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  • Causes of Acute Pancreatitis!

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    Yui Phitchaya Monsintorn
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    The document summarizes various causes, drugs, and scoring systems related to acute pancreatitis. The main causes of acute pancreatitis are heavy alcohol intake and gallstones, while 15-25% of cases have no clear cause. Other potential causes include hyperlipidemia, abdominal trauma, certain drugs, infections, and anatomical anomalies. The document also lists mnemonics to remember drugs that can cause pancreatitis and factors in the Ranson criteria and HAPS scoring systems used to evaluate acute pancreatitis severity.

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    Keypoints for medical student exam during internal medicine rotation

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    Acute Pancreatitis

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    The document summarizes various causes, drugs, and scoring systems related to acute pancreatitis. The main causes of acute pancreatitis are heavy alcohol intake and gallstones, while 15-25% of cases have no clear cause. Other potential causes include hyperlipidemia, abdominal trauma, certain drugs, infections, and anatomical anomalies. The document also lists mnemonics to remember drugs that can cause pancreatitis and factors in the Ranson criteria and HAPS scoring systems used to evaluate acute pancreatitis severity.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    14 views1 page

    Causes of Acute Pancreatitis!

    Uploaded by

    Yui Phitchaya Monsintorn
    The document summarizes various causes, drugs, and scoring systems related to acute pancreatitis. The main causes of acute pancreatitis are heavy alcohol intake and gallstones, while 15-25% of cases have no clear cause. Other potential causes include hyperlipidemia, abdominal trauma, certain drugs, infections, and anatomical anomalies. The document also lists mnemonics to remember drugs that can cause pancreatitis and factors in the Ranson criteria and HAPS scoring systems used to evaluate acute pancreatitis severity.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 1

    Causes of acute pancreatitis!

    mostly = heavy alcohol intake, gallstone!


    15 - 25% are truly idiopathic!
    other causes!
    - hypercalcemia!
    - hyperlipidemia : chylomicronemia, hypertriglyceridemia or both!
    - abdominal trauma and surgery, ERCP!
    - peritoneal dialysis!
    - cardiopulmonary bypass!
    - drugs!
    - vasculitis!
    - infections : mumps, CMV, M avium complex!
    - Celiac disease!
    - pancreatic or ampullary neoplasm!
    - anatomic anomalies!
    - pancreas divisum -> dorsal and ventral pancreatic ducts fail to join!
    - anomalous union of the pancreaticobiliary duct!

    Drugs causing pancreatitis mnemonic!


    GLAD Organ Pancreas iS Traumatised n Destroyed Very Much!
    Glucocorticoids!
    L-asparaginase!
    Alcohol, antibiotic (tetracyclines,metronidazole), azathioprine!
    Diuretics (thiazide, enalapril)!
    Oral contraceptives, tamoxifen!
    Pentamidine!
    Sulfonamides!
    Tetracyclines!
    Didanosine!
    Valproate!
    Methyldopa!

    Ranson criteria mnemonic!


    at admission : WALLS!
    W!
    WBC! !
    !
    !
    A!
    Age!
    L!
    LDH!
    L!
    Liver enzyme (AST)
    S!
    Sugar!
    after 48 hours : FOr CHUB!
    F!
    Fluid requirement!
    O!
    pAO2!
    C!
    Calcium!
    H!
    Hematocrit!
    U!
    Urea!
    B!
    Base deficit!

    HAPS (Harmless acute pancreatitis score)!


    1. absence of rebound tenderness or guarding!
    2. normal hematocrit!
    3. normal serum creatinine!
    all features present = nonsevere course 98% accurate

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