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  • Pathophysiology: The Patient Compensates

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    Connie Tayamen
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    The document describes the pathophysiology of colon cancer. It discusses risk factors like red meat consumption and lack of exercise. Multiple DNA mutations in epithelial cells can lead to the progression of adenomas to carcinomas, which involves angiogenesis, cell division, and invasion. Physical signs include a bulky colonic mass, bleeding, an irregular colon shape, and abdominal masses or narrowing. Later stages involve obstruction, weight loss, blood in stool, and abdominal pain. A CT scan revealed a transverse colon mass in one patient, who underwent a segmental jejunum resection and had adenocarcinoma.

    Original Description:

    pathophysio of colon adenocarcinoma

    Original Title

    pathophysio of colon adenocarcinoma

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    The document describes the pathophysiology of colon cancer. It discusses risk factors like red meat consumption and lack of exercise. Multiple DNA mutations in epithelial cells can lead to the progression of adenomas to carcinomas, which involves angiogenesis, cell division, and invasion. Physical signs include a bulky colonic mass, bleeding, an irregular colon shape, and abdominal masses or narrowing. Later stages involve obstruction, weight loss, blood in stool, and abdominal pain. A CT scan revealed a transverse colon mass in one patient, who underwent a segmental jejunum resection and had adenocarcinoma.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    29 views1 page

    Pathophysiology: The Patient Compensates

    Uploaded by

    Connie Tayamen
    The document describes the pathophysiology of colon cancer. It discusses risk factors like red meat consumption and lack of exercise. Multiple DNA mutations in epithelial cells can lead to the progression of adenomas to carcinomas, which involves angiogenesis, cell division, and invasion. Physical signs include a bulky colonic mass, bleeding, an irregular colon shape, and abdominal masses or narrowing. Later stages involve obstruction, weight loss, blood in stool, and abdominal pain. A CT scan revealed a transverse colon mass in one patient, who underwent a segmental jejunum resection and had adenocarcinoma.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    PATHOPHYSIOLOGY

    Bowel
    Obstruction
    Wound Infection
    Skin trauma
    Bleeding

    Gastrointest
    inal System

    Polyp
    (Adenoma)

    1. Red Meat Food


    2. No or minimal
    exercise
    3. Alcohol
    drinking and
    1. 63 years old
    2. Hereditary
    diseases (due to
    unknown family
    DNA mutations

    - Multiple DNA
    mutations lead
    to advancement
    of adenoma
    formed at the
    epithelial cells to
    carcinoma
    (becomes
    malignant,
    uncapsulated
    and invasive)
    - Angiogenesis
    occurs
    (formation and
    maturation of
    blood vessels)
    - More division
    of cancer cells

    - Bulky mass
    which spreads
    over the
    colonic
    mucosal
    surface
    - Surface areas
    that appear red
    because it is
    bleeding
    - Colons shape
    becomes
    irregular
    - Carcinomas of
    the cecum and
    ascending
    Abdominal
    Mass
    Narrowing of
    colonic walls

    THE PATIENT
    COMPENSATES

    The patient is still


    underweight
    Abdominal pain
    persists
    The secreted bile is

    Sudden weight
    loss
    Blood in stool
    Feeling of
    being full
    Abdominal pain
    Nausea and
    Partial Small Bowel
    Obstruction
    Secondary to
    Transverse Colon

    Presence of
    Adenocarcinom
    a in the
    jejunum
    Losing
    approx. 10
    Hgb level: 120
    g/L
    Whole
    abdominal CT
    scan revealed
    transverse
    colon mass

    Procedure:
    Segmental
    resection
    of
    jejunum with
    primary
    Biopsy
    revealed
    adenocarcino
    ma polyp
    with
    hyperplastic
    Status post
    ex-lap
    jejunostomy,
    peritoneal
    lavage and
    tube
    ABG result of
    uncompensat
    ed metabolic

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