factors
Susceptiblity To Meningioccocal
Meningitis
Deficiency in complement 1
C3,C5-C9
Inherited properdin deficiency2

6 DDx Of Unilateral
Headach
Migraine
Cluster headach
Trigeminal neuralgia
Refer pain
Sinus+ear+eye
Temporal arteritis
Local brain dz
Migrain prevention
Paropranol
NSAID
Ca ch blocker
Verapamil
Antidepressant
Fluxetine
Serotonin antagon
Cyproheptadin
Antiepilepsy
HeadachType
APrimary90%
Migrain1

Tension2

Cluster3

B2ndry10%
Brain Infection&Tumor1

Giant cell artertis2

Glaucoma3

Refer H4

DDx Of Most Common

Causes Of Headach In
Pregnancy
Tension headach1

Common one
Migrain2

Preeclampsia3

BenginICP4

Why the Headach in

Brain tumor by
Sleep
Cerebral edema Worsen
during sleep linked to
Mild hypoventilatione1
Lying position2

Give 5 Signs OfUpper Motor

NuronLesion
Spasticity Tone 1
2Weakness Pyramidal Type
Reflexes3
Up-going plantar response4
Clonus5

Symptoms OfParkinson's dz

Traid of
Tremor1
Rigidity2
Bradykinesia3
Slowness of movement

Give 4 Signs OfLower Motor

NeuronLesion
Muscle tone1
Muscles weakness &wasting2
Atrophy
Arreflexia3
Muscle fasciculations4

Sign & symptom of increase

ICP
Headach1
Vomiting2
Level of conciousness3
Puls rate4
Bp5
Diplopia6 Cranial nerve6
Papilloedema7

Ramsay Hunt syndrome

Herpes zoster infection affects
The Facial nerve near ears
Painful shingle rash
Facial paralysis
Hearing loss
.Horners Syndrome
Sympathetic trunk damage
CausesPancoast
.tumorestroke
Traid
Ptosis1
Miosis2
Anhydrosis Ipsilateral3
Give 4 Causes Of
Miosis
Horner's syndrome 21
Intracranil hemorrhage
Pontine hemorrhage
Organophosphate poisoning3
Opioids posioning4
Miller Fisher syndrome
Variant ofGuillainBarr
syndrome
Cranial nerveInvolvement
Triad of
Ataxia1
Ophthalamoplegia2
Areflexia3

15

7 C.N.SCauses Of
Vomiting
Encephalitis1
Meningitis2
Migraine3
Concussion4
Cerebral hemorrhage5
Brain tumor6
Benign ICP7
DDx Of Acute Flaccid Paralysis
Polio
Guillain-Barre
Diphtheria
Lyme dz
Transverse myelitis
Myasth.gravis
Botulism
Cord compression
HIV
4Important FeatureIn
Poliomyelitis
Asymmetrical paralysis
> Proximally
Deep tendon reflexes Absent
< Or
Sensation Not affected
Give 2Antibiotics Not Use
In Mysthenia Gravis
Ciprofloxacin1
Gentamicin2

Examination Of Patient
Take Phenytoin For
Gingival Hypertrophy
Hirsutism
AnaemiaMegaloblastic
Anaemia
Lymphadenopathy

What Significant Of
Examination Of Vital sign In
Dignosis Of
Cerebral edema
Pulse Rate = Bradycardia1
Blood presure = Hypertension2

Causes of bilateral facial

nerve palsy:sarcoidosis,
GBS , polio, lyme disease

Thiamine deficiency manifesting

as Wernicke encephalopathy :
Nystagmus Ophthalmoplegia
Ataxia Confusion
Signs Of Cerebellar Disorder
Ataxia Intension tremor
Dysmetria Hypotonia
Pupillary light reflex 2
Cranial Nerves Optic nerve:
Responsible for Afferent part
Oculomotor nerve: Responsible
for Efferent part

GIT
Give 2 First Clinical Feature
Seen In Celiac dz When Rx
With Gluten Free diet that
Indicate Improvement
Improvement of mood
Appetite
What Is TheTestUse
For MonitroringOf
Patient WithCeliac dz
On
Gluten Free Diet
Anti tissue
transglutaminase
Celiac dz Complication

Iron DA1
Lactose intolerance2
Vit. deficiency3
Osteoporosis4
Intestinal lymphoma5
Neurological symptome6
Diet avoid in
Celiac dz
Wheat
Rye
Barly
Oat

Feature Seen In Small Bowel

Biopsy Of Coeliac dz
Atrophy of villi Crypt
hyperplasia Lymphocyte
infiltration of crypts
What Is Skin Mainfestation
Of Ulcerative Colitis
Erythema nodosum1
Pyoderma gangrenosum2
Give 4Endocrine
Mainfestation Occurs In
Liver Cirrhosis
Spider nevi1

Palmar erythema2

Gynecomastia3

Hypogonadism4

Common Causes OfLiver

Cirrhosis In Adult Versus
Children
: Adult
Chronic alcoholism
: Children
Billary atresia
Wilson dz

16

Hand Examin In GIT dz

PallerGIT Hg
ClubbingIBD+cirrhosis
Plumer erythemiaLiver Cirrh
Flapping tremerLiver fail
KiolonychiahgIDA
Give 4 DDX Of
& Chronic Diarrhea
Finger Clubbing

Celiac dz1

Cytic fibrosis2

Crohns dz3

Ulcerative colitis4

Systemic dz Causes AphthousLike Ulceration

Behet's dz
Celiac dz
IBD
Reactive arthritis
ImmunocompromisHIV
Nutritional deficiency
Give 4Gastrointestinal
Causes Of
Fingers clubbing
Celiac dz1
Inflammatory bowel dz2
Liver cirrhosis3
Cystic fibrosis4

Complication Of Hepatitis
B
Hepatic failure
Chronic hepatitis
Cirrhosis
Liver cancer
Membranous GN
Aplastic anemia
Cryoglobulinemia
Which Form OfHepatitis
Is TheWorst
Hepatitis( C )Infection
Usually causes chronic dz1
No vaccine2
No cure3
Give 3 DDx OfTender
Enlarged Liver
Hepatitis A Hepatic
abscess Rt side heart
failure
Give 2 dz Associated With
Peptic Ulcer
Zollinger-Ellison syndrome
Crohns dz
Pautz jegher disease :
Ad_mulitple_familial
Rare or no malignancy
_common affect jejenum
Juvenile polyp:
Commnest cause of
bleeding perrectum in
children
No malignant change
So if in mcQ WANT NOT
MALIGNat disease choose
jevunile polyp
FAD:
Ad _malignant _>100 polyp

What Is Means ByBudd

Chiari syndrome
Occlusion of hepatic veins that
drain liver
Triad
Abdominal pain1
Ascites2
Hepatomegaly3
Deit avoid in
Wilson dz
Choclate
Nut
Shell fish
Liver
All these high copper diet
Spider NevusSpider
Angioma Disappears
when pressed on & comes back
when pressure releas Cause:
Normal Pregnancy
Hepatic dz
What is sign of Asciteson
physical examination
Flank bulgingBy inspection1
Shifting dullness2
)Fluid thril(Transmitted thril3
Disease & it is operation :
_ GERD >> _Nissan
fundiplication 360'
_ Besely 270 '
_pyloric stenosis > Ramsted
operation
_ Achalasia > Heler operation
_ plumer hydrostatic bag

5 Complications Of
Vomiting
Aspiration
Mallory-Weiss tear
Dehydration & electrolyte
Imbalance
Metabolic alkalosis
Tooth enamel damage

17

What Is The Most Common

Cause Of Traveler's
Diarrhea
Enterotoxigenic Escherichia coli
ETECis the most commonly
Isolated pathogen
What Is Mean By Parentral
Diarrhea

Diarrhea cause by disease out

side gastrointestinal tract
UTI
Otitis media
Tosilitis
Pneumonia
DDX of Villous Atrophy
Celiac
Giardia
HIV
TB
Immunodeficiency
Whipples
Cows milk allergy
Tropical sprue
Intes lymphoma
Crohns
Give 4 Causes of Morning
Vomiting

Pregnancy1
ICP 2
Migraine3
Food Poisoning4
Causes OfAbdominal
Distension
Flatus Gas
Faeces Constipation
Fat Obesity
Feotus Pregnancy
Fluid Ascitis

RHEUMATOLOGY
Neurological C/P In
Rhumatoid Arthritis
Peripheral neuropathy
Mononeuritis multiplex
Carpal tunnel syndrome
Atlanto-axial subluxation
3Lungs
Mainfestations In
Rhumatoid Arthritis
Lungs fibrosisLink to1

Drugs Methotrexate
Caplan's syndrome2

Pleural effusions3

5 Signs Of
ImprovementIn
Rheumatoid Arthritis
Morning stiffness
Good walk
Good hand grip
Joint swelling
Improvement Hb + ESR
Physical Examin In
Rhumatoid Arthritis
Swelling
Motion limitation
Deformity
Stiffness
Rhumatoid nodule
Extraarticular C/P
Tenderness
What Is Mean By
Felty's Syndrome

Traid of
Rheumatoid arthritis1
Splenomegaly2
Neutropenia3
May associated with
HLA-DR4
CREST syndrome:
Calcinosis Raynaud
phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasia

GiveSign& Symptome
Of Arthritis
Pain1
Swelling2
Redness3
Stiffness4
Joint movement5
Give 7 Viral dz may causes
Arthritis

Hepatitis A,B,C1
Rubella2
Mumps3
Parvovirus B194
Varcella zoster5
EBV6
Coxsackie viruse7
What Means ByReiter's
Syndrome
One form of reactive arthritis
Triad
Arthritis1
Non-gonococcal urethritis 2
3Conjunctivitis
Give Sign & Symptome Of
Arthritis

Pain1
Swelling2
Redness3
Stiffness4
Joint movement5
Gram-positive organisms are
the most common causes of
infectious arthritis, with
Staphylococcus aureus being
the most common infecting
agent
Monoarthritis differential
GHOST:
Gout
Haemarthrosis
Osteoarthritis
Sepsis
Trauma

8 Causes Of Butterfly

18

CNS Mainfestation of
SLE
Mental change
Seizure
Stroke
Optic neuritis
Peripheral neuropathy
Myopathy
Transverse myelitis
Chorea
Test To DxDrugs-Induced Lups

+Ve ANA1
+Ve Antihistone antibodies2
-Ve Double stranded DNA3
4 Major Causes OfDeath In
SLE
Renal failure1

Coronary artery dz2

Infections3

CNS complications4

What Is Causes Of Anaemia In

SLE
Bone marrow activity
RBC life span
Poor iron uptake
Drug S.ENSAID & steroid GIT
bleed
Hemolysis
Drugs Induce SLE
1Sulfonamide 2Hydralazine
3Procainamid 4Phenytoine
What is Investigation of SLE
& Neonatal Lupus
SLE
Anti ds- DNA1
Anti-Smith antibody2
Neonatal lupus
Anti Ro SSA1
Anti Ro SSB2

Rash
SLE1
Dermatomyositis2
Drug photosensetivitty3
Erysipelas4
Pellagra5
Rosacea6
Scarlet fever7
Sunburn8
Butterfly rash
Seen in SLE Not
Pathognomonic
Red&mild scal
On bridge of nose
Spares nasolabial fold
Macular+sharp edge
Not itchy
Give 3 Causes Of
Charcot JointOr
Nuropathic Joint
DM Most common
Syphilis Tabes
dorsalis Leprosy
Classification Of Lupus
Erythematosus
Four Types
Systemic1

Discoid2

Drug-induced3

Neonatal4

What IsClassic Triad

Of

HenochSchnlein Purpura
Purpura1

Arthritis2

Abdominal pain3

5 Example Of Type III (Immune

Complex) Reaction
SLE
Post strep Glumerulonephritis
Rheumatoid arthritis
Scleroderma
Sjgren's syndrom
Give 3 dz example of Type II
Reactions
Mysthenia gravis1
Grave dz2
Goodpasture syndrome3
D/D OF MORNING Stiffness ;
_rhumatoid arthritis
_Ankylosing spondolytis
_scleroderma
_polymylagia rheumatic
Action& 2Important Use
OfAllopurinol
Inhibitor of the enzyme
xanthine oxidase
Use
Gout and hyperuricemia 1
2Tumor lysis syndrome

Goodpasture syndrome
Anti-glomerular basement
antibody dz
Autoimmune dz
2 Feature
Pulmonary hemorrhage1
Glomerulonephritis2
Give 3 DDX Of C3
Level
SLE1
Post streptococcal 2
Glomerulonephritis
Bacterial endocarditis3
What Is Most Important
Investigation To Measure Bone
Density In
Osteoporosis
Dual - Energy X-ray
)Absorptiometry Scanning (DEXA
Ankylosing spondylitis is
characterized by progressive
inflammatory back pain and
stiffness; onset is between 20 and
30 years of age.
HLA-B27 is the strongest genetic
risk factor for spondyloarthritis;
95% of patients with ankylosing
spondylitis are HLA-B27 positive
Scleroderma
ScleroHard
DermaSkin
Autoimmune dz
Normal tissues replace with
dense thick scar tissue
In child affect mostlySkin

RENAL
Give 3Renal Causes
Of Polyuria
Chronic kidney dz 1
2Nephrogenic diabetes
insipidus
Fanconi's syndrome3

2Kidneys Mainfestation In
Rhumatoid Arthritis
Renal amyloidosis1
Rx with2
Penicillamine + Gold causes
Membranous nephropathy

19

Give 5 Complications of UTI

Recurrent infection
Sepsis
Urethral stricture
Kidney scarring
In prgnancy LBW &
Premature labour

Give 3 Syndrome
May Presented With
Hypokalemia
K )(
Cushing's syndrome

Conn syndrome

Bartter syndrome

Give 6 Feature InSever

Hypokalaemia
Flaccid paralysis1
Polydepsia2
Polyuria3
Paralytic ileus4
Hyporeflexia5
Cardiac arrythemia6
Give 8 Causes Of
Hyperkalaemia
Addison's dz1
Haemolysis2
Burns3
Diuretic4
Crush injuries5
Chemotherapy6
Taking potassium7
Tumor8
6 Medical Rx of
hyperkalaemia
Insulin +Glucose
Salbutamol inhaler
IV bicarbonate
Kayexalate
Loop diuretics
Furosemide
Hemodialysis
Oliguria
Urine output(UOP) <
Than 1 mL/kg/h in infant
(UOP) < Than 0.5 mL/kg/h
in Children
(UOP) < Than 400 mL daily
in Adult

4 Feature Of Nephrotic
Syndrome 1Proteinuria
2Hypoalbuminemia
3Hyperlipidaemia
4Generalized edema Start in
Face to Face

Give 3 Feature Linked To

Nephritic More Than
Nephrotic

Macroscopic haematuria1
Hypertension2
Raised serum creatinine3

Sign of complications in
Nephrotic sy
Abd tenderperitonitis
BPsepsis
RDSpulm. emboli
HematuriaRenal Vein
Thrombosis
FitStroke

Poststrepoccocal GN Versus
Nephrotic syndrome
Poststrep GN
Edema
Hematuria
Hypertension
Nephrotic
Edema
No hematuria
Normal BP

2 Types Of
Albuminuria
Microalbuminuriaexcretion
30 to 300 mg of albumin/24 hr
Macroalbuminuria
excretion > 300 mg of
albumin/24hr
Daily Chart ForNephrotic
SyndromePateint
WtEdema1
TempInfection2
BpHypovolaemia3
24h Urin collection4
24h Urin albumin measure5
What Is The Most Common
Cause of Chronic Renal Failure
In Adult
Diabetic nephropathy
Give Two Most common
Causes Of Chronic renal
failure
In Adult
Diabetic nephropathy1
Common 1
Hypertension2

20

Post-Streptococcal GlomeruloNephritis
Proliferative GN
Type III reaction
HematuriaTea colour
Edema
Oliguria
BP
ASO titre
C3
TB1
Meninigococcal meningitis2
What Is Cause Of Recurrent
Painless Haematuria That
Associated With Respiratory
Infections
IgA Nephropathy
4 Causes Of Anemia In
Chronic Renal Failure
Erythropoietin deficiency1
Hemolysis2
Bleeding Platelet 3
dysfunction
Loss of appetite4

INFECTIOUS
Give CD4 Count At Which
Severe Symptoms Of
:AIDS
Toxoplasmosis of brain
Candidiasis of esophagus
Kaposi's sarcoma
CD4 count < 200/l
What Is The Common
Malignancy In HIV
Children Non-Hodgkin
lymphoma
Adult Kaposi sarcoma
Give 4 Common
(CNS)Infection In AIDS
Toxoplasmosis1

CMV2

Cryptococcal3

TB4

HIV
Retrovirus
RNA virus
Single strand RNA virus
Infected CD4_T cell

What is most common cause of

Death in
Brucellosis
Endocarditis
Give Blood tests seen in
Brucellosis
Anaemia
Leukopenia
Elevation of AST and ALT
Positive Rose Bengal Test
Give Other Name Of
Brucellosis
Malta fever
4 IndicationsOfSteroid
In Infectious Mononucleosis

Airway obstruction1
Hemolytic anemia2
Thrombocytopenia3
CNS involvement4
What Is Serious complication of
Shigellosis
Haemolytic uremic syndrome

In Cholera
: Factor infection1

Type O blood group

Lowered gastric acidity
Antiacid drug
: Disease give protection2

Cystic fibrosis
:What dz Called
Black Death

Plague
Caused by Yersinia pestis
2 SeriousComplicationOf
Plasmodium
Falciparum

Cerbral malaria1
Black water fever2
Classic Signs & Symptoms Of
Measles
3 C1
Cough
Coryza
Conjunctivitis
Koplik's spots2
Pathognomonic

DERMATOLOGY
Erythema Infectioum
Fifth dz
Parvovirus B19
I.P4-14 days
Erythema mainly on
cheeks Slapped face
Rash is pruritic
Polyarthropathy
D/D of reccurent oral
genital ulcer;
_ Behcet ulcer (painful)
_Reiter's disease (painless)
_Syphilis (Painless)

Give 4 Sexually Transmitted dz

Causes
Lymphadenopathy
Lymphogranuloma venereum1
Secondary syphilis2
HIV infection3
Hepatitis B4

Pityriasis rosea
History of URTI
Single herald patch lesion
)cm 10(
Followed in 1 to 2 weeks by
ChrismasTree like body rash
Itching

Give 4 Disease Associated With (

Eczema )
Wiskoot Aldrich syndrom1
Lymphoma2
Celiac dz3
Histocytosis4

What Is The Most Common

Cause Of
Erythema Multiforme
Herpes simplex

21

2SignsInPsoriasis
:Auspitz's sign1
Pinpoint bleeding when
scale remove
:Koebner phenomenon2
Psoriatic lesion induce by
skin trauma
Give 4Medications
Aggravate Psoriasis
B-blockerPropranolol1
Lithium2
Antimalaria3
SAIDs: 4
ibuprofen+Naproxen

: What Is Means By
Hutchinson's Triad
Hutchinson's teeth (Notch1

)Incisors
Keratitis2

Deafness3

Seen in Congenital
Syphilis

Give 4 Causes OfCaf aulait

Spots
Nurofibromatosis1

Tuberous sclerosis2

Fanconi anaemia3

Mccune-Albright syndrome4

Give 7CausesOf
Hirsutism
PCOS1
Congent. adrenal 2
hyperplasia
Cushing's dz3
Acromegaly4
Adrenal , Ovarian tumor5
Obesity6
Drugs7

Cause Of Acanthosis
Nigricance
Obesity1
Malignancy2
Type 2 DM3
Polycystic ovary dz4
Hypothyroidism5
Cushing dz6
Acromegaly7
Drugs8
Toxic shock syndrome
Staph.aureus
Associat with tampon use
Fever
Erythematous rash
Skin desqumation
Shock
Multiple organ failure

PSYCHATRIC
Hypothyroidism
Associated With
Depression

In Schizophrenia , The Most

Common Type Of Hallucination
Is : - Auditory

Hyperthyroidism
Associated With Mania

While In Delirium Is : - Visual

Hyperparathyroidism
Associated With Anxiety
Role Of Benzodiazepine (
BDZ ) In Alcohol
Withdrawal : - To
Prevent Insomnia .. - To
Prevent Seizures ..
Benzodiazepine ( BDZ ) :
Is The Best Medication
Used In Treatment Of
Anxiety ..

Neuroleptic Malignant
Syndrome ( NMS ) Is A
Dangerous Side Effect Of
TYPICAL Anti-Psychotic
Drugs
Classical Tetrad Of NMS : Mental Changes - High
Temperature - Autonomic
Instability - Muscle Regidity
Management Of MNS : Admission - Stop Medication Supportive Measures Dantrolene - Bromocriptine
BDZ

22

Give 5 dz Associated With

Depression
Hypothyrodism1
Cushings disease2
Cancer3
Parkinsons disease4
HIV5
There Is A Strong Relationship
Between : Stroke In Left Side
Of Brain And Depression ..

- Depression Alone : MDD

- Depression + Mania : Bipolar
Disorder Type I
- Depression + Hypomania :
Bipolar Disorder Type II

Clozapine : Is Used In
Treatment Of Resistant
Cases Of Schizophrenia ..

Propranolol ( Inderal ) : Is Used

In Treatment Of Patient With
Akathesia ..

Serious Side Effect Of

Clozapine Is
Agranulocytosis , So You
Have To Start Gradually &
Do Routine CBC

Lithium side effects

LITHIUM:
Leukocytes Increased
(leukocytosis)
Tremors
Hypothyroidism
Increased Urine
Moms beware (teratogenic)

MIXED TOPICS
Tumor Lysis Syndrome
Seen 48-72 hr after
initiation of Cancer Rx
Hyperkalemia Early 1
Hyperuricemia
Hyperphosphatemia
Hypocalcemia
Causes of palmar
erythema:
1.physiological :
hyperdynamic circulation
>pregnancy<
2.pathological :
_thyrotoxicosis
_liver cirrhosis
_SLE
_R.A
_hypercapnia
3 Causes Of Beri Beri
Vi _B1) Deficiency (
Infant of mother 1

deficient of B1 with breast

feeding
Hyperemesis gravidarum2

Alcoholism3

Give 3 Causes Of
Hyperammonia
Liver dz1

Lactic acidosis2

Reye syndrome3

Give 3 Conditions Have Blue

Sclera

Osteogensis Imperfecta1
Murfan Syndrome2
Ehler Danlos Syndrome3
Give 4 dz Cause Fever
Pluse
Rigor
Malaria1
Kala azar2
Urinary tract infections 3
4Infective endocarditis
Eye sign in dz
DownBrushfiel spot
Wilson dzKayser-Fleisher
rings
Tuberous sclerosisLish nodule
Osteogenesis inperfectaBlue
sclera
DDx of Blue Sclerae
Phenylketonuria
Lowe syndrom
Types I+II osteogenesis
imperfecta
Ehler's danlos
Marfan
Pseudoxanthoma elasticum
Give 3 Toxins causes
Hypersalivation
Organophosphates 1
)(insecticide
Arsenic2
Mercury3

Give 4 dz Associated

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Metronidazole Use
Bactetr vaginosis
PID
Pseudomemb colitis
Rosacea
Intra-abdominal inf
Amoebia
Giardia
Trichomonus
Anaerobic bact
Why Ciprofloxacin Avoid In
Children & Old Age
Old age > 60y risk of
Tendinitis
Tendon rupture
Children Risk of
Arthropathy
Give 3ContraindicationFor
Gentamicin
Myasthenia gravis
Renal failure
Pregnancy
Give 6 [ Drugs ] Cause
Gingival Hypertrophy
Phenytoin1
Phenobarbital2
Lamotrigine3
Nifedipine4
Erythromycine5
Cyclosporine6
What is most common Microorganism isolated from Dog &
Cat bite
Pasteurella species

With
AmyloidosisAs
Complication
Rheumatoid arthritis
Chronic osteomyelitis
TB
Multiple myeloma

Give 6Types Of
Fever:
Continues1
Remittent2
Intermittent3
Undulant fever4
Relapsing fever5
Pel-Ebstein fever6

Disease With Other

Name
What Is Mean By Female
Viscersl leishmaniasis
Athlete Triad
Kala azar
Eating disorders Wt1
Infec mono.nucleosis
Amenorrhoea2
kissing disease
Osteoporosis Stress fracture3
Black water fever
falciparum malaria
Risk factor for Vit K deficiency
Newborn
Important Note Seen In
Liver dz
Schistosoma
Cystic fibrosis
Haematobium
Inflammatory bowel dz
Terminal hemturia1
Anticoagulant
Cystitis2
Drugs
Ureteritis3
Salicylate
ComplicationBladder 4
Barbiturate
cancer
RxPraziquantel5
Give the important
Give 3 Causes Of
Dry Mouth
Eyes &
Sjgren syndrome1

DM2

Sarcoidosis3

Some important MCQS

IN medicine :
A. The classification of
type of AF (paroxysmal,
persistent, or permanent)
does not affect the
decision to anticoagulate.

Diseases More Common In

Women
Thyroid dz
SLE
Osteoarthritis
Osteoporosis
Depression
Multiple Sclerosis
Migraine
Fibromyalgia
Dont Forget ThatNormal
PregnancyMay Associated
With
Aplastic anaemia

Plamer erythema

Psudotumor cereberi

Give 4 Infectious Diseases

In Adult Can Treated By
Doxycycline

Cholera1
Gonorrhea2
Lyme dz3
Malaria4

presentation of generalized
Tetanus

Trismus Lockjaw
Risus sardonicusFacial spasm
Opisthotonos

B. The primary therapy for

acromegaly is transsphenoidal
surgery to remove the causative
growth hormonesecreting
pituitary adenoma.
C . The gold standard for
diagnosis of primary sclerosing
cholangitis is cholangiography.

24

D. The most common cause of

drug-induced thyrotoxicosis is
amiodarone.
E. Radioactive iodine ablation is
the preferred treatment of toxic
multinodular goiter and toxic
adenoma.
F. Folate deficiency is more
common than vit B12 deficiency
in coeliac disease

Characterstic Drug Toxicities

Agranulocytosis

Clozapine

Aplastic Anemia

Chloramphenicol NSAIDs Benzene

Atropine-like Side Effects

Tricyclics

Cardiotoxicity

Doxorubicin Daunorubicin

Cartilage Damage in children

Fluoroquinolones (Ciprofloxacin & Norfloxacin)

Cinchonism

Quinidine

Coronary Steal Phenomenon

Dipyridamole

Corneal micro deposits

Amiodarone

Cough

ACE Inhibitors

Diabetes Insipidus

Lithium

Disulfiram-like effect

Metronidazole Sulfonylureas (1st generation)

Extrapyramidal Side Effects

Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)

Fanconis Syndrome

Tetracycline

Fatal Hepatotoxicity (necrosis)

Valproic Acid Halothane Acetaminophen

Gingival Hyperplasia

Phenytoin

Gray Baby Syndrome

Chloramphenicol

Gynecomastia

Cimetidine Azoles Spironolactone Digitalis Estrogen &

testosterone INH & ethionamide Clomiphine Phenytoin
Reserpine & Methyldopa

Hand Foot Syndrome

5Flurouracil (5-FU)

Hemolytic Anemia in

Sulfonamides Isoniazid Aspirin Ibuprofen Primaquine

G6PDdeficiency
Hemorrhagic Cystitis

Cyclophosphamide Ifosamide (Treat by Mesna &

Acetylcysteine Bladder Wash)

Hepatitis

Isoniazid

Hot Flashes, Flushing

Niacin Tamoxifen Ca++ Channel Blockers

Hypertension: Postural

Prazocin

Hypertension: Rebound

Clonidine withdrawal

Increased intra cranial tension (

Amiodarone Hypervitaminosis A OCPs Tetracycline

ICT)

Quinolones

Induce CP450

Barbiturates Phenytoin Carbamazepine Rifampin

Inhibit CP450

Cimetidine Erythromycin Ketoconazole

Isoniazid (INH) [remember CEKI]

Interstitial Nephritis

Methicillin NSAIDs (except Aspirin) Furosemide

Sulfonamides

Milk Alkali Syndrome

Calcium Carbonate (CaCo3)

25

Monday Disease

Nitroglycerin Industrial exposure tolerance during week

loss of tolerance during weekend headache, tach,
dizziness upon re-exposure

Nephrotoxicity

Cephaloridine Gentamycin Amphotericin

Orange Body Fluids

Rifampin

Osteoporosis

Heparin Corticosteroids

Pancreatitis

L-Asparginase Glucocorticoids

Photosensitivity

Lomefloxacin Pefloxacin

Positive Coombs Test

Methyldopa

Pulmonary Fibrosis

Bleomycin Amiodarone

Rabbit Syndrome (Perioral tremors)

Phenothiazines

Red Man Syndrome

Vancomycin (rapid IV)

Severe HTN with Tyramine

MAOIs

SLE- Drug Induced

Chloropromazine Hydralazine Isoniazid Methyldopa

[Anti Histone Antibody

Procainamide Quinidine [ remember CHIMP -Q]

Characteristic of this]
Tardive Dyskinesia

Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)

Tinnitus

Aspirin Quinidine

Torsades de Pontis

Terfanadine

THANX E.M.A FOR UR SUPPORT AND

GOOD LUCK
TOHA
TOHTY

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