gent Duration of Action Maximum Dosage Guidelines (Total

Cumulative Infiltrative Injection Dose per

Procedure*)

Esters    

Procaine (Novocain) Short (15-60 min) 7 mg/kg; not to exceed 350-600 mg

Chloroprocaine Short (15-30 min) Without epinephrine: 11 mg/kg; not to exceed

(Nesacaine) 800 mg total dose
With epinephrine: 14 mg/kg; not to exceed
1000 mg

Amides    

Lidocaine (Xylocaine) Medium (30-60 min) Without epinephrine: 4.5 mg/kg; not to exceed
300 mg

Lidocaine with Long (120-360 min) With epinephrine: 7 mg/kg

epinephrine

Mepivacaine (Polocaine, Medium (45-90 min) Long 7 mg/kg; not to exceed 400 mg
Carbocaine) (120-360 min with epinephrine)

Bupivacaine (Marcaine) Long (120-240 min) Without epinephrine: 2.5 mg/kg; not to exceed
175 mg total dose

Bupivacaine with Long (180-420 min) With epinephrine: Not to exceed 225 mg total
epinephrine dose

Etidocaine (Duranest) Long (120-180 min) Without epinephrine: 0.4 mg/kg; not to exceed
No longer available in 300 mg total dose
United States With epinephrine: 8 mg/kg

Prilocaine (Citanest) Medium (30-90 min) Body weight <70 kg: 8 mg/kg; not to exceed
500 mg
Body weight >70 kg: 600 mg

Ropivacaine (Naropin) Long (120-360 min) 5 mg; not to exceed 200 mg for minor nerve
block