GOOD LUCK on your finals! And study hard!

The exam will focus mostly on the latter half

of class, so study that first and in more detail!
P.S. If you have time, please complete evals! I will read mine, but they are anonymous!

Week 10 Worksheet
1. Why is Na+ unable to traverse the K+ Channel?
The conserved sequence and arrangement of the selectivity filter is fitted for K+.
The carbonyl backbones will act as a surrogate water binding to the K+ more
effectively than water itself. K+ typically has 8 water molecules whereas Na+
requires 6.

2.
3.

4.
5.

a. If the selectivity filter binds K+ so well, how is K+ able to flow through?

Electrostatic repulsion
The Light Harvesting Complex help trap light to help chlorophylls accept light.
LH2 has 9 pairs of identical unitseach containing an alpha and beta ring
that span the membrane.
a. It forms a hollow cylinder with alpha chains forming the inner wall and
beta chains forming the outer wall.
b. 3 chlorophylls/subunit, arranged to cover all possibilities of photon
acceptance.
i. 1 in between beta subunits and parallel to the plane of subunits
ii. 2 in between alpha subunits perpendicular to plane.
1. His residue sticks out stabilizing the Mg2+ ion in the
center
LH1 has 18 pairs of identical subunits
a. Larger than LH2, to fit the PRC (Photosynthetic Reaction Center)
b. Collects e- in LH2
Label the reaction center below

6. X-Ray Diffraction involves interactions of x-rays with e- to visualize molecules

in crystal form. NMR uses an external magnetic field to measure internal
magnetic properties via spin angular momentum. Both require energy
interaction with the molecule.