Pathophysiology

Non- Modifiable: Modifiable:

- 4th decade of life (women) Smoking
43 years old Type A personality (stressed
personality)
Type O blood

Exposure of Gastric Acid tissue to the acid

Decreased resistance of the mucosa

Erosion of the mucosa

Pain Ulceration Stimulation Bleeding Inflammation

(epigastric) of the
vagus
nerve
Local vasodilatation

Loss of
Appetite
Increased
Nausea & Anemia capillary
Vomiting permeability

Regurgitation Hematochesia
Weight Loss