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  • Pa Tho Physiology

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    gagaah
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    The document discusses several factors that can lead to alcoholic hepatitis and cirrhosis of the liver. Sedentary lifestyle, hepatitis C, and alcohol abuse are listed as precipitating factors. A diagram then shows how alcohol is broken down in the body through various systems like the microsomal ethanol oxidizing system and alcohol dehydrogenase system, producing acetaldehyde and oxidative stress that can increase lipogenesis and decrease fatty acid oxidation, resulting in fatty liver and hepatocyte injury and potentially progressing to alcoholic hepatitis, fibrosis, and cirrhosis.

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    The document discusses several factors that can lead to alcoholic hepatitis and cirrhosis of the liver. Sedentary lifestyle, hepatitis C, and alcohol abuse are listed as precipitating factors. A diagram then shows how alcohol is broken down in the body through various systems like the microsomal ethanol oxidizing system and alcohol dehydrogenase system, producing acetaldehyde and oxidative stress that can increase lipogenesis and decrease fatty acid oxidation, resulting in fatty liver and hepatocyte injury and potentially progressing to alcoholic hepatitis, fibrosis, and cirrhosis.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    4 views1 page

    Pa Tho Physiology

    Uploaded by

    gagaah
    The document discusses several factors that can lead to alcoholic hepatitis and cirrhosis of the liver. Sedentary lifestyle, hepatitis C, and alcohol abuse are listed as precipitating factors. A diagram then shows how alcohol is broken down in the body through various systems like the microsomal ethanol oxidizing system and alcohol dehydrogenase system, producing acetaldehyde and oxidative stress that can increase lipogenesis and decrease fatty acid oxidation, resulting in fatty liver and hepatocyte injury and potentially progressing to alcoholic hepatitis, fibrosis, and cirrhosis.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 1

    Precipitating Factors:

    Hepatitis C
    Sedentary Lifestyle
    Alcohol Abuse

    Ethanol

    Small Intestine

    Liver

    Alcohol Microsomal Ethanol Catalase


    Dehydrogenase Oxidizing system
    System

    Acetyldehyde

    NADH production Lipid Peroxidase


    NADH Priduction

    Oxidative Stress
    Increase lipogenesis
    Decrease Fatty Acid
    oxidation

    Fatty liver Hepatocyte injury

    Alcoholic Hepatitis Liver Fibrosis

    Alcoholic Cirrhosis

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