PULMONARY

TUBERCULOSIS
ANINDYA .L. SIDARTA
03.011.034

DEFINITION

A highly contagious infection caused by

the bacterium called Mycobacterium
tuberculosis.

Tubercles (tiny lumps) are a

characteristic finding in TB.

ETIOLOGY
Mycobacterium
tuberculosis
Aerobic,
non
spore
forming,
non
motile,
facultative, intracellular.

EPIDEMIOLOGY

In 2007, the prevalence

of TB per 100,000 people
was highest in SubSaharan Africa, and was
also relatively high in
Asia

TB PATIENTS

Airborne Spreading

INFECTION

TB PATHOLOGY

SYMPTOMPATHOLOGY

DIAGNOSIS

Sputum culture
Tuberculin Skin Test
Chest Radiograph

Sputum Culture

The best method

Occur 1-8 weeks to provide results

Mantoux Tuberculin Skin Test

Screening
Put an antigen on a layer of the skin
If someone ever had a TB infection, in 2
days an antigen will reacts and causing a
red bump on skin.

Chest Radiograph

NORMAL

ACTIVE TB
PATIENT

TREATMENT FOR ACTIVE TB PATIENT

initial treatment 2HRZE ( 2 months)

Isoniazid (H) 5mg/kg per day

Rifampin (R) 5mg/kg per day
Pyrazinamid (Z) 25mg/kg per day
Ethambutol (E) 15mg/kg per day

Further treatment 4H3R3 (4 months)

Isoniazid (H) 10mg/kg three times a week

Rifampisin (R) 10mg/kg three times a week

TOTAL 6 MONTHS.