ASKORBIPOL

Vitamin C 100 mg

Komposisi
Tiap tablet mengandung
Vitamin C 100 mg
Indikasi
Mengobati
dan
mencegah
skorbut, sariawan dan sebagai
suplemen.
Kontraindikasi
Hipersensitif terhadap sodium,
tartrat, asam askorbat.
Mekanisme Kerja
Skorbut
disebabkan
karena
defisiensi vitamin C. Asam askorbat
penting dalam sintesis jaringan
konektif, yang menjadi penyebab
terjadinya pembusukan jaringan
elastin sehingga terjadinya skorbut.
Farmakokinetika
Asam askorbat diserap dari
saluran pencernaan dan secara luas
didistribusikan
pada
jaringan.
Konsentrasi Plasma asam askorbat
meningkat seiring dengan dosis
tinggi dicapai, sekitar 90-150 mg
dalam sehari. Konsentrasi tertinggi
terdapat pada leukosit dan platelets
dibanding eritrosit dan plasma.
Asam askorbat dieliminasi melalui
urin.
Efek Samping
Dosis yang besar menyebabkan
diare dan masalah pencernaan
lainya, mual muntah, rasa panas
dalam perut, keram, kelelahan,
sakit kepala, dan insomnia.
Perhatian
- Ibu hamil dan menyusui
- Pasien hemolisis
- Pasien penyakit ginjal
Aturan Pakai
1-3 tablet dalam sehari
Simpan pada tempat sejuk
dan kering

Hypersensitive to sodium, tartrat,

ascorbic acid.
Working Mechanism
Ascorbic acid deficiency results in
scurvy. The importance of the role
of ascorbate in connective tissue
synthesis is evident in deterioration
of elastic tissue that occurs with
scurvy, the clinical ascorbic acid
deficiency disease.
Pharmacokinetics
Ascorbic acid is readily absorbed
from the gastrointestinal tract and
is widely distributed in the body
tissues. Plasma concentrations of
ascorbic acid rise as the dose
ingested is increased until a plateau
is reached with doses of about 90
to 150 mg daily. Body stores of
ascorbic acid in health are about
1.5 g although more may be stored
at intakes above 200 mg daily. The
concentration
is
higher
in
leucocytes and platelets than in
erythrocytes and plasma. Ascorbic
acid in excess of the bodys needs
is
also
rapidly
eliminated
unchanged in the urine.
Side Effects
In large dosage, adverse effect
diarrhea and GI tract disturbance,
nausea,
vomiting,
heartburn,
abdominal
cramps,
fatigue,
flushing, headache, and insomnia.
Attention

Ingredients
Each tablet contains
Vitamin C 100 mg
Indication
Ascorbic acid is used to prevent
and to treat scurvy, and as
supplement.

- Pregnancy and lactation

- Hemolysis patient
- Kidney disease patient
Dosage
1-3 tablet(s) each day.

Contra Indications
Store in a cool and dry place

PT. GASPOL
Makassar-Indonesia
No.Reg : DBL 160000100303 A1