Major Blocks of two or more nerves, or a plexus of nerves Brachial plexus block Peripheral nerve blocks The drug is usually selected based on the duration of anesthesia that is required
The duration of action of minor nerve block is
prolonged by the addition of epinephrine to the local anesthetic solution Infiltration of Local Anesthetics Agent is injected into the operative site without selectively blocking a specific nerve May be: Intradermal Subcutaneous Both Infiltration of Local Anesthetics The duration of action will vary
The addition of epinephrine will prolong the duration
of analgesia
Dilute anesthetic solutions are recommended for large
areas to avoid toxicity Infiltration of Local Anesthetics Infiltration of local anesthetic causes a painful, burning sensation
Injection into the dermis is the most painful and
provides the fastest onset of action
Addition of sodium bicarbonate decreases the pain
associated with infiltration Toxicity of Local Anesthetics To avoid toxicity, local anesthetics must be administered within a safe dose range and in the correct anatomic location
During local anesthesia, when toxic reaction occurs,
they are almost always the result of inadvertent intravascular injection or the administration of an excessively large dose Toxicity of Local Anesthetics Every efforts should be made to avoid intravascular injection
The syringe should always be aspirated before the local
anesthetic is injected regardless of the anatomic site of injection
An intravascular injection of an epinephrine
containing solution may produce a dangerously hypertensive response Toxicity of Local Anesthetics The addition of epinephrine to the anesthetic solution delays absorption and results in lower anesthetic blood levels, as well as a longer duration of the action
Epinephrine is especially useful when local anesthetic
is being injected into highly vascular areas such as the face Anatomy of the fifth cranial nerve ganglion (trigeminal) along with innervation and peripterygoid relationship Anatomy and needle-insertion plane of trigeminal ganglion block technique. See text for details and correlate with Picture 14
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