What is the meaning of Amen as it is used in scripture?

The word Amen ("So be it; truly") is a declaration of affirmation found in the Hebrew
Bible and New Testament. It is often mentioned in Christian worship as a concluding
word for prayers, hymns, and an agreement of things to come or fulfilled.

Here are a few scriptures that give understanding of how the word is used.
The custom of closing prayers with amen originates in the Lord's Prayer at
Matthew 6:13
And lead us not into temptation, but deliver us from evil: For thine is the kingdom, and
the power, and the glory, for ever. Amen.

A double amen ("amen and amen") occurs in Psalm 89 (Psalm 41:13; 72:19; 89:52), to
confirm the words and invoke the fulfillment of them.

Amen establishes an agreement between 2 or more witnesses in the Word of God for
being on one accord with Christ; which now makes us accountable so that we may not
backslide against the agreement before God. See the examples below:

Revelation 3:13-16
13. that hath an ear, let him hear what the Spirit saith unto the churches.
14. unto the angel of the church of the Laodiceans write; These things saith the Amen, the
faithful and true witness, the beginning of the creation of God;
15. know thy works, that thou art neither cold nor hot: I would thou wert cold or hot.
16. then because thou art lukewarm, and neither cold nor hot, I will spue thee out of my
mouth.

1. John 5:21
Little children, keep yourselves from idols. Amen

Romans 1:25
Who changed the truth of God into a lie, and worshipped and served the creature more
than the Creator, who is blessed for ever. Amen.

Deuteronomy 27:15
Cursed be the man that maketh any graven or molten image, an abomination unto the
LORD, the work of the hands of the craftsman, and putteth it in a secret place. And all
the people shall answer and say, Amen.

Deuteronomy 27:26
Cursed be he that confirmeth not all the words of this law to do them. And all the people
shall say, Amen.